Version 2.72

78202-99q34 chromosome region deletion [Presence] in Blood or Tissue by FISHActive

Term Description

This term was created for, but is not limited in use to, the Vysis 9q34 SpectrumAqua FISH Probe Kit, which is intended to detect deletion of the 9q34 chromosome region.
Source: Regenstrief LOINC

Part Descriptions

LP189751-3   9q34 chromosome region
A deletion of chromosome region 9q34 is associated with chronic myelogenous leukemia (CML). Most patients with CML have the characteristic t(9;22) (q34;q11.2) translocation that results in fusion of the BCR and ABL1 genes. A small subset of CML cases have the 9q34 deletion, which is associated with poor prognosis in CML patients under treatment with interferon therapy.[PMID:19222642] Fluorescence in situ Hybridization (FISH) is used to detect deletion of the 9q34 region around the argininosuccinate synthetase (ASS) gene. Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

9q34 chromosome region deletion

Additional Names

Short Name
9q34 Del Bld/T Ql FISH
Display Name
9q34 chromosome region del FISH Ql (Bld/Tiss)
Consumer Name Alpha
9q34 chromosome region deletion analysis, Blood or tissue specimen

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.54
Last Updated
Version 2.61
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
9q34 染色体区域 缺失:存在情况或阈值:时间点:全血/组织:序数型:FISH
nl-NLDutch (Netherlands)
9q34-chromosoomgebied deletie:aanwezigheid:moment:bloed of weefsel:ordinaal:FISH
fr-FRFrench (France)
Chromosome région 9q34 délétion:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:FISH
it-ITItalian (Italy)
Regione cromosomica 9q34 Delezione:PrThr:Pt:Sangue/Tess:Ord:FISH
es-MXSpanish (Mexico)
Deleción de la región del cromosoma 9q34:Presencia o umbral:Punto temporal:Sangre o tejido:Ordinal:Hibridación fluorescente in situ (FISH)
es-ESSpanish (Spain)
Región del cromosoma 9q34 Deleción:PrThr:Punto temporal:Sangre o tejido:Ord:Hibridación in situ fluoresente (FISH)
tr-TRTurkish (Turkey)
9q34 Kromozom bölgesi delesyon:MevcEşik:Zmlı:Kan/Dk:Srl:FISH

LOINC FHIR® API Example - CodeSystem Request Get Info