Version 2.72

88038-5Hy Ab [Presence] in Serum or PlasmaActive

Part Descriptions

LP264211-6   H little y
The first example of anti-Doa, reactive with 64% of the Caucasian population, was reported by Swanson et al. in 1965. It was not until 1972 that Molthan et al. reported the antithetical antibody anti-Dob. Thus, the Dombrock blood group system was defined and was estimated to be the fifth most useful blood group marker in Caucasians. However, limited examples of both antibodies greatly restricted broad investigations. The Dombrock system remained a simple two allele system until 1992, when Banks et al. reported that the red cells of the rare Gy(a-) Hy(a-) Jo(a-) individuals were also Do(a-b-). Consequently, these three high incidences blood factors were included within the system. Interestingly, it had already been known that all Gy(a-) red cells lacked both Hya and Joa antigens and that Hy(a-) red cells lacked Joa antigens. Ironically, Swanson reported the first examples of both anti-Doa (in 1965) and anti-Gya (1967) but as anti-Dob was, at that time, yet to be discovered any association with Doa and Gya could not be deduced. Source: Serum, Cells and Rare Fluid Exchange, Dombrock group

LP264211-6   H little y
The Hy antigen is one of eight members of the Dombrock blood group system. The Hy antigen is only commonly expressed in people with African ancestry and never seen in caucasians. Because the supply for antisera to Dombrock antigens is very limited and have weak reactions with Dombrock antigens, compatibility testing is best done by single nucleotide polymorphism methods. The two antibodies anti-Doa and anti-Dob have caused acute and delayed hemolytic transfusion reactions. There is little clinical information about the other Dombrock antibodies other than that none have caused hemolytic disease of the newborn. [AABB Technical Manual, 18th edition, pp354-355] Source: Regenstrief LOINC, Dombrock group

Fully-Specified Name

H little y Ab

Additional Names

Short Name
Hy Ab SerPl Ql
Display Name
Hy Ab Ql
Consumer Name Alpha
Hy antibody, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.63
Last Updated
Version 2.64
Change Reason
The short and long names were updated for consistency across blood bank terms.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
Hy 抗体:存在情况或阈值:时间点:血清/血浆:序数型:
fr-FRFrench (France)
Hy anticorps:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
it-ITItalian (Italy)
H y minuscola Ab:PrThr:Pt:Siero/Plasma:Ord:
es-MXSpanish (Mexico)
H poco y Ab:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:
es-ESSpanish (Spain)
Hy Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:

LOINC FHIR® API Example - CodeSystem Request Get Info