88601-0
Influenza virus types A and B panel - Lower respiratory specimen by NAA with probe detection
Active
88599-6 Influenza virus A RNA [Presence] in Lower respiratory specimen by NAA with probe detection
Part Descriptions
LP14239-5 Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock)
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus A RNA
- Property
- PrThr
- Time
- Pt
- System
- Respiratory system specimen.lower
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- FLUAV RNA Lower resp Ql NAA+probe
- Display Name
- FLUAV RNA NAA+probe Ql (Lower resp)
- Consumer Name Alpha Get Info
- Influenza A (Flu A), Lower respiratory
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.77
- Change Reason
- Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
- Order vs. Observation
- Both
Example Answer List LL744-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 88601-0 | Influenza virus types A and B panel - Lower respiratory specimen by NAA with probe detection |
| 94393-6 | Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with probe detection |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32757-3 | Influenza virus |
| LG34064-2 | Influenza virus A RNA| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Influenza-Virus A RNA: |
| es-MX | Spanish (Mexico) | ARN del virus de la influenza A: |
| es-ES | Spanish (Spain) | Virus Influenza A RNA: Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio |
| fr-FR | French (France) | Influenza virus A ARN: |
| it-IT | Italian (Italy) | Influenza A, virus RNA: Synonyms: Campione da Apparato Respiratorio Campione da apparato respiratorio inferiore Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A |
| nl-NL | Dutch (Netherlands) | Influenzavirus A RNA: Synonyms: onderste ademhalingsstelsel; |
88592-1 Influenza virus B RNA [Presence] in Lower respiratory specimen by NAA with probe detection
Part Descriptions
LP14240-3 Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus B RNA
- Property
- PrThr
- Time
- Pt
- System
- Respiratory system specimen.lower
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- FLUBV RNA Lower resp Ql NAA+probe
- Display Name
- FLUBV RNA NAA+probe Ql (Lower resp)
- Consumer Name Alpha Get Info
- Influenza B (Flu B), Lower respiratory
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.77
- Change Reason
- Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
- Order vs. Observation
- Both
Example Answer List LL744-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 88601-0 | Influenza virus types A and B panel - Lower respiratory specimen by NAA with probe detection |
| 94393-6 | Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with probe detection |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32757-3 | Influenza virus |
| LG34065-9 | Influenza virus B RNA| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Influenza-Virus B RNA: |
| es-MX | Spanish (Mexico) | ARN del virus de la influenza B: |
| es-ES | Spanish (Spain) | Virus Influenza B RNA: Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio |
| fr-FR | French (France) | Influenza virus B ARN: |
| it-IT | Italian (Italy) | Influenza B, virus RNA: Synonyms: Campione da Apparato Respiratorio Campione da apparato respiratorio inferiore Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza B |
| nl-NL | Dutch (Netherlands) | Influenzavirus B RNA: Synonyms: onderste ademhalingsstelsel; |