Version 2.78

Part Descriptions

LP16659-2   Mycobacterium tuberculosis
Mycobacterium tuberculosis was discovered by Robert Koch in 1882 to be the infectious organism of tuberculosis (TB). Tuberculosis is a worldwide public health problem, especially in third world countries. The infection is classified as latent when the patient is asymptomatic and the infection is in a non-transmissible state. The active form of TB is transmissible and can be diagnosed by culturing the organism or by using molecular testing. Patients who are symptomatic have symptoms including fever, fatigue, loss of appetite, weight loss, persistent cough, and hemoptysis. Treatment of TB has been complicated by the emergence of drug-resistant strains which are present all over the world. Resistance to all of the drugs used to treat TB has occurred including the first line of treatment drugs isoniazid, rifampicin, pyrazinamide, and ethambutol. Some strains of TB have become resistant to more than one of the drugs used to treat TB, and are referred to as either multidrug-resistant TB (MDR-TB) or extensively drug-resistant TB (XDR-TB). MDR-TB are defined to be resistant to at least isoniazid and rifampicin. XDR-TB have worse disease symptoms and are resistant to isoniazid, rifampicin, any one of the fluoroquinolones, and any one of the three injectable second-line drugs amikacin, kanamycin, and capreomycin. The biggest risk factor for acquiring TB is to be infected by the human immunodeficiency virus (HIV). Twenty-five percent of all TB infections occur in patients also infected with HIV, and most of those occur in Africa. Social and behavioral determinants such as excessive alcohol use, smoking, and type 2 diabetes mellitus can increase the risk of contracting TB by two to three times.[https://www.nature.com/articles/nrdp201676] Source: Regenstrief LOINC

LP16659-2   Mycobacterium tuberculosis
Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis (TB). M. tuberculosis has an unusual, waxy coating on its cell surface (primarily mycolic acid), which makes the cells impervious to Gram staining, so acid-fast detection techniques are used, instead. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, MTB infects the lungs. The most frequently used diagnostic methods for TB are the tuberculin skin test, acid-fast stain, and chest radiographs Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mycobacterium tuberculosis (Wikipedia)

LP16659-2   Mycobacterium tuberculosis
A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Mycobacterium tuberculosis DNA
Property
PrThr
Time
Pt
System
Respiratory system specimen.lower
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
M tb DNA Lower resp Ql NAA+probe
Display Name
M. tuberculosis DNA NAA+probe Ql (Lower resp)
Consumer Name Alpha Get Info
Mycobacterium tuberculosis, Lower respiratory

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.77
Change Reason
Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94393-6 Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG33989-1 Mycobacterium tuberculosis DNA|PrThr|Sys:ANYResp

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Mycobacterium tuberculosis DNA:Nachweis oder Schwellenwert:Zeitpunkt:Respirationstrakt.unterer:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) ADN de Mycobacterium tuberculosis:Presencia o umbral:Punto temporal:Muestra de vías respiratorias inferiores:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Mycobacterium tuberculosis ADN:PrThr:Punto temporal:Muestra de vías respiratorias inferiores:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-FR French (France) Mycobacterium tuberculosis ADN:Présence/Seuil:Ponctuel:Voies respiratoires inférieures:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Mycobacterium tuberculosis DNA:PrThr:Pt:Campione da Sistema Respiratorio.inferiore:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Campione da apparato respiratorio inferiore Micobatterio della tubercolosi Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Mycobacterium tuberculosis DNA:aanwezigheid:moment:onderste luchtwegen:ordinaal:probe-detectie
Synonyms: onderste ademhalingsstelsel; systema respiratorium inferior probe.amp.tar systema respiratorium; ademhalingsstelsel

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=91829-2