89487-3
Fluoroquinolone [Susceptibility] by Genotype method
Active
Part Description
LP266717-0 Fluoroquinolone
Fluorquinolones are among most beneficial drugs used to treat multi-drug resistant Mycobacterium tuberculosis (MDR-TB) infections. The fluorquinolones affect the activity of DNA gyrase by reducing the cell's ability for DNA replication and transcription. DNA gyrase in Mycobacterium tuberculosis (TB) is made of two subunits that are encoded by gyrA and gyrB. Mutations in the gyrA quinolone resistance-determining region (QRDR) are responsible for causing most of the drug resistance of TB to the fluoroquinolones. The gyrB mutations have a much smaller impact on TB resistance to the fluoroquinolones. PMID: 26763957
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Fluoroquinolone
- Property
- Susc
- Time
- Pt
- System
- Isolate
- Scale
- Ord
- Method
- Genotyping
Additional Names
- Short Name
- FLQ Islt Genotyp
- Display Name
- Fluoroquinolone Genotyping [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Fluoroquinolone
Example Answer List: LL3666-6
Source: North Carolina State Laboratory of Public HealthAnswer | Code | Score | Answer ID |
---|---|---|---|
Resistant | LA6676-6 | ||
Susceptible | LA24225-7 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.69
- Change Reason
- Release 2.69: SYSTEM: Updated System to "Isolate" since this concept is about the susceptibility of the viral isolate to the drug, not the susceptibility of the specimen to the drug.;
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
92254-2 | Microorganism identification and resistance pattern determination panel by Molecular genetics method |
89486-5 | Mycobacterial susceptibility panel Qualitative by Genotype method |
94053-6 | Mycobacterium tuberculosis complex resistance panel by Molecular genetics method |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51364-4 | FluoroquinoloneSusc| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Fluorchinolon: |
es-ES | Spanish (Spain) | Fluoroquinolona: |
es-MX | Spanish (Mexico) | Fluoroquinolona: |
fr-FR | French (France) | Fluoroquinolone: |
it-IT | Italian (Italy) | Fluorochinolone: Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale |
nl-NL | Dutch (Netherlands) | fluorchinolon: |
zh-CN | Chinese (China) | 氟喹诺酮: Synonyms: 依次型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=89487-3
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright