Version 2.78

Part Descriptions

LP29176-2   Cyclic citrullinated peptide
Citrullinated peptide (CCP) is a naturally occurring protein that is produced during the metabolism of ornithine to arginine. CCP proteins are found in synovial tissue of patients with rheumatoid arthritis (RA). High levels of antibodies to CCP have a strong association with RA and are predictive of an aggressive and destructive disease outcome. CCP antibody tests can help diagnose RA when the rheumatoid factor (RF) is negative or below 50 IU/mL.(Pagana, Kathleen Deska, and Timothy James Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. St. Louis, MO: Mosby/Elsevier, 2014. Print.) .) IgA to CCP is more elevated in patients with RA than levels found in healthy individuals or those with other rheumatic diseases. PMID: 18565246 Source: Regenstrief LOINC

LP37860-1   Cyclic citrullinated peptide Ab.IgG
Citrulline is a non-standard amino acid that can be incorporated into proteins only by modification of arginine during a variety of biologic processes including inflammation. Several citrullinated proteins have been demonstrated in the RA synovium. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 0.3 to 1% worldwide and leads to progressive joint erosion and disability if not treated early. Identifying citrullinated epitopes targets led to first and then second generation anti-cyclic citrullinated peptide (anti-CCP) antibody assays. These anti-CCP antibodies are important diagnostic and prognostic markers for rheumatoid arthritis (RA) as they: 1) may be more sensitive than RF (rheumatoid factor) in early and established disease, 2) may be a marker of erosive disease, and 3) may be found in healthy patients years prior to clinical onset, and 4) may predict development of undifferentiated arthritis into RA. PMID: 19427413 PMID: 17558653 Source: Regenstrief LOINC, PMID: 19427413

Fully-Specified Name

Component
Cyclic citrullinated peptide Ab.IgG
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Short Name
cCP IgG SerPl IA-aCnc
Display Name
Cyclic citrullinated peptide IgG IA Qn
Consumer Name Alpha Get Info
Cyclic citrullinated peptide IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
95267-1 Connective tissue autoimmune IgG panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG51009-5 Cyclic citrullinated peptide Ab.IgG|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κυκλικό κιτρουλλινιωμένο πεπτίδιο IgG ανοσοσφαιρίνη:Αυθαίρετη συγκέντρωση:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:IA
Synonyms: Ab IgG
es-ES Spanish (Spain) Peptido cíclico citrulinado IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Péptido cíclico citrulinado Ab.IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Tsükliline tsitrulleeritud peptiid antikehad.IgG:Acnc:Pt:S/P:Qn:IA
Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Peptide cyclique citrulliné anticorps IgG:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
fr-CA French (Canada) Peptide citrulliné cyclique, IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-BE French (Belgium) Peptide citrulliné cyclique Anticorps. IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
Synonyms: Anticorps CCP
it-IT Italian (Italy) Peptide ciclico citrullinato Ab.IgG:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: anticorpi IgG anticorpo CCP Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) cyclisch citrulline-peptide As.IgG:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
ru-RU Russian (Russian Federation) Циклический цитруллинизированный пептид Ат.IgG:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA
Synonyms: Антитело Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Siklik sitrülline peptid Ab.IgG:SçKons:Zmlı:Ser/Plaz:Kant:İA
Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay
zh-CN Chinese (China) 环瓜氨酸肽 抗体.IgG:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 cCP;CCP3;环瓜氨酸肽;Cyclic Citrullinated Peptide 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗环瓜氨酸肽 抗环瓜氨酸肽抗体 时刻;随机;随意;瞬间 环瓜氨酸肽 Ab 环瓜氨酸肽 Ab.IgG 环瓜氨酸肽 IgG 缩氨酸 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94874-5