Version 2.78

Term Description

This test detects but does not differentiate between the OXA-23 and OXA-48 groups, which both confer carbapenem resistance. This term was created for, but not limited in use to, the blaOXA antimicrobial resistant marker result in GeneMark's ePlex Blood Culture Identification Gram-Negative Panel.
Source: Regenstrief LOINC

Part Description

LP411469-2   Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
The Ambler classification for carbapenemases utilizes four molecular classes - A, B, C and D. The OXA group of β-lactamases occur mainly in Acinetobacter species and are part of molecular class D. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. PMID: 24696435. Many OXA enzymes (OXA-23-like, OXA-24-like, OXA-48-like, OXA-58-like) are considered to be responsible for the worldwide resistance epidemics. OXA-23-like enzymes have been isolated in carbapenem-resistant Acinetobacter baumannii (CR-AB) in both the US and in China, revealing the importance of national and global efforts to control the spread of CR-AB.
PMID: 24629777 PMID: 26617588 Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
blaOXA-23+48-like genes Islt/Spm Ql
Display Name
Carbapenem resistance blaOXA-24-like+blaOXA-48-like genes Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info
Carbapenem resistance blaOXA-24-like+blaOXA-48-like genes

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
97324-8 Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
85502-3 Carbapenemase resistance genes panel by Molecular genetics method
93407-5 Gram negative blood culture panel by NAA with probe detection in Positive blood culture

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bakterielle Carbapenem-Resistance blaOXA-23-ähnliches+blaOXA-48-ähnliches Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
es-ES Spanish (Spain) Genes de resistencia a los carbapenémicos bacterianos similares a blaOXA-23 + similares a blaOXA-48:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX Spanish (Mexico) Resistencia a los carbapenémicos bacterianos genes similares a blaOXA-23 + genes similares a blaOXA-48:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR French (France) Résistance bactérienne aux carbapénèmases blaOXA-23-like gène+blaOXA-48-like gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, geni blaOXA-23-like+blaOXA-48-like:PrThr:Pt:Isolato/Campione:Ord:Molgen
Synonyms: Genetica molecolare Geni blaOXA-24-like+blaOXA-48-like di resistenza batterica ai carbapenemi Isolato o Campione Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaOXA-23-achtig + blaOXA-48-achtig genen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
Synonyms: blaOXA-134-like isolaat/specimen molgen
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaOXA-23-样基因+blaOXA-48-样基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子病理学 - 基因类 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分离株/标本（样本、样品、试样） 分离物;分离菌;分离菌株;隔离种群 受检物 基因 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗力 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 样品 样本 电阻 碳青霉烯类;碳青霉烯类抗生素 细菌性 细菌的 细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaOXA-134-样基因+blaOXA-48-样基因 耐性 试样 阻力

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93390-3