82212-2

Rotavirus A RNA [Presence] in Stool by NAA with non-probe detection

Active

Term Description

Qualitative detection of nucleic acid sequences in the Rotavirus A RNA in stool specimens by PCR and non-probe detection methods, such as melt curve analysis. This term was created for, but not limited in use to, the submitter's test kit, FilmArray Gastrointestinal Panel (GI) v2.1.

Part Description

LP204843-9 Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. PMID: 2556635 http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub PMID: 27462899 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Rotavirus A RNA:PrThr:Pt:Stool:Ord:Non-probe.amp.tar
Long Common Name: Rotavirus A RNA [Presence] in Stool by NAA with non-probe detection
Short Name: RVA RNA Stl Ql NAA+n-prb
Display Name: Rotavirus A RNA NAA+non-probe Ql (Stl)
Consumer Name Alpha Get Info: Rotavirus A, Stool

Part Model Get Info

Component
Rotavirus A RNA
LP220378-6
- Analyte
  Rotavirus A RNA
  LP220378-6
  - Component Numerator
    Rotavirus A RNA
    LP220378-6
    - Component Numerator Core
      Rotavirus A
      LP204843-9
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Stool
LP7604-4
- System Core
  Stool
  LP7604-4
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Non-probe.amp.tar
LP208998-7

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.82 (MIN)
Change Reason: Abbreviated "Rotavirus A" to "RVA" in the Shortname for consistency across terms.
Order vs. Observation: Both
Common Test Rank Get Info: 1264

Member of these Panels

LOINC	Long Common Name
114488-0	Gastrointestinal pathogens 22-plexA DNA and RNA panel - Stool by NAA with non-probe detection
82195-9	Gastrointestinal pathogens DNA and RNA panel - Stool by NAA with non-probe detection

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Rotavirus A RNA:Přítomnost nebo práh:Časový bod:Stolice:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
de-DE	German (Germany)	Rotavirus A RNA:Nachweis oder Schwellenwert:Zeitpunkt:Stuhl:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
el-GR	Greek (Greece)	Ροταϊός Α RNA:PrThr:Pt:Κόπρανα:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου Synonyms: A MICRO Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Κόπρανα Ροταϊός Ροταϊός Α Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Rotavirus A RNA:PrThr:Punto temporal:Heces:Ord:Amplificación del objetivo no basado en sonda
es-MX	Spanish (Mexico)	ARN del rotavirus A:Presencia o umbral:Punto temporal:Heces:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-FR	French (France)	Rotavirus A ARN:Présence/Seuil:Ponctuel:Selle:Qualitatif:Non-PCR amplification de cible
it-IT	Italian (Italy)	Rotavirus A RNA:PrThr:Pt:Feci:Ord:Non-sonda.amp.tar Synonyms: Amplificazione target non basata su sonda Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
pl-PL	Polish (Poland)	Rotawirus grupy A RNA:granica wykrywalności:punkt w czasie:kał:uporządkowany:bez sondy.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA Rotawirusa A
zh-CN	Chinese (China)	轮状病毒 A 组 RNA:存在情况或阈值:时间点:大便:序数型:非探针法.基因扩增.靶向 Synonyms: A 型 ROTAV;RV 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型便;大肠运动;排便;粪便;肠运动借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针轮状病毒（ROTAV、RV） A 组;A 组轮状病毒

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.