93390-3

Carbapenem resistance blaOXA-23-like+blaOXA-48-like genes [Presence] in Isolate or Specimen by Molecular method

Active

Term Description

This test detects but does not differentiate between the OXA-23 and OXA-48 groups, which both confer carbapenem resistance. This term was created for, but not limited in use to, the blaOXA antimicrobial resistant marker result in GeneMark's ePlex Blood Culture Identification Gram-Negative Panel.

Part Description

LP411469-2 Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
The Ambler classification for carbapenemases utilizes four molecular classes - A, B, C and D. The OXA group of β-lactamases occur mainly in Acinetobacter species and are part of molecular class D. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. PMID: 24696435. Many OXA enzymes (OXA-23-like, OXA-24-like, OXA-48-like, OXA-58-like) are considered to be responsible for the worldwide resistance epidemics. OXA-23-like enzymes have been isolated in carbapenem-resistant Acinetobacter baumannii (CR-AB) in both the US and in China, revealing the importance of national and global efforts to control the spread of CR-AB.
PMID: 24629777 PMID: 26617588 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes:PrThr:Pt:Isolate/Specimen:Ord:Molgen
Long Common Name: Carbapenem resistance blaOXA-23-like+blaOXA-48-like genes [Presence] in Isolate or Specimen by Molecular method
Short Name: blaOXA-23+48-like genes Islt/Spm Ql
Display Name: Carbapenem resistance blaOXA-24-like+blaOXA-48-like genes Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info: Carbapenem resistance blaOXA-24-like+blaOXA-48-like genes

Part Model Get Info

Component
Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
LP411469-2
- Analyte
  Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
  LP411469-2
  - Component Numerator
    Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
    LP411469-2
    - Component Numerator Core
      Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
      LP411469-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate/Specimen
LP266970-5
- System Core
  Isolate/Specimen
  LP266970-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Molgen
LP6404-0

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.67
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
97324-8	Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
85502-3	Carbapenemase resistance genes panel by Molecular genetics method
93407-5	Gram negative blood culture panel by NAA with probe detection in Positive blood culture

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Geny blaOXA-24-like+blaOXA-48-like bakteriální rezistence na karbapenemy:Přítomnost nebo práh:Časový bod:Izolát/vzorek:Ordinální:Molekulární genetika
de-DE	German (Germany)	Bakterielle Carbapenem-Resistance blaOXA-23-ähnliches+blaOXA-48-ähnliches Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
el-GR	Greek (Greece)	Γονίδια τύπου blaOXA-23+blaOXA-48 βακτηριακής ανθεκτικότητας στις καρβαπενέμες:PrThr:Pt:Απομονωθέν στέλεχος/Δείγμα:Ord:Μοριακή γενετική Synonyms: MICRO Ord PrThr Pt Απομονωθέν στέλεχος/Δείγμα Απομονωμένο στέλεχος Γονίδια τύπου blaOXA-23+blaOXA-48 βακτηριακής ανθεκτικότητας στις καρβαπενέμες Δείγμα Καρβαπενέμη Μοριακή γενετική
es-ES	Spanish (Spain)	Genes de resistencia a los carbapenémicos bacterianos similares a blaOXA-23 + similares a blaOXA-48:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX	Spanish (Mexico)	Resistencia a los carbapenémicos bacterianos genes similares a blaOXA-23 + genes similares a blaOXA-48:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR	French (France)	Résistance bactérienne aux carbapénèmases gènes blaOXA-23-like+blaOXA-48-like:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	Resistenza batterica ai carbapenemici, geni blaOXA-23-like+blaOXA-48-like:PrThr:Pt:Isolato/Campione:Ord:Molgen Synonyms: Genetica molecolare Geni blaOXA-24-like+blaOXA-48-like di resistenza batterica ai carbapenemi Isolato o Campione Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	bacteriële carbapenemresistentie blaOXA-23-achtig + blaOXA-48-achtig genen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek Synonyms: blaOXA-134-like isolaat/specimen molgen
pl-PL	Polish (Poland)	Geny blaOXA-23-like+blaOXA-48-like bakteryjnej oporności na karbapenemy:granica wykrywalności:punkt w czasie:szczep/izolat lub próbka:uporządkowany:genetyka molekularna Synonyms: Antybiotyk karbapenemowy diagnostyka molekularna Geny blaOXA-23-like i blaOXA-48-like bakteryjnej oporności na karbapenemy
zh-CN	Chinese (China)	细菌碳青霉烯类耐药 blaOXA-23-样基因+blaOXA-48-样基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子病理学 - 基因类分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物基因存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）抗力抗耐性抵抗力抵抗性时刻;随机;随意;瞬间样品样本电阻碳青霉烯类;碳青霉烯类抗生素细菌性细菌的细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaOXA-134-样基因+blaOXA-48-样基因耐性试样阻力

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.