94672-3
24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Mass/volume] in Serum or Plasma
Active
Part Description
LP417252-6 24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol
24,25-dihydroxyvitamin D (24,25 DHD), also known as 24r-Hydroxycalcidiol, is an INactive metabolite produced by alternative hydroxylation of 25 hydroxyvitamin D (25HDN) by the CYP24A1 enzyme. The hydroxylation by CYP24A1 competes with hydroxylation to active form 1,25-dihydroxyvitamin D (1,25 DHD) by the CYP27B1 enzyme, and is an important process that prevents overproduction of 1,25 DHD and resulting vitamin D toxicity. Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene PMID: 22648296.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 24,25(OH)2 VitD SerPl-mCnc
- Display Name
- 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Mass/Vol]
- Consumer Name Alpha Get Info
- 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94674-9 | 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel in Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | 24,25-dihidroxivitamina D3 + 24,25-dihidroxivitamina D2: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 24r-Hydroxycalcidiol + 24r-Hydroxyercalcidiol: |
fr-FR | French (France) | 24r-hydroxycholécalciférol+24r-hydroxyergocalciférol: |
it-IT | Italian (Italy) | 24r-Idrossicalcidiolo+24r-Idrossicalcidiolo: Synonyms: 24,25-Diidrossivitamina D3+24,25-diidrossivitamina D2 Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | 24,25-dihydroxyvitamine D3 + 24,25-dihydroxyvitamine D2: Synonyms: calcidiol; |
zh-CN | Chinese (China) | 24r-羟基钙二醇+24r,25-羟基钙化醇: Synonyms: 24(R),25-二羟基维生素 D; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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