85787-0

Vancomycin resistance vanA + vanB genes [Presence] by NAA with non-probe detection in Positive blood culture

Discouraged

Status Information

Status: DISCOURAGED
Comment: Recommend using the term with System Isolate/Specimen and Method Molgen that aligns with the new LOINC model for molecular resistance testing that was approved by Laboratory LOINC Committee in June 2018

Map-To	Long Common Name	Mapping Guidance
62261-3	Vancomycin resistance vanA + vanB genes [Presence] by Molecular method

Term Description

Qualitative detection of the nucleic acid sequences in the bacterial vancomycin resistance vanA and/or vanB genes in positive blood culture specimens by target amplification and non-probe detection methods, such as melt curve analysis. This assay detects the presence of vanA and/or vanB genes and cannot distinguish between the two. This term was created for, but not limited in use to, the submitter's test kit, FilmArray Blood Culture Identification panel v2.

Part Descriptions

LP105141-8 Bacterial vancomycin resistance vanA+vanB genes
This test is used for the detection of vancomycin resistance genes by multiplex PCR. Vancomycin is a glycopeptide antibiotic used to treat various infections, primarily those caused by gram-positive bacteria. Vancomycin resistance genes were first found in enterococci, and more recently have been found in Staphylococcus aureus. The emergence of vancomycin-resistant enterococci (VRE) and vancomycin-resistant Staphylococcus aureus (VRSA) in hospitalized patients has lead to a restricted use of vancomycin. To date, multiple vancomycin resistance genes have been characterized, including: vanA, vanB, vanC (vanC-1, vanC-2, vanC-3), and VanD. Of the six van types, vanA and vanB are the most resistant to vancomycin, and are the two types that cause VRSA. PMID: 24983424 Source: Regenstrief LOINC

LP265773-4 Bacterial ABXBACT probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

LP265774-2 Bacterial ABXBACT non-probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial vancomycin resistance vanA+vanB genes:PrThr:Pt:Bld.pos growth:Ord:Non-probe.amp.tar
Long Common Name: Vancomycin resistance vanA + vanB genes [Presence] by NAA with non-probe detection in Positive blood culture
Short Name: vanA+vanB Bld Pos Ql NAA+n-prb
Display Name: Vancomycin resistance vanA + vanB genes NAA+non-probe Ql (Pos bld culture)
Consumer Name Alpha Get Info: Vancomycin resistance vanA + vanB genes, Infected blood

Part Model Get Info

Component
Bacterial vancomycin resistance vanA+vanB genes
LP105141-8
- Analyte
  Bacterial vancomycin resistance vanA+vanB genes
  LP105141-8
  - Component Numerator
    Bacterial vancomycin resistance vanA+vanB genes
    LP105141-8
    - Component Numerator Core
      Bacterial vancomycin resistance vanA+vanB genes
      LP105141-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld.pos growth
LP183539-8
- System Core
  Bld.pos growth
  LP183539-8
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Non-probe.amp.tar
LP208998-7

Example Answer List: LL4046-0

Source: BioFire Diagnostics LLC

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8
N/A			LA4543-0

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.82 (MIN)
Change Reason: Removed parentheses from Component because the contents represent gene names, not acronyms.
Order vs. Observation: Both
Common Test Rank Get Info: 4696

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Geny vanA+vanB bakteriální rezistence na vankomycin:Přítomnost nebo práh:Časový bod:Krev pozitivní kultivace:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
de-DE	German (Germany)	Bakterielle Vancomycin-Resistenz vanA + vanB-Gene:Nachweis oder Schwellenwert:Zeitpunkt:Blut.positives Wachstum:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
el-GR	Greek (Greece)	Γονίδια vanA+ vanB βακτηριακής ανθεκτικότητας στη βανκομυκίνη:PrThr:Pt:Αίμα.θετική ανάπτυξη:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου Synonyms: ABXBACT Ord PrThr Pt Αίμα Αίμα.θετική ανάπτυξη Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Βανκομυκίνη Γονίδια vanA+ vanB βακτηριακής ανθεκτικότητας στη βανκομυκίνη Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Gen de resistencia a vancomicina:PrThr:Punto temporal:Sangre crecimiento positivo:Ord:Amplificación del objetivo no basado en sonda
es-MX	Spanish (Mexico)	Resistencia bacteriana a la vancomicina vanA + genes vanB:Presencia o umbral:Punto temporal:Hemocultivo positivo:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-FR	French (France)	Résistance bactérienne à la vancomycine gènes vanA+vanB:Présence/Seuil:Ponctuel:Hémoculture positive:Qualitatif:Non-PCR amplification de cible
it-IT	Italian (Italy)	Resistenza batterica a vancomicina (vanA+vanB), geni:PrThr:Pt:Emocolture positive:Ord:Non-sonda.amp.tar Synonyms: Amplificazione target non basata su sonda Geni di resistenza batterica a vancomicina (vanA + Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
pl-PL	Polish (Poland)	Oporność bakterii na wankomycynę vanA+vanB geny:granica wykrywalności:punkt w czasie:krew.dodatni posiew:uporządkowany:bez sondy.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy dodatni posiew krwi Geny vanA i vanB oporności bakterii na wankomycynę;Geny vanA i vanB warunkujące oporność bakterii na wankomycynę
zh-CN	Chinese (China)	细菌万古霉素耐药 vanA+vanB 基因:存在情况或阈值:时间点:血液.生长阳性:序数型:非探针法.基因扩增.靶向 Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向分子病理学 - 基因类基因存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）扩增型扩增性抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间电阻细菌万古霉素耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型）vanA+vanB 基因细菌性细菌的经过扩增的耐性脱氧核糖核酸探针血;血液血液.阳性生长;血培养阳性;阳性血培养;阳性血液培养;全血.生长阳性阻力

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.