Version 2.78

26589-2 Beta alanine [Moles/volume] in Cerebral spinal fluid

Part Descriptions

LP15431-7   Beta alanine
In biochemistry, beta-alanine is the only naturally occurring beta amino acid, which are amino acids in which the amino group is at the -position from the carboxylate group (i.e., two atoms away). The IUPAC name for beta-alanine would be 3-aminopropionic acid. Unlike its normal counterpart, L-alanine, beta-alanine has no chiral center. beta-alanine is not used in the biosynthesis of any major proteins or enzymes. It is formed in vivo by the degradation of dihydrouracil and carnosine. It is a component of the naturally occurring peptides carnosine and anserine and also of pantothenic acid (Vitamin B-5) which itself is a component of coenzyme A. Under normal conditions, beta-alanine is metabolized into acetic acid. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Beta alanine (Wikipedia)

LP15431-7   Beta alanine
Beta-Alanine is an amino acid metabolite converted from Anserine. Formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been shown, the compound may be a false transmitter replacing Gamma-aminobutyric acid(GABA). Increased with Hyper Beta-Alanemia, a rare genetic disorder. Information from Online Medical Dictionary.org 2006 12 22. Source: Regenstrief Institute

Fully-Specified Name

Component
Beta alanine
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
B-Alanine CSF-sCnc
Display Name
Beta alanine (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
Beta alanine, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
8764

Member of these Panels

LOINC Long Common Name
35507-3 Amino acids panel [Moles/volume] - Cerebral spinal fluid
79603-7 Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG44298-4 Beta alanine|Pt|CSF

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Beta-Alanin /L
de-DE German (Germany) Beta-Alanin:Stoffmengenkonzentration:Zeitpunkt:Liquor:Quantitativ:
Synonyms: Zerebrospinalflüssigkeit
es-AR Spanish (Argentina) beta alanina:concentración de sustancia:punto en el tiempo:líquido cefalorraquídeo:cuantitativo:
es-MX Spanish (Mexico) Beta alanina:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
es-ES Spanish (Spain) Beta alanina:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Beetaalaniin:SCnc:Pt:CSF:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Liikvor
fr-BE French (Belgium) Béta-alanine:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
fr-FR French (France) Bêta alanine:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-CA French (Canada) Bêta-alanine:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
it-IT Italian (Italy) Beta alanina:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 베타 알라닌:물질농도:검사시점:뇌척수액:정량:
nl-NL Dutch (Netherlands) bèta-alanine:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pt-BR Portuguese (Brazil) Beta alanina:SCnc:Pt:LCR:Qn:
Synonyms: ; B-Alanine; Bala; B-Ala; Ala; L-alanine; Alpha alanine; Substance concentration; Level; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; B; Chemistry
ru-RU Russian (Russian Federation) Бета аланин:МолКонц:ТчкВрм:ЦСЖ:Колич:
Synonyms: Бета-аланин Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Beta alanin:SubKons:Zmlı:BOS:Kant:
uk-UA Ukrainian (Ukraine) Бета аланін:Молярна Концентрація:МоментЧасу:Спинномозкова рідина:Кількісно:
Synonyms: Ala; Alpha alanine; B; Bala; B-Ala; B-Alanine; Cerebral spinal fluid; Cerebrospinal Fl; Chemistry; L-alanine; Level; Point in time; QNT; Quan; Quant; Quantitative; Random; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; Substance concentration
zh-CN Chinese (China) Beta 丙氨酸:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: Ala;Alpha 丙氨酸;Alpha-丙氨酸;L-Ala;L-丙氨酸;α丙氨酸;α-丙氨酸;丙胺酸 B B-Ala;Beta-丙氨酸;β丙氨酸;β-丙氨酸 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 β 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 贝塔

Example Units

Unit Source
umol/L Example UCUM Units
umol/L eCHN

26590-0 Beta aminoisobutyrate [Moles/volume] in Cerebral spinal fluid

Part Descriptions

LP15432-5   Beta aminoisobutyrate
3-Aminoisobutyric acid is a product formed by the catabolism of thymine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP15432-5   Beta aminoisobutyrate
Beta aminoisobutyric acid (BAIB) is a nonprotein amino acid that is an end product of pyrimidine metabolism. The R and S enantiomers (previously named D-(minus)-BAIB and L-plus-BAIB) are produced from thymine and L-valine, respectively. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with dihydropyrimidine dehydrogenase deficiency, thymine catabolism is decreased, which results in moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated despite decreased breakdown of thymine, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Deficiency of D-beta-aminoisobutyrate:pyruvate aminotransferase (EC 2.6.1.40) , an enzyme that is involved in the catabolism R-BAIB, also results in elevated urine BAIB and is associated with hyperuricemia. [OMIM: 210100] Source: Regenstrief LOINC, PMID: 14705962

Fully-Specified Name

Component
Beta aminoisobutyrate
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
B-AIB CSF-sCnc
Display Name
Beta aminoisobutyrate (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
Beta aminoisobutyrate, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
8792

Member of these Panels

LOINC Long Common Name
35507-3 Amino acids panel [Moles/volume] - Cerebral spinal fluid
79603-7 Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG48155-2 Beta aminoisobutyrate|Pt|CSF

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Beta-Aminoisobuttersäure /L
de-DE German (Germany) Beta-Aminoisobutyrat:Stoffmengenkonzentration:Zeitpunkt:Liquor:Quantitativ:
Synonyms: Zerebrospinalflüssigkeit
es-MX Spanish (Mexico) Beta aminoisobutirato:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
es-ES Spanish (Spain) Beta aminoisobutirato:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-AR Spanish (Argentina) beta aminoisobutirato:concentración de sustancia:punto en el tiempo:líquido cefalorraquídeo:cuantitativo:
et-EE Estonian (Estonia) Beetaaminoisobutüraat:SCnc:Pt:CSF:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Liikvor
fr-BE French (Belgium) Béta-aminoisobutyrate:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
fr-FR French (France) Bêta aminoisobutyrate:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-CA French (Canada) Bêta-aminoisobutyrate:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
it-IT Italian (Italy) Beta aminoisobutirrato:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 베타 아미노이소뷰티레이트:물질농도:검사시점:뇌척수액:정량:
nl-NL Dutch (Netherlands) bèta-amino-isobutyraat:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pt-BR Portuguese (Brazil) Beta aminoisobutirato:SCnc:Pt:LCR:Qn:
Synonyms: ; B-AIB; 3-aminoisobutyrate; 3-aminoisobutyric acid; Substance concentration; Level; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; B; Chemistry
ru-RU Russian (Russian Federation) Бета аминоизобутират:МолКонц:ТчкВрм:ЦСЖ:Колич:
Synonyms: Бета-аминоизобутират Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Beta aminoizobütirat:SubKons:Zmlı:BOS:Kant:
uk-UA Ukrainian (Ukraine) Бета аміноізобутират:Молярна Концентрація:МоментЧасу:Спинномозкова рідина:Кількісно:
Synonyms: 3-aminoisobutyrate; 3-aminoisobutyric acid; B; B-AIB; Cerebral spinal fluid; Cerebrospinal Fl; Chemistry; Level; Point in time; QNT; Quan; Quant; Quantitative; Random; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; Substance concentration
zh-CN Chinese (China) Beta 氨基异丁酸:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: 3-氨基异丁酸;B-AIB;Beta-氨基异丁酸;β氨基异丁酸;β-氨基异丁酸 B CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 β 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 贝塔

Example Units

Unit Source
umol/L Example UCUM Units

72420-3 Gamma aminobutyrate.free [Moles/volume] in Cerebral spinal fluid

Part Descriptions

LP157335-3   Gamma aminobutyrate.free
Free GABA levels may be elevated in the CSF of patients suffering from neurological diseases with inflammation and tissular necrosis such as cerebral cysticercosis. Source: Regenstrief LOINC

Fully-Specified Name

Component
Gamma aminobutyrate.free
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
GABA. free CSF-sCnc
Display Name
Gamma aminobutyrate.free (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
Free gamma aminobutyrate, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.44
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79603-7 Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate panel - Cerebral spinal fluid
74439-1 GABA free and total panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Gamma aminobutirato gratuito:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
es-ES Spanish (Spain) Gamma aminobutirato.libre:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Gamma aminobutyrate libre:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
it-IT Italian (Italy) Gamma amminobutirrato.libero:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) gamma-aminobutyraat.vrij:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pt-BR Portuguese (Brazil) Gama aminobutirato.livre::Pt:LCR:Qn:
ru-RU Russian (Russian Federation) Гамма аминобутират.свободный:МолКонц:ТчкВрм:ЦСЖ:Колич:
Synonyms: ГАМК.свободный Гамма-аминобутират Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Gamma aminobutirat.serbest:SubKons:Zmlı:BOS:Kant:
zh-CN Chinese (China) Gamma 氨基丁酸.游离型:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: 4-氨基丁酸;GABA;Gamma 氨基丁酸（Gamma aminobutyric acid，GABA）;Gamma-氨基丁酸;G-氨基丁酸;γ氨基丁酸;γ-氨基丁酸;哌啶酸 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 氨基-n-丁酸 氨基丁酸盐 氨基丁酸酯 游离 游离型 4-氨基丁酸;GABA;Gamma 氨基丁酸（Gamma aminobutyric acid，GABA）;游离型 Gamma-氨基丁酸;游离型 G-氨基丁酸;游离型γ氨基丁酸;游离型γ-氨基丁酸;哌啶酸 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
umol/L Example UCUM Units

79642-5 Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate pattern [Interpretation] in Cerebral spinal fluid Narrative

Part Descriptions

LP201667-5   Beta alanine & Beta aminoisobutyrate & Gamma aminobutyrate pattern
Changes in the CSF, plasma and urine levels of beta alanine, beta aminoisobutyrate (BAIB) and gamma aminobutyrate (GABA) may help identify certain metabolic disorders. Beta alanine is a structural analogue of GABA and may also function as a neurotransmitter since it is both a glycine and GABAA receptor agonist. Dihydropyrimidine dehydrogenase (DPD) is the first enzyme in the pyrimidine degradation pathway, in which uracil and thymine are catabolized to beta alanine and R-BAIB, respectively. The S enantiomer of BAIB (S-BAIB) is derived from valine catabolism. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with a DPD deficiency, uracil and thymine catabolism is decreased. This results in mildly decreased plasma and urine concentrations and normal CSF concentration of beta alanine, and moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Source: Regenstrief LOINC, PMID: 14705962

Fully-Specified Name

Component
Beta alanine & Beta aminoisobutyrate & Gamma aminobutyrate pattern
Property
Imp
Time
Pt
System
CSF
Scale
Nar
Method

Additional Names

Short Name
B-Alanine + B-AIB + GABA patt CSF-Imp
Display Name
Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate pattern Nar (CSF) [Interp]
Consumer Name Alpha Get Info
Interpretation of Beta alanine and beta aminoisobutyrate and Gamma aminobutyrate pattern test result, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.58
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
79603-7 Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Patrón de beta alanina y beta aminoisobutirato y gamma aminobutirato:Impresión / interpretación del estudio:Punto temporal:Fluído espinal cerebral:Narrativo:
es-ES Spanish (Spain) Patrón de Beta alanina y Beta aminoisobutirato y Gamma aminobutirato:Impresión/interpretación del estudio:Punto temporal:Líquido Cefalorraquideo:Narrativo:
fr-FR French (France) Bêta alanine et bêta aminoisobutyrate et gamma aminoisobutyrate Profil:Interprétation:Ponctuel:Liquide céphalorachidien:Résultat textuel:
it-IT Italian (Italy) Beta alanina & Beta aminoisobutirrato & Gamma aminoisobutirrato, profilo:Imp:Pt:LCS:Nar:
Synonyms: Chimica Impressione/interpretazione di studio Liquido cerebrospinale Profilo di Beta alanina & Beta aminoisobutirrato & Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) bèta-alanine & bèta-aminoisobutyraat & gamma-aminobutyraat patroon:interpretatie:moment:liquor cerebrospinalis:tekstueel:
Synonyms: beta alanine & Beta aminoisobutyraat & Gamma aminobutyraat patroon
tr-TR Turkish (Turkey) Beta alanin ve Beta aminoizobütirat ve Gamma aminobutirat örüntüsü:İzlnm:Zmlı:BOS:Öykü:
Synonyms: Beta alanin ve Beta aminoizobütirat ve Gamma aminobutirat paterni
zh-CN Chinese (China) Beta 丙氨酸与 Beta 氨基异丁酸与 Gamma 氨基丁酸模式:印象:时间点:脑脊液:叙述型:
Synonyms: 3-氨基异丁酸;B-AIB;Beta-氨基异丁酸;β氨基异丁酸;β-氨基异丁酸 4-氨基丁酸;GABA;Gamma 氨基丁酸（Gamma aminobutyric acid，GABA）;Gamma-氨基丁酸;G-氨基丁酸;γ氨基丁酸;γ-氨基丁酸;哌啶酸 Ala;Alpha 丙氨酸;Alpha-丙氨酸;L-Ala;L-丙氨酸;α丙氨酸;α-丙氨酸;丙胺酸 B B-Ala;Beta-丙氨酸;β丙氨酸;β-丙氨酸 Beta 丙氨酸（β丙氨酸、β-丙氨酸）与 Beta 氨基异丁酸（β氨基异丁酸、β-氨基异丁酸）与 Gamma 氨基丁酸（γ氨基丁酸、γ-氨基丁酸）模式（模式特征、特征模式、图谱、式样、组份、组分、成员） CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 β 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 时刻;随机;随意;瞬间 氨基-n-丁酸 氨基丁酸盐 氨基丁酸酯 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 贝塔