Version 2.77

Part Description

LP157352-8   Mycobacterium leprae
Mycobacterium leprae is the bacterium that causes leprosy. Leprosy is a chronic illness that affects the skin, peripheral nerves, eyes and mucosa of the upper respiratory tract. Infection with Mycobacterium leprae causes numbness, nerve damage, disfigurement of limbs and tissue decay. M. leprae was discovered in 1873 by Armauer Hansen in Bergen, Norway and was the first organism to be associated with a human disease. It is an acid fast rod shaped obligate intracellular bacterium. It is drawn to macrophages and especially Schwann cells of the peripheral nerves. It is difficult to culture in vitro which has impeded an understanding of how it is transmitted, in what environment it resides and why infected individuals have such different clinical outcomes. Treatment involves monthly rifampicin and dapsone and clofazimine on a daily basis for 12 months. Drug resistance testing is mostly molecular and focuses on specific mutations associated with drug resistance.[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076554/] Source: Regenstrief LOINC

Fully-Specified Name

Component
Mycobacterium leprae DNA
Property
PrThr
Time
Pt
System
Respiratory system specimen.upper
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
M leprae DNA Upper resp Ql NAA+probe
Display Name
Mycobacterium leprae DNA NAA+probe Ql (Upper resp)
Consumer Name Alpha Get Info
Mycobacterium leprae, Upper respiratory

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.77
Change Reason
Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG51619-1 Mycobacterium leprae

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Mycobacterium leprae DNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom oberen Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) ADN de Mycobacterium leprae:Presencia o umbral:Punto temporal:Muestra respiratoria superior:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Mycobacterium leprae ADN:Présence/Seuil:Ponctuel:Voies respiratoires supérieures:Qualitatif:PCR amplification de cible
nl-NL Dutch (Netherlands) Mycobacterium leprae DNA:aanwezigheid:moment:bovenste luchtwegen:ordinaal:probe-detectie
Synonyms: bovenste ademhalingsstelsel; systema respiratorium superior probe.amp.tar systema respiratorium; ademhalingsstelsel

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=91805-2