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Part Descriptions

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Hepatitis C virus genotype:Type:Pt:Ser/Plas:Nom:Sequencing
Long Common Name
Hepatitis C virus genotype in Serum or Plasma by Sequencing
Short Name
HCV Gentyp SerPl Seq
Display Name
HCV genotype Sequencing
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) genotype, Blood

Part Model Get Info

  • Component
    Hepatitis C virus genotype
    LP174046-5
    • Analyte
      Hepatitis C virus genotype
      LP174046-5
      • Component Numerator
        Hepatitis C virus genotype
        LP174046-5
        • Component Numerator Core
          Hepatitis C virus
          LP14400-3
        • Component Numerator Core Suffix
          genotype
          LP29254-7
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Type
    LP6886-8
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Sequencing
    LP150045-5

Preferred Answer List: LL2254-2

Source: Regenstrief LOINC
AnswerCodeScoreAnswer ID
1LA6112-2
2 or moreLA6113-0
3LA6114-8
4LA6115-5
5LA10137-0
6LA10138-8
Not detectedLA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.72 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
82525-7Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC GroupGroup Name
LG32754-0Hepatitis C virus

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)تحديد النمط الجيني لفيروس التهاب الكبد الوبائي نمط C في المصل أو البلازما ( بتقنية التسلسل )
cs-CZCzech (Czechia)Virus hepatitidy C genotyp:Typ:Časový bod:Sérum/plazma:Nominální:Sekvenace
de-DEGerman (Germany)Hepatitis-C-Virus Genotyp:Typ:Zeitpunkt:Serum oder Plasma:Nominal:Sequenzierung
Synonyms: Hepacivirus C; HCV
el-GRGreek (Greece)Ιός Ηπατίτιδας C γονότυπος:Type:Pt:Ορός/Πλάσμα:Nom:Αλληλούχιση
Synonyms: C MICRO Nom Pt Type Αλληλούχιση γονότυπος Ιός Ιός ηπατίτιδας C Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)Virus Hepatitis C Genotipo:Tipo:Punto temporal:Suero o Plasma:Nom:Secuenciación
es-MXSpanish (Mexico)Genotipo del virus de la hepatitis C:Tipo:Punto temporal:Suero o Plasma:Nominal:Secuenciación
fr-BEFrench (Belgium)Virus de l'hépatite C Génotype:Type:Temps ponctuel:Sérum/Plasma:Nominal:Séquençage
Synonyms: Génotype HCV
fr-FRFrench (France)Hépatite C virus génotype:Type:Ponctuel:Sérum/Plasma:Résultat nominal:Séquençage
fr-CAFrench (Canada)Virus de l'hépatite C, Génotype:Type:Temps ponctuel:Sérum/Plasma:Nominal:Séquençage
it-ITItalian (Italy)Epatite C, virus, genotipo:Tipo:Pt:Siero/Plasma:Nom:Sequenziamento
Synonyms: Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Virus dell''epatite C
nl-NLDutch (Netherlands)Hepatitis C-virus genotype:type:moment:serum of plasma:nominaal:sequencing
pl-PLPolish (Poland)Wirus zapalenia wątroby typu C genotyp:typ:punkt w czasie:surowica lub osocze:skala nominalna:sekwencjonowanie
Synonyms: Genotyp wirusa zapalenia wątroby typu C wynik kategorialny
tr-TRTurkish (Turkey)Hepatit C virüsü genotip:Tip:Zmlı:Ser/Plaz:Snf:Sekanslama
Synonyms: Dizi tayini Tür
zh-CNChinese (China)丙型肝炎病毒 基因型:类型:时间点:血清/血浆:名义型:序列测定
Synonyms: C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 型 属模标本;遗传型 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 肝 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92731-9