Term Description

Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16 in cervical specimens from women with positive HPV screening assay results. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay.To report results for HPV 18/45 use Human papilloma virus 18+45 E6+E7 mRNA [Presence] in Cervix by Probe and signal amplification method LOINC 75694-0.

Part Description

LP221166-4   Human papilloma virus 16 E6+E7 mRNA
Human papilloma virus (HPV) is a double-stranded DNA virus that includes 120 types that infect cutaneous and mucosal epithelial cells. The HPV that infect the cervix are categorized as low or high risk depending upon their carcinogenicity. High risk HPV types can lead to low-grade cervical cell abnormalities, pre-cancerous cellular abnormalities and anogenital cancer. Type 16 is a high risk HPV and is implicated in roughly 50% of cervical cancers around the world. E6/E7 genes in cervical tumors interfere with the control of cell proliferation and cell division and can be used for targeted anti-cancer therapy. PMID: 9448307 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Human papilloma virus 16 E6+E7 mRNA:PrThr:Pt:Cvx:Ord:Probe.amp.tar
Long Common Name
Human papilloma virus 16 E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
Short Name
HPV 16 E6+E7 mRNA Cvx Ql NAA+probe
Display Name
HPV 16 E6+E7 mRNA NAA+probe Ql (Cvx)
Consumer Name Alpha Get Info
HPV 16 E6+E7 MRNA, Cervix

Part Model Get Info

  • Component
    Human papilloma virus 16 E6+E7 mRNA
    LP221166-4
    • Analyte
      Human papilloma virus 16 E6+E7 mRNA
      LP221166-4
      • Component Numerator
        Human papilloma virus 16 E6+E7 mRNA
        LP221166-4
        • Component Numerator Core
          Human papilloma virus 16 E6+E7 mRNA
          LP221166-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Cvx
    LP7162-3
    • System Core
      Cvx
      LP7162-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Probe.amp.tar
    LP6464-4

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
4491

Member of these Panels

LOINCLong Common Name
90766-7HEDIS 2019 Value Sets
94137-7HEDIS 2020 Value Sets
96068-2HEDIS MY 2020 Value Sets
82457-3Human papilloma virus 16 and 18+45 E6+E7 mRNA panel - Cervix by NAA with probe detection

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Lidský papillomavirus 16 E6+E7 mRNA:Přítomnost nebo práh:Časový bod:Děložní hrdlo:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
el-GRGreek (Greece)Ιός ανθρώπινων θηλωμάτων 16 E6+E7 mRNA:PrThr:Pt:Cvx:Ord:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: Cvx MICRO Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός ανθρώπινων θηλωμάτων Ιός ανθρώπινων θηλωμάτων 16 Ιός ανθρώπινων θηλωμάτων 16 E6+E7 mRNA
es-ESSpanish (Spain)mRNA del virus 16E6+E7 del papiloma humano:PrThr:Punto temporal:Cuello uterino:Ord:Sonda con amplificación dirigida
es-MXSpanish (Mexico)ARNm del virus del papiloma humano 16 E6 + E7:Presencia o umbral:Punto temporal:Cuello uterino:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FRFrench (France)Papillomavirus humain 16 ARNm E6+E7:Présence/Seuil:Ponctuel:Col de l'utérus:Qualitatif:PCR amplification de cible
it-ITItalian (Italy)Papilloma virus umano 16 E6+E7 mRNA:PrThr:Pt:Cvx:Ord:Sonda.amp.tar
Synonyms: Cervice uterina Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NLDutch (Netherlands)Humaan papilloma virus 16 E6+E7 mRNA:aanwezigheid:moment:cervix:ordinaal:probe-detectie
Synonyms: baarmoederhals probe.amp.tar
pl-PLPolish (Poland)Wirus brodawczaka ludzkiego 16 E6+E7 mRNA:granica wykrywalności:punkt w czasie:szyjka macicy:uporządkowany:sonda.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy HPV HPV 16 HPV 16 E6+E7 mRNA
zh-CNChinese (China)人乳头瘤病毒 16 E6+E7 mRNA:存在情况或阈值:时间点:子宫颈:序数型:探针法.基因扩增.靶向
Synonyms: HPV 16 E6+E7 mRNA;HPV 高危型 mRNA;人乳头状瘤病毒 高危型 mRNA HPV 16;HPV 16 型;HPV16;人类乳头瘤病毒 16 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV;人乳头瘤病毒(Human papilloma virus,HPV);人类乳头瘤病毒;生殖器疣 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 宫颈;生殖道 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82456-5