Version 2.77

Term Description

This term was created for, but is not limited in use to, the Vysis 9q34 SpectrumAqua FISH Probe Kit, which is intended to detect deletion of the 9q34 chromosome region.
Source: Regenstrief LOINC

Part Descriptions

LP189751-3   9q34 chromosome region
A deletion of chromosome region 9q34 is associated with chronic myelogenous leukemia (CML). Most patients with CML have the characteristic t(9;22) (q34;q11.2) translocation that results in fusion of the BCR and ABL1 genes. A small subset of CML cases have the 9q34 deletion, which is associated with poor prognosis in CML patients under treatment with interferon therapy. PMID: 19222642 Fluorescence in situ Hybridization (FISH) is used to detect deletion of the 9q34 region around the argininosuccinate synthetase (ASS) gene. Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
9q34 chromosome region deletion
Property
PrThr
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
FISH

Additional Names

Short Name
9q34 Del Bld/T Ql FISH
Display Name
9q34 chromosome region del FISH Ql (Bld/Tiss)
Consumer Name Alpha Get Info
9q34 chromosome region deletion analysis, Blood or tissue specimen

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MOLPATH.DEL
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.61
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Región del cromosoma 9q34 Deleción:PrThr:Punto temporal:Sangre o tejido:Ord:Hibridación in situ fluoresente (FISH)
es-MX Spanish (Mexico) Deleción de la región del cromosoma 9q34:Presencia o umbral:Punto temporal:Sangre o tejido:Ordinal:Hibridación fluorescente in situ (FISH)
fr-FR French (France) Chromosome région 9q34 délétion:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:FISH
it-IT Italian (Italy) Regione cromosomica 9q34 Delezione:PrThr:Pt:Sangue/Tess:Ord:FISH
Synonyms: Delezione genetica Ibridazione in situ fluorescente (FISH) Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) 9q34-chromosoomgebied deletie:aanwezigheid:moment:bloed of weefsel:ordinaal:FISH
Synonyms: 9q34-chromosoom gebied
pl-PL Polish (Poland) Region chromosomowy 9q34 delecja:granica wykrywalności:punkt w czasie:krew lub tkanka:półilościowy:fluorescencyjna hybrydyzacja in situ (FISH)
Synonyms: Delecja prążka 34 długiego ramienia chromosomu 9
tr-TR Turkish (Turkey) 9q34 Kromozom bölgesi delesyon:MevcEşik:Zmlı:Kan/Dk:Srl:FISH
Synonyms: Mevcut
zh-CN Chinese (China) 9q34 染色体区域 缺失:存在情况或阈值:时间点:全血/组织:序数型:FISH
Synonyms: 9q34 染色体区域(染色体部位、染色体区、染色体区带、染色体部) Fluorescent in situ hybridization;荧光原位杂交 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因缺失;分子病理学.缺失;分子病理学试验.基因缺失;分子病理学试验.缺失;分子病理学试验类.缺失;基因缺失;缺失 分子病理学;分子病理学试验 区;地区;局部 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体二体型+染色体三体型 染色体缺失;染色体区带缺失;基因缺失;缺损;基因缺损;基因删除;删除;基因丢失 染色体部位;染色体区;染色体区带;染色体部;染色体区域(染色体部位、染色体区、染色体区带、染色体部) 血;血液

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