95122-8
Coagulation factor VIII inhibitor [Interpretation] in Platelet poor plasma by Chromogenic method
Active
Part Descriptions
LP29023-6 Coagulation factor VIII inhibitor
Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites PMID: 23610614.
Source: Regenstrief LOINC
LP14587-7 Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Coagulation factor VIII inhibitor
- Property
- Imp
- Time
- Pt
- System
- PPP
- Scale
- Nom
- Method
- Chromo
Additional Names
- Short Name
- Fact VIII Inhib PPP Chro-Imp
- Display Name
- Coagulation factor VIII inhibitor Chromogenic method (PPP) [Interp]
- Consumer Name Alpha Get Info
- Coagulation Factor VIII Inhibitor, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
95121-0 | Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Chromogenic method |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Factor de coagulación VIII inhibido: |
es-MX | Spanish (Mexico) | Inhibidor del factor VIII de la coagulación: |
fr-CA | French (Canada) | Inhibiteur du facteur VIII: |
fr-FR | French (France) | Facteur VIII inhibiteur: |
fr-BE | French (Belgium) | Inhibiteur du facteur VIII: Synonyms: F VIII |
it-IT | Italian (Italy) | Fattore di coagulazione VIII, inibitore: Synonyms: Cromogenico (Enzima) Impressione/interpretazione di studio Inibitore del fattore di coagulazione VIII Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione |
nl-NL | Dutch (Netherlands) | stollingsfactor VIII remmer: Synonyms: coagulatiemethode |
ru-RU | Russian (Russian Federation) | Коагуляции фактор VIII ингибитор: Synonyms: Впечатление/интерпретация исследования Номинальный; |
tr-TR | Turkish (Turkey) | Koagülasyon faktörü VIII inhibitörü: |
zh-CN | Chinese (China) | 凝血因子 VIII 抑制剂: Synonyms: AHF; |
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