Version 2.78

Status Information

Status
DEPRECATED
Reason
Duplicate
Comment
Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.
Map-To Long Common Name Mapping Guidance
63533-4 Centromere protein B Ab [Presence] in Cerebral spinal fluid by Immunoassay

Part Description

LP71684-2   Centromere protein B Ab
Major centromere autoantigen B, also known as centromere protein B or CENP-B, is encoded by the CENPB gene located on chromosome 20p13. CENP-B interacts with chromosomal centromeric heterochromatin and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. [UniProt: P07199] CENP-B plays a direct role in stablizing CENP-C, which is a kinetochore assembly nucleator, and recruiting CENP-A, which marks and maintains centromere position. Chromosomes that have centromeres without bound CENP-B, including the human Y chromosome, are more likely to missegregate at much higher rates than chromosomes with CENP-B containing centromeres. PMID: 25942623 Autoantibodies to both CENP-A and CENP-B are markers for scleroderma and other rheumatic diseases. PMID: 17210244 Source: Regenstrief LOINC, UniProt: P07199

Fully-Specified Name

Component
Centromere protein B Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IB

Additional Names

Short Name
Deprecated Centromere B Ab CSF Ql IB
Display Name
Centromere protein B Ab IB Ql (CSF)
Consumer Name Alpha Get Info
Centromere Protein B antibody, Spinal fluid

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.58
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG29561-4 Centromere protein B Ab|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Proteína B del centrómero Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunoblot (IB)
es-MX Spanish (Mexico) Centrómero de proteína B Ab:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunotransferencia
et-EE Estonian (Estonia) Tsentromeer B vastased antikehad:PrThr:Pt:CSF:Ord:IB
Synonyms: Järgarvuline Juhuslik Liikvor
fr-CA French (Canada) Centromère protéine B, Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoblot
fr-BE French (Belgium) Centromère. Protéine B Ac:PrThr:Temps ponctuel:LCR:Ordinal:Immunoblot
Synonyms: Anticorps
it-IT Italian (Italy) Centromero, proteina B Ab:PrThr:Pt:LCS:Ord:IB
Synonyms: anticorpo Immunoblot (IB) Liquido cerebrospinale Presenza o Soglia Proteina B del centromero Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) centromeereiwit B As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoblotting
Synonyms: antistof; antilichaam IB
ru-RU Russian (Russian Federation) Центромерный протеин B Ат:PrThr:ТчкВрм:ЦСЖ:Пор:ИБ
Synonyms: Антитело Белок Иммуноблот (ИБ) Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Sentromer protein B Ab:MevcEşik:Zmlı:BOS:Srl:IB
Synonyms: Ak Mevcut
zh-CN Chinese (China) 着丝点蛋白 B 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫印迹法
Synonyms: Ab;自身抗体 B 型 B型抗体 CRST 综合征;着丝粒;动粒 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 着丝粒蛋白 B;动粒蛋白 B 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81715-5