91829-2

Mycobacterium tuberculosis DNA [Presence] in Lower respiratory specimen by NAA with probe detection

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Part Descriptions

LP16659-2 Mycobacterium tuberculosis
Mycobacterium tuberculosis was discovered by Robert Koch in 1882 to be the infectious organism of tuberculosis (TB). Tuberculosis is a worldwide public health problem, especially in third world countries. The infection is classified as latent when the patient is asymptomatic and the infection is in a non-transmissible state. The active form of TB is transmissible and can be diagnosed by culturing the organism or by using molecular testing. Patients who are symptomatic have symptoms including fever, fatigue, loss of appetite, weight loss, persistent cough, and hemoptysis. Treatment of TB has been complicated by the emergence of drug-resistant strains which are present all over the world. Resistance to all of the drugs used to treat TB has occurred including the first line of treatment drugs isoniazid, rifampicin, pyrazinamide, and ethambutol. Some strains of TB have become resistant to more than one of the drugs used to treat TB, and are referred to as either multidrug-resistant TB (MDR-TB) or extensively drug-resistant TB (XDR-TB). MDR-TB are defined to be resistant to at least isoniazid and rifampicin. XDR-TB have worse disease symptoms and are resistant to isoniazid, rifampicin, any one of the fluoroquinolones, and any one of the three injectable second-line drugs amikacin, kanamycin, and capreomycin. The biggest risk factor for acquiring TB is to be infected by the human immunodeficiency virus (HIV). Twenty-five percent of all TB infections occur in patients also infected with HIV, and most of those occur in Africa. Social and behavioral determinants such as excessive alcohol use, smoking, and type 2 diabetes mellitus can increase the risk of contracting TB by two to three times.https://www.nature.com/articles/nrdp201676 Source: Regenstrief LOINC

LP16659-2 Mycobacterium tuberculosis
Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis (TB). M. tuberculosis has an unusual, waxy coating on its cell surface (primarily mycolic acid), which makes the cells impervious to Gram staining, so acid-fast detection techniques are used, instead. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, MTB infects the lungs. The most frequently used diagnostic methods for TB are the tuberculin skin test, acid-fast stain, and chest radiographs Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mycobacterium tuberculosis (Wikipedia)

LP16659-2 Mycobacterium tuberculosis
A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name: Mycobacterium tuberculosis DNA:PrThr:Pt:Respiratory system specimen.lower:Ord:Probe.amp.tar
Long Common Name: Mycobacterium tuberculosis DNA [Presence] in Lower respiratory specimen by NAA with probe detection
Short Name: M tb DNA Lower resp Ql NAA+probe
Display Name: M. tuberculosis DNA NAA+probe Ql (Lower resp)
Consumer Name Alpha Get Info: Mycobacterium tuberculosis, Lower respiratory

Part Model Get Info

Component
Mycobacterium tuberculosis DNA
LP39077-0
- Analyte
  Mycobacterium tuberculosis DNA
  LP39077-0
  - Component Numerator
    Mycobacterium tuberculosis DNA
    LP39077-0
    - Component Numerator Core
      Mycobacterium tuberculosis
      LP16659-2
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Respiratory system specimen.lower
LP438102-8
- System Core
  Respiratory system specimen.lower
  LP438102-8
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.66
Last Updated: Version 2.77 (MAJ)
Change Reason: Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
94393-6	Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG33989-1	Mycobacterium tuberculosis DNA\|PrThr\|Sys:ANYResp

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Mycobacterium tuberculosis DNA:Přítomnost nebo práh:Časový bod:Vzorek dolních cest dýchacích:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Mycobacterium tuberculosis DNA:Nachweis oder Schwellenwert:Zeitpunkt:Respirationstrakt.unterer:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Mycobacterium tuberculosis (Μυκοβακτηρίδιο της φυματίωσης) DNA:PrThr:Pt:Δείγμα αναπνευστικού συστήματος.κατώτερο:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: DNA MICRO Mycobacterium tuberculosis (Μυκοβακτηρίδιο της φυματίωσης) Ord PrThr Pt Αναπνευστικό Αναπνευστικό σύστημα Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Δείγμα Δείγμα αναπνευστικού συστήματος Δείγμα αναπνευστικού συστήματος.κατώτερο
es-MX	Spanish (Mexico)	ADN de Mycobacterium tuberculosis:Presencia o umbral:Punto temporal:Muestra de vías respiratorias inferiores:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES	Spanish (Spain)	Mycobacterium tuberculosis ADN:PrThr:Punto temporal:Muestra de vías respiratorias inferiores:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-FR	French (France)	Mycobacterium tuberculosis ADN:Présence/Seuil:Ponctuel:Échantillon du système respiratoire inférieur:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Mycobacterium tuberculosis DNA:PrThr:Pt:Campione da Sistema Respiratorio.inferiore:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Campione da apparato respiratorio inferiore Micobatterio della tubercolosi Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Mycobacterium tuberculosis DNA:aanwezigheid:moment:onderste luchtwegen:ordinaal:probe-detectie Synonyms: onderste ademhalingsstelsel; systema respiratorium inferior probe.amp.tar systema respiratorium; ademhalingsstelsel
pl-PL	Polish (Poland)	Mycobacterium tuberculosis DNA:granica wykrywalności:punkt w czasie:próbka z układu oddechowego.dolna część:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Kwas deoksyrybonukleinowy Prątek gruźlicy próbka z dolnych dróg układu oddechowego
zh-CN	Chinese (China)	结核分枝杆菌 DNA:存在情况或阈值:时间点:呼吸系统标本.下:序数型:探针法.基因扩增.靶向 Synonyms: AFB 下下的下部低级低级的供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向分支杆菌分支杆菌属分枝杆菌属劳瘵去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）受检物呼吸系统（呼吸道）标本.下;下呼吸系统标本;下呼吸道标本呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性抗酸抗酸杆菌抗酸杆菌（Acid fast bacillus，AFB）抗酸菌时刻;随机;随意;瞬间样品样本痨痨病经过扩增的结核结核;肺结核;痨;痨病;TB 结核分支杆菌 DNA 结核分支杆菌;结核杆菌;结核菌结核病肺结核脱氧核糖核酸探针试样较低较低的

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.