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Part Description

LP19732-4   KRAS gene
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845] Source: National Center for Biotechnology Information (NCBI) Gene

LOINC Names Get Info

Fully-Specified Name
KRAS gene mutations:Prid:Pt:Colorectal cancer specimen:Nom:Targeted gene mutation analysis
Long Common Name
KRAS gene mutations found [Identifier] in Colorectal cancer specimen by Targeted gene mutation analysis Nominal
Short Name
KRAS gene Mut CRC spec Mut Anl
Display Name
KRAS gene mutations found Targeted gene mutation analysis Nom (Colorectal cancer specimen)
Consumer Name Alpha Get Info
KRAS gene mutations found, Colorectal cancer specimen

Part Model Get Info

  • Component
    KRAS gene mutations
    LP451925-4
    • Analyte
      KRAS gene mutations
      LP451925-4
      • Component Numerator
        KRAS gene mutations
        LP451925-4
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    Colorectal cancer specimen
    LP222067-3
    • System Core
      Colorectal cancer specimen
      LP222067-3
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Targeted gene mutation analysis
    LP95475-7

Basic Attributes

Class
MOLPATH.MUT
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.83 (NAM)
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
85905-8Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen KRAS cílená mutační analýza:Přítomnost nebo identita:Časový bod:Vzorek kolorektálního karcinomu:Nominální:Molekulární genetika
el-GRGreek (Greece)Γονίδιο KRAS στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μοριακή γενετική
Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Γονίδιο Γονίδιο KRAS Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων
es-MXSpanish (Mexico)Análisis de mutaciones dirigidas al gen KRAS:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Genética molecular
es-ESSpanish (Spain)Gen KRAS Analisis de mutaciones:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Genética molecular
fr-FRFrench (France)KRAS gène mutation cible trouvée:Identification:Ponctuel:Tissu cancer colorectal:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)KRAS, gene analisi di mutazione mirata:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Molgen
Synonyms: Campione di tumore Gene KRAS Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio)
pl-PLPolish (Poland)KRAS gen ukierunkowana analiza mutacji:obecność lub identyfikacja:punkt w czasie:materiał z raka jelita grubego:skala nominalna:genetyka molekularna
Synonyms: Analiza mutacji genu KRAS diagnostyka molekularna Gen KRAS nowotwór wynik kategorialny
zh-CNChinese (China)KRAS2 基因 突变分析:存在与否或特征标识:时间点:结直肠癌标本:名义型:分子遗传学类实验室方法
Synonyms: Kirsten 大鼠肉瘤病毒 2;RASK1;RASK2;V-KI-RAS1 假基因;V-KI-RAS1 拟基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性致癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒癌基因同源基因;癌基因 KRAS1;癌基因 KRAS2;致癌基因 KRAS1;致癌基因 KRAS2 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 受检物 基因突变分析 存在;存在与否;特征标识;身份;身份标识 时刻;随机;随意;瞬间 样品 样本 癌 癌（癌症、癌变）标本（样本、样品、试样） 结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本 试样 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85509-8