Version 2.72

94419-9Candida auris [Presence] in Isolate by MS.MALDI-TOFActive

Part Descriptions

LP262556-6   Candida auris
Candida auris is a fungus that was first identified in 2009 in Japan and can cause serious infections in the blood, spinal fluid, and internal organs. This emerging fungus has spread quickly and infections have been documented all over the world. C auris is difficult to identify with the currently available phenotypic methods used by laboratories, and can be misidentified as other species of yeast. It is often resistant to multiple drugs, though resistance can differ broadly across isolates. There are currently no established breakpoints to determine susceptibility, so laboratories have relied on the breakpoints of closely related Candida species or the opinion of experts in mycology. In the United States, C auris is resistant to fluconazole in 90% of infections, to amphotericin B in 30% of infections, and to echinocandins in 5% of infections. Patients at highest risk of infection are those that have been hospitalized for a long time, those with indwelling catheters, and those who have been previously treated with antibiotic or antifungal medication. Symptoms of invasive infection include fever and chills that do not resolve after treatment with antibiotics.[https://www.cdc.gov/fungal/candida-auris/index.html] Source: Regenstrief LOINC

LP186074-3   MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. [PMID:23824373] Source: Regenstrief LOINC, PMID: 23824373

Fully-Specified Name

Candida auris

Additional Names

Short Name
C auris Islt Ql MS.MALDI-TOF
Display Name
C. auris MS.MALDI-TOF Ql (Isol)
Consumer Name Alpha
Candida auris

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
Candida auris:aanwezigheid:moment:isolaat:ordinaal:MALDI-TOF
fr-FRFrench (France)
Candida auris:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Spectrométrie MALDI-TOF
it-ITItalian (Italy)
Candida auris:PrThr:Pt:Isolato:Ord:MS.MALDI-TOF
es-MXSpanish (Mexico)
Candida auris:Presencia o umbral:Punto temporal:Aislado:Ordinal:SRA. MALDI-TOF
es-ESSpanish (Spain)
Candia auris:PrThr:Punto temporal:Aislado:Ord:MS.MALDI-TOF

LOINC FHIR® API Example - CodeSystem Request Get Info