86220-1

Carbapenem resistance blaOXA-48 gene [Presence] in Specimen by NAA with probe detection

Discouraged

Status Information

Status: DISCOURAGED
Comment: Recommend using the term with System Isolate/Specimen and Method Molgen that aligns with the new LOINC model for molecular resistance testing that was approved by Laboratory LOINC Committee in June 2018

Map-To	Long Common Name	Mapping Guidance
85503-1	Carbapenem resistance blaOXA-48 gene [Presence] by Molecular method

Part Descriptions

LP248468-3 Bacterial carbapenem resistance blaOXA-48 gene
The OXA-48 gene encodes one of the three primary classes of beta-lactamase produced by Enterobacteriaceae. OXA-48 is mainly harbored in Klebsiella pneumoniae and occurs mainly in North Africa and Turkey. It has been identified in both nosocomial and community-acquired infections. PMID: 24930781 OXA-48 is a member of the OXA group of class D beta-lactamases which includes six subgroups that are able to hydrolyze carbapenem in different degrees and of which OXA-48 is a member. PMID: 24696435 Carbapenems are the most effective treatment against bacteria that produce ESBLs. PMID: 18495062 Source: Regenstrief LOINC

LP265773-4 Bacterial ABXBACT probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial carbapenem resistance blaOXA-48 gene:PrThr:Pt:XXX:Ord:Probe.amp.tar
Long Common Name: Carbapenem resistance blaOXA-48 gene [Presence] in Specimen by NAA with probe detection
Short Name: blaOXA-48 Spec Ql NAA+probe
Display Name: Carbapenem resistance blaOXA-48 gene NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: Carbapenem resistance blaOXA-48 gene, Specimen

Part Model Get Info

Component
Bacterial carbapenem resistance blaOXA-48 gene
LP248468-3
- Analyte
  Bacterial carbapenem resistance blaOXA-48 gene
  LP248468-3
  - Component Numerator
    Bacterial carbapenem resistance blaOXA-48 gene
    LP248468-3
    - Component Numerator Core
      Bacterial carbapenem resistance blaOXA-48 gene
      LP248468-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL3713-6

Source: Mercy Genesis

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8
EquivocalCopyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value)			LA11885-3
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.69 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen blaOXA-48 bakteriální rezistence na karbapenemy:Přítomnost nebo práh:Časový bod:XXX:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-AT	German (Austria)	Synonyms: Carbapenem Resistenz Gen (blaOXA-48) ql.
de-DE	German (Germany)	Bakterielle Carbapenem-Resistenz blaOXA-48-Gen:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Γονίδιο blaOXA-48 βακτηριακής ανθεκτικότητας στις καρβαπενέμες:PrThr:Pt:XXX:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: ABXBACT Ord PrThr Pt XXX Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Γονίδιο Γονίδιο blaOXA-48 βακτηριακής ανθεκτικότητας στις καρβαπενέμες Καρβαπενέμη
es-ES	Spanish (Spain)	gen bacteriano blaOXA-48 resistente a carbapenem:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	Gen blaOXA-48 de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Résistance bactérienne aux carbapénèmases gène blaOXA-48:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Resistenza batterica ai carbapenemici, gene blaOXA-48:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Gene blaOXA-48 di resistenza batterica ai carbapenemi Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële carbapenemresistentie blaOXA-48-gen:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: bacterial carbapenem resistentie blaOXA-48 gen probe.amp.tar
pl-PL	Polish (Poland)	Gen blaOXA-48 oporności bakteryjnej na karbapenemy:granica wykrywalności:punkt w czasie:XXX:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Antybiotyk karbapenemowy
zh-CN	Chinese (China)	细菌碳青霉烯类耐药 blaOXA-48 基因:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）扩增型扩增性抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间电阻碳青霉烯类;碳青霉烯类抗生素细菌性细菌的细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaOXA-48 基因经过扩增的耐性脱氧核糖核酸探针遗传基因;遗传因子;吉恩;生物基因阻力

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.