94303-5
Pregnenolone and 17-Hydroxypregnenolone panel - Serum or Plasma
Active
6765-2 17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma
Part Descriptions
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 [Lab Tests Online:6-17hydroxy/tab/sample]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 17-Hydroxypregnenolone
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 17OH-Preg SerPl-mCnc
- Display Name
- 17-Hydroxypregnenolone [Mass/Vol]
- Consumer Name Alpha Get Info
- 17-Hydroxypregnenolone, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4115
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94303-5 | Pregnenolone and 17-Hydroxypregnenolone panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG41941-2 | 17-Hydroxypregnenolone| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | 17-hidroxipregnenolona: |
| es-ES | Spanish (Spain) | 17-Hidroxipregnenolona: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | 17-hidroxipregnenolona: |
| et-EE | Estonian (Estonia) | 17-hüdroksüpregnenoloon: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | 17-hydroxyprégnénolone: |
| fr-BE | French (Belgium) | 17-hydroxyprégnénolone: |
| fr-FR | French (France) | 17-hydroxyprégnénolone: |
| it-IT | Italian (Italy) | 17-Idrossipregnenolone: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 17-하이드록시프레그네놀론: |
| nl-NL | Dutch (Netherlands) | 17-hydroxypregnenolon: |
| pt-BR | Portuguese (Brazil) | 17-hidroxipregnenolona: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | 17-Гидроксипрегненолон: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | 17-Hidroksipregnenolon: |
| zh-CN | Chinese (China) | 17-羟基孕烯醇酮: Synonyms: 17-Alpha-羟基娠烯醇酮; |
Example Units
| Unit | Source |
|---|---|
| ng/dL | Example UCUM Units |
| ng/dL | REGENSTRIEF |
2837-3 Pregnenolone [Mass/volume] in Serum or Plasma
Part Descriptions
LP15817-7 Pregnenolone
A 21-carbon steroid derived from cholesterol and located in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Source: National Library of Medicine, MeSH 2006
LP15817-7 Pregnenolone
Pregnenolone is a steroid hormone that is increased with hirsutism, adrenal carcinoma, and Cushing's syndrome due to ACTH-secreting pituitary adenoma or ectopic ACTH-secreting tumor. Levels should normally increase following adrenocorticotropic hormone(ACTH) stimulation. Information from Tietz Clinical Guide to Laboratory Tests, 4th edition, AHB Wu, 2006.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Pregnenolone
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Preg SerPl-mCnc
- Display Name
- Pregnenolone [Mass/Vol]
- Consumer Name Alpha Get Info
- Pregnenolone, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2565
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94303-5 | Pregnenolone and 17-Hydroxypregnenolone panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG47715-4 | Pregnenolone| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Πρεγνενολόνη: |
| es-MX | Spanish (Mexico) | Pregnenolona: |
| es-AR | Spanish (Argentina) | pregnenolona: |
| es-ES | Spanish (Spain) | Pregnenolona: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Pregnenoloon: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Pregnénolone: |
| fr-BE | French (Belgium) | Pregnénolone: |
| fr-FR | French (France) | Prégnénolone: |
| it-IT | Italian (Italy) | Pregnenolone: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 프레그네놀론: |
| nl-NL | Dutch (Netherlands) | pregnenolon: |
| pt-BR | Portuguese (Brazil) | Pregnenolona: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Прегненолон: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Pregnenolon: |
| zh-CN | Chinese (China) | 孕烯醇酮: Synonyms: Preg; |
Example Units
| Unit | Source |
|---|---|
| ng/dL | Example UCUM Units |
| ng/dL | REGENSTRIEF |