LOINC
Version 2.72

94758-0SARS-related coronavirus E gene [Presence] in Respiratory specimen by NAA with probe detectionActive

Term Description

Qualitative detection of nucleic acids within the envelope (E) gene of SARS-related coronavirus in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Part Description

LP417600-6   SARS-related coronavirus E gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC:coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Fully-Specified Name

Component
SARS-related coronavirus E gene
Property
PrThr
Time
Pt
System
Respiratory
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
SARS-rel CoV E gene Resp Ql NAA+probe
Display Name
SARS-related coronavirus E gene NAA+probe Ql (Resp)
Consumer Name Alpha
SARS-related coronavirus E gene, Respiratory

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Observation

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing
Mapping Guidance LOINC Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.

Member of these Panels

LOINC Long Common Name
96094-8 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory specimen by NAA with probe detection
94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory specimen by NAA with probe detection

Member of these Groups

LG50982-4 SARS-related coronavirus
LG51048-3 SARS-related coronavirus E gene|PrThr|Sys:ANYResp

Language Variants Get Info

zh-CNChinese (China)
SARS 冠状病毒 2 E 基因:存在情况或阈值:时间点:呼吸道:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
SARS-gerelateerd coronavirus E-gen:aanwezigheid:moment:luchtwegen:ordinaal:moleculaire techniek (PCR)
fr-CAFrench (Canada)
gène E du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Respiratoire:Ordinal:Sonde avec amplification de la cible
fr-FRFrench (France)
Coronavirus SARS apparentés ARN gène E:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
de-DEGerman (Germany)
SARS-bezogenes Coronavirus E-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial aus dem Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
it-ITItalian (Italy)
Coronavirus correlato a SARS, gene E:PrThr:Pt:Respiratorio:Ord:Sonda.amp.tar
es-MXSpanish (Mexico)
Gen del coronavirus E relacionado con el SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ESSpanish (Spain)
Gen del coronavirus E relacionado con el SARS:PrThr:Punto temporal:Respiratorio:Ord:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94758-0