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Part Descriptions

LP212220-0   Microsatellite markers exhibiting instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

LP212221-8   Microsatellite instability markers assessed
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Microsatellite markers exhibiting instability/Microsatellite instability markers assessed:NFr:Pt:Cancer specimen:Qn:
Long Common Name
Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen
Short Name
MSI mark found/MSI mark stud NFr Ca spec
Display Name
Microsatellite markers exhibiting instability/Microsatellite instability markers assessed (Cancer specimen)
Consumer Name Alpha Get Info
Microsatellite markers exhibiting instability/Microsatellite Instability Markers Assessed, Cancer specimen

Part Model Get Info

  • Component
    Microsatellite markers exhibiting instability/Microsatellite instability markers assessed
    LP286542-8
    • Analyte
      Microsatellite markers exhibiting instability/Microsatellite instability markers assessed
      LP286542-8
      • Component Numerator
        Microsatellite markers exhibiting instability
        LP212220-0
        • Component Numerator Core
          Microsatellite markers exhibiting instability
          LP212220-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Microsatellite instability markers assessed
        LP212221-8
        • Component Denominator Core
          Microsatellite instability markers assessed
          LP212221-8
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Cancer specimen
    LP247830-5
    • System Core
      Cancer specimen
      LP247830-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.61 (MAJ)
Change Reason
Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
85905-8Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Markery mikrosatelitů signalizující nestabilitu/hodnocené markery nestability mikrosatelitů:Početní podíl:Časový bod:Vzorek karcinomu:Kvantitativní:
el-GRGreek (Greece)Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια/Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας:NFr:Pt:Δείγμα καρκίνου:Qn:
Synonyms: NFr PATH Pt Qn Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορική αστάθεια Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια
es-ESSpanish (Spain)Marcadores de inestabilidad de microsatelites/Marcadores de inestabilidad de microsatélites evaluados:Fracción numérica:Punto temporal:Muestra de cancer:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Marcadores de microsatélites que presentan inestabilidad / Marcadores de inestabilidad de microsatélites evaluados:Fracción numérica:Punto temporal:Espécimen de cáncer:Cuantitativo:
it-ITItalian (Italy)Marcatori di microsatelliti che dimostrano instabilità/Marcatori di instabilità dei microsatelliti valutati:NFr:Pt:Campione tumore:Qn:
Synonyms: Campione di tumore Frazione numerica Instabilità dei microsatelliti Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CNChinese (China)表现不稳定性的微卫星标记/所评估的微卫星不稳定性标记:计数型分数:时间点:癌标本:定量型:
Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 所评估的（已评估的、所评价的、已评价的）微卫星不稳定性（MSI）标记（标记物、标志、标志物） 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 样品 样本 癌 癌（癌症、癌变）标本（样本、样品、试样） 表现（展现、体现、显现、显示、存在）不稳定性的微卫星标记 试样

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81708-0