82193-4

Parechovirus A RNA [Presence] in Cerebrospinal Fluid by NAA with non-probe detection

Active

Term Description

This assay detects the presence of nucleic acid sequences from the Human parechovirus RNA in cerebrospinal fluid (CSF) using PCR and non-probe based detection methods, such as melt curve analysis. This term was created for, but is not limited in use to, BioFire's FilmArray Meningitis/Encephalitis Panel, which is intended for the detection and identification of nucleic acids from multiple bacteria, viruses, and yeast directly from CSF obtained via lumbar puncture from individuals with signs and/or symptoms of meningitis and/or encephalitis.

Part Description

LP262453-6 Parechovirus A
The Parechovirus belongs to the family Picornaviridae and is a small, nonenveloped RNA virus with icosahedral capsids. There are two species of Parechovirus including Parechovirus A (HPeV), previously named Human parechovirus, and Parechovirus B, previously named Ljungan virus. HPeV is made up of nineteen types designated as HPeV-1 to HPeV-19. Human infection by HPeV occurs worldwide and is often asymptomatic. Transmission of HPeV is by the fecal-oral route, respiratory secretions and fomites. When symptoms occur, they usually consist of mild gastroenteritis and respiratory symptoms. More serious disease has been attributed to HPeV-3, which can cause neonatal sepsis and aseptic meningitis in children. In 9 out of 10 neonates infected with HPeV-3, there is white matter damage which can lead to cerebral palsy, epilepsy and learning disabilities. There is no FDA approved anti-viral treatment for HPeV available, though there are some therapies in development that target viral capsid proteins, proteases and polymerase. http://www.picornaviridae.com/parechovirus/parechovirus.htm https://wwwnc.cdc.gov/eid/article/20/1/pdfs/13-0569.pdf Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Parechovirus A RNA:PrThr:Pt:CSF:Ord:Non-probe.amp.tar
Long Common Name: Parechovirus A RNA [Presence] in Cerebrospinal Fluid by NAA with non-probe detection
Short Name: Parechovirus A RNA CSF Ql NAA+n-prb
Display Name: Parechovirus A RNA NAA+non-probe Ql (CSF)
Consumer Name Alpha Get Info: Parechovirus A, Spinal fluid

Part Model Get Info

Component
Parechovirus A RNA
LP101464-8
- Analyte
  Parechovirus A RNA
  LP101464-8
  - Component Numerator
    Parechovirus A RNA
    LP101464-8
    - Component Numerator Core
      Parechovirus A
      LP262453-6
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Non-probe.amp.tar
LP208998-7

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.83 (MIN)
Change Reason: Updated Component from 'Human parechovirus' to 'Parechovirus A' according to the currently accepted nomenclature.http://www.picornaviridae.com/parechovirus/parechovirus.htm
Order vs. Observation: Both
Common Test Rank Get Info: 2615

Member of these Panels

LOINC	Long Common Name
82180-1	Meningitis+Encephalitis pathogens panel - Cerebrospinal Fluid by NAA with non-probe detection

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Parechovirus A RNA:Přítomnost nebo práh:Časový bod:Mozkomíšní mok:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
el-GR	Greek (Greece)	Παρεκοϊός Α RNA:PrThr:Pt:ΕΝΥ:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου Synonyms: A MICRO Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου ΕΝΥ Παρεκοϊός Παρεκοϊός Α Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Parechovirus A RNA:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda
es-MX	Spanish (Mexico)	Parechovirus A ARN:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-CA	French (Canada)	Paréchovirus A ARN:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Non-sonde.amplification de cible
fr-FR	French (France)	Paréchovirus A ARN:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Non-PCR amplification de cible
it-IT	Italian (Italy)	Parechovirus A RNA:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar Synonyms: Amplificazione target non basata su sonda Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
pl-PL	Polish (Poland)	Parechowirus A RNA:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:uporządkowany:bez sondy.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Ludzki parechowirus Ludzki parechowirus A RNA ludzkiego parechowirusa A
zh-CN	Chinese (China)	副肠孤病毒 A RNA:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向 Synonyms: A 型 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向副肠孤病毒（双埃柯病毒、双埃可病毒） A 双埃柯病毒属;副肠孤病毒属;双埃柯病毒;双埃可病毒;Parechovirus;PeV;副腸孤病毒屬存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液脱氧核糖核酸探针

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.