Version 2.72

93390-3Carbapenem resistance blaOXA-23-like+blaOXA-48-like genes [Presence] in Isolate or Specimen by Molecular methodActive

Term Description

This test detects but does not differentiate between the OXA-23 and OXA-48 groups, which both confer carbapenem resistance. This term was created for, but not limited in use to, the blaOXA antimicrobial resistant marker result in GeneMark's ePlex Blood Culture Identification Gram-Negative Panel.
Source: Regenstrief LOINC

Part Description

LP411469-2   Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes
The Ambler classification for carbapenemases utilizes four molecular classes - A, B, C and D. The OXA group of β-lactamases occur mainly in Acinetobacter species and are part of molecular class D. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. [PMID:24696435]. Many OXA enzymes (OXA-23-like, OXA-24-like, OXA-48-like, OXA-58-like) are considered to be responsible for the worldwide resistance epidemics. OXA-23-like enzymes have been isolated in carbapenem-resistant Acinetobacter baumannii (CR-AB) in both the US and in China, revealing the importance of national and global efforts to control the spread of CR-AB.
[PMID:24629777] [PMID:26617588] Source: Regenstrief LOINC

Fully-Specified Name

Bacterial carbapenem resistance blaOXA-23-like+blaOXA-48-like genes

Additional Names

Short Name
blaOXA-23+48-like genes Islt/Spm Ql
Display Name
Carbapenem resistance blaOXA-24-like+blaOXA-48-like genes Molgen Ql (Islt/Spec)
Consumer Name Alpha
Carbapenem resistance blaOXA-24-like+blaOXA-48-like genes

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.67
Last Updated
Version 2.70
Order vs. Observation

Member of these Panels

LOINC Long Common Name
97324-8 Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
85502-3 Carbapenemase resistance genes panel by Molecular genetics method
93407-5 Gram negative blood culture panel by NAA with probe detection in Positive blood culture

Language Variants Get Info

zh-CNChinese (China)
细菌碳青霉烯类耐药 blaOXA-23-样基因+blaOXA-48-样基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (Netherlands)
bacteriële carbapenemresistentie blaOXA-23-like + blaOXA-48-like genen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
fr-FRFrench (France)
Résistance bactérienne aux carbapénèmases blaOXA-23-like gène+blaOXA-48-like gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)
Resistenza batterica ai carbapenemici, geni blaOXA-23-like+blaOXA-48-like:PrThr:Pt:Isolato/Campione:Ord:Molgen
es-MXSpanish (Mexico)
Resistencia a los carbapenémicos bacterianos genes similares a blaOXA-23 + genes similares a blaOXA-48:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
es-ESSpanish (Spain)
Genes de resistencia a los carbapenémicos bacterianos similares a blaOXA-23 + similares a blaOXA-48:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

LOINC FHIR® API Example - CodeSystem Request Get Info