Version 2.78

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ag
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
VZV Ag CSF Ql IF
Display Name
VZV Ag IF Ql (CSF)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) antigen, Spinal fluid

Example Answer List: LL1937-3

Source: 3M Health Information Systems
Answer Code Score Answer ID
PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value) LA9633-4
AbsentCopyright http://snomed.info/sct ID:2667000 Absent (qualifier value) LA9634-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Varicella-Zoster-Virus Ag:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Immunfluoreszenztest
Synonyms: Human alphaherpesvirus 3; VZV; Zerebrospinalflüssigkeit
es-ES Spanish (Spain) Virus Varicella zoster Antígeno:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Virus de la varicela zóster Ag:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Tuulerõugeviirus antigeen:PrThr:Pt:CSF:Ord:IF
Synonyms: Järgarvuline Juhuslik Liikvor
fr-CA French (Canada) Virus varicelle-zona, Ag:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunofluorescence
fr-BE French (Belgium) Virus varicelle-zona Ag:PrThr:Temps ponctuel:LCR:Ordinal:Immunofluorescence
Synonyms: Antigène VZV
fr-FR French (France) Varicelle zona virus Ag:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Varicella zoster, virus, Ag:PrThr:Pt:LCS:Ord:IF
Synonyms: Immunofluorescenza (IF) Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Virus della varicella zoster
nl-NL Dutch (Netherlands) varicella-zostervirus Ag:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunofluorescentie
Synonyms: antigeen IF Varicella zoster virus
ru-RU Russian (Russian Federation) Varicella zoster вирус Аг:PrThr:ТчкВрм:ЦСЖ:Пор:ИФ
Synonyms: Иммунофлюоресценция (ИФ) Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Varicella zoster virüsü Ag:MevcEşik:Zmlı:BOS:Srl:IF
Synonyms: Antijen İmmünflorerans Mevcut
zh-CN Chinese (China) 水痘带状疱疹病毒 抗原:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
Synonyms: Ag Ag IF CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 DFA HHV-3 Ag HHV-3 抗原 HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 VZV Ag VZV 抗原 人类疱疹病毒 3 型 Ag 人类疱疹病毒 3 型抗原 人类疱疹病毒 III 型 Ag 人类疱疹病毒 III 型抗原 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗原免疫荧光检测 抗原免疫荧光测定 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ag 水痘病毒 Ag 水痘病毒抗原 直接免疫荧光分析 直接免疫荧光检测 直接免疫荧光测定 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89589-6