Version 2.77

Part Description

LP266717-0   Fluoroquinolone
Fluorquinolones are among most beneficial drugs used to treat multi-drug resistant Mycobacterium tuberculosis (MDR-TB) infections. The fluorquinolones affect the activity of DNA gyrase by reducing the cell's ability for DNA replication and transcription. DNA gyrase in Mycobacterium tuberculosis (TB) is made of two subunits that are encoded by gyrA and gyrB. Mutations in the gyrA quinolone resistance-determining region (QRDR) are responsible for causing most of the drug resistance of TB to the fluoroquinolones. The gyrB mutations have a much smaller impact on TB resistance to the fluoroquinolones. PMID: 26763957 Source: Regenstrief LOINC

Fully-Specified Name

Component
Fluoroquinolone
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
FLQ Islt Genotyp
Display Name
Fluoroquinolone Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Fluoroquinolone

Example Answer List: LL3666-6

Source: North Carolina State Laboratory of Public Health
Answer Code Score Answer ID
Resistant LA6676-6
Susceptible LA24225-7

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.69
Change Reason
Release 2.69: SYSTEM: Updated System to "Isolate" since this concept is about the susceptibility of the viral isolate to the drug, not the susceptibility of the specimen to the drug.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
92254-2 Microorganism identification and resistance pattern determination panel by Molecular genetics method
89486-5 Mycobacterial susceptibility panel Qualitative by Genotype method
94053-6 Mycobacterium tuberculosis complex resistance panel by Molecular genetics method

Member of these Groups Get Info

LOINC Group Group Name
LG51364-4 FluoroquinoloneSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Fluorchinolon:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal:Genotypisierung
es-ES Spanish (Spain) Fluoroquinolona:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Fluoroquinolona:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Fluoroquinolone:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Fluorochinolone:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) fluorchinolon:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 氟喹诺酮:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 氟喹诺酮类抗生素;氟喹诺酮类药物

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89487-3