88215-9

Rabies virus RNA [Presence] in Saliva (oral fluid) by NAA with probe detection

Active

Part Descriptions

LP16737-6   Rabies virus
Rabies virus (RV), is an enveloped, single-stranded, negative sense RNA virus and a member of the Rhabdoviridae family. It is transmitted when an animal infected with RV bites an individual or the saliva from an infected animal comes into contact with an open wound. Once RV penetrates the muscle or connective tissue it begins to replicate and then infiltrates the peripheral nerves through the neuromuscular junction. From there, RV spreads to the central nervous system (CNS) in the endoneurium of the Schwann cells. If bitten by an animal that may have RV infection, rabies immune globulin and rabies vaccine should be administered. Otherwise, there is no treatment for infection by RV other than supportive care, and acute infection of the CNS is almost always fatal. In countries where preventative care is not practiced, RV is still widespread. In Asia, 30,000 people die annually from RV infection. Diagnosis of RV is done on two tissue specimens from the brain that are analyzed by direct fluorescent antibody (DFA), mouse inoculation, tissue culture and polymerase chain reaction.[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307483/] Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

Fully-Specified Name

Component

Rabies virus RNA

Property

PrThr

Time

Pt

System

Saliva

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

RABV RNA Sal Ql NAA+probe

Display Name

Rabies virus RNA NAA+probe Ql (Sal)

Consumer Name Alpha Get Info

Rabies virus, Saliva

Example Answer List: LL744-4

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.63

Last Updated

Version 2.63

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• DNA NUCLEIC ACID PROBE
• DNA probe
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Lyssavirus
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Oral fluid
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Rabies
• RABV
• Random
• Ribonucleic acid
• Sal
• Screen
• SDA
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

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