88926-1
Histoplasma capsulatum DNA [Presence] in Tissue by NAA with probe detection
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Part Description
LP16650-1 Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.
H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Histoplasma capsulatum DNA
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Long Common Name
- Histoplasma capsulatum DNA [Presence] in Tissue by NAA with probe detection
- Short Name
- H capsul DNA Tiss Ql NAA+probe
- Display Name
- H. capsulatum DNA NAA+probe Ql (Tiss)
- Consumer Name Alpha Get Info
- Histoplasma capsulatum, Tissue
Example Answer List: LL744-4
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.64 (ADD)
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
95918-9 | Fungal pathogens panel - Tissue by NAA with probe detection |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Histoplasma capsulatum (Ιστόπλασμα) DNA: Synonyms: DNA Histoplasma capsulatum (Ιστόπλασμα) PrThr |
es-ES | Spanish (Spain) | Histoplasma capsulatum ADN: |
es-MX | Spanish (Mexico) | ADN de Histoplasma capsulatum: |
fr-CA | French (Canada) | Histoplasma capsulatum, ADN: |
fr-BE | French (Belgium) | Histoplasma capsulatum ADN: |
fr-FR | French (France) | Histoplasma capsulatum ADN: |
it-IT | Italian (Italy) | Histoplasma capsulatum DNA: Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Tessuto & |
nl-NL | Dutch (Netherlands) | Histoplasma capsulatum DNA: Synonyms: probe.amp.tar |
ru-RU | Russian (Russian Federation) | Histoplasma capsulatum ДНК: Synonyms: ДНК проба; |
tr-TR | Turkish (Turkey) | Histoplazma Kapsulatum DNA: Synonyms: Mevcut |
zh-CN | Chinese (China) | 荚膜组织胞浆菌 DNA: Synonyms: 依次型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=88926-1
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://