89505-2

Proteinase 3 Ab [Presence] in Serum by Line blot

Active

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.

Part Description

LP17259-0 Proteinase 3
Proteinase 3 (PR3) is an enzyme contained in white blood cell neutrophils. It contributes to the breakdown of microbial proteins into polypeptides or amino acids (proteolysis). Antibodies to Proteinase 3 are a subgroup of anti-neutrophil cytoplasmic antibodies that can cause the disease granulomatosis with polyangitis that affects primarily the kidneys and the lungs. PMID: 21079042 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Proteinase 3 Ab:PrThr:Pt:Ser:Ord:Line blot
Long Common Name: Proteinase 3 Ab [Presence] in Serum by Line blot
Short Name: Proteinase3 Ab Ser Ql Line blot
Display Name: Proteinase 3 Ab Line blot Ql (S)
Consumer Name Alpha Get Info: Proteinase 3 antibody, Blood

Part Model Get Info

Component
Proteinase 3 Ab
LP39491-3
- Analyte
  Proteinase 3 Ab
  LP39491-3
  - Component Numerator
    Proteinase 3 Ab
    LP39491-3
    - Component Numerator Core
      Proteinase 3
      LP17259-0
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Line blot
LP266806-1

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.64
Last Updated: Version 2.64 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG26752-2	Proteinase 3 Ab\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Proteináza 3 Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Line blot
el-GR	Greek (Greece)	Πρωτεάση 3 Αντίσωμα:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης Synonyms: Ord PrThr Pt SERO Αντίσωμα Γραμμή κηλίδωσης Ορός Πρωτεάση 3
es-ES	Spanish (Spain)	Proteinasa 3 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX	Spanish (Mexico)	Proteinasa 3 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FR	French (France)	Protéinase 3 Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
fr-CA	French (Canada)	Protéinase 3, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
it-IT	Italian (Italy)	Proteinasi 3 Ab:PrThr:Pt:Siero:Ord:Line blot Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	proteïnase 3 As:aanwezigheid:moment:serum:ordinaal:lijnblot Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Proteinaza 3 Ab:granica wykrywalności:punkt w czasie:surowica:uporządkowany:line blot
zh-CN	Chinese (China)	蛋白酶 3 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法 Synonyms: Ⅲ Ab;自身抗体 III PR3 Ab PR-3 Ab PR3 抗体 PR-3 抗体 PR3;PR-3;PR3-ANCA 三依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型叁存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间线点杂交技术;线点杂交法;线条状印迹法蛋白酶 3 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.