95578-1

Tetrahydrodeoxycortisol [Z-score] in 24 hour Urine

Active

Part Description

LP15884-7 Tetrahydrodeoxycortisol
Tetrahydrodeoxycortisol (THS) is a mineralocorticoid the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approximately 5% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4%) and the T-allele of the -344 C/T polymorphism of CYP11B2 is more strongly associated with higher THS levels than the C-allele. PMID: 16984984, PMID: 15522937, PMID: 15272911. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Tetrahydrodeoxycortisol

LOINC Names Get Info

Fully-Specified Name: Tetrahydrodeoxycortisol:Zscore:24H:Urine:Qn:
Long Common Name: Tetrahydrodeoxycortisol [Z-score] in 24 hour Urine
Short Name: TH-DC 24h Z-score Ur
Display Name: Tetrahydrodeoxycortisol (24H U) [Z-score]
Consumer Name Alpha Get Info: Tetrahydrodeoxycortisol, Urine

Part Model Get Info

Component
Tetrahydrodeoxycortisol
LP15884-7
- Analyte
  Tetrahydrodeoxycortisol
  LP15884-7
  - Component Numerator
    Tetrahydrodeoxycortisol
    LP15884-7
    - Component Numerator Core
      Tetrahydrodeoxycortisol
      LP15884-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Zscore
LP164005-3
Time
24H
LP6924-7
- Time Core
  24H
  LP6924-7
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.69 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
95556-7	Adrenal cancer risk assessment and urine steroid fractions panel

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Tetrahydrodeoxykortizol:Z-skóre:24 hodin:Moč:Kvantitativní:
el-GR	Greek (Greece)	Τετραϋδροδεοξυκορτιζόλη:Zscore:24H:Ούρα:Qn: Synonyms: 24H CHEM Qn Zscore Ούρα Τετραϋδροδεοξυκορτιζόλη
es-ES	Spanish (Spain)	Tetrahidrodesoxicortisol:Puntuación Z:24 horas:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Tetrahidrodesoxicortisol:Puntuación Z:24H:Orina:Cuantitativo:
fr-FR	French (France)	Tétrahydro-11-déoxycortisol:Z score:24H:Urine:Numérique:
it-IT	Italian (Italy)	Tetraidrodeossicortisolo:Zscore:24h:Urine:Qn: Synonyms: 24 Ore Chimica Z-score
nl-NL	Dutch (Netherlands)	tetrahydrodeoxycortisol:Z-score:24 uur:urine:kwantitatief: Synonyms: 24U
pl-PL	Polish (Poland)	Tetrahydrodeoksykortyzol:standardowa wartość Z:24h:mocz:ilościowy: Synonyms: 24 godziny
ru-RU	Russian (Russian Federation)	Тетрагидродеоксикортизол:Z-тест:24 часа:Моча:Колич: Synonyms: Z-тест Фишера Количественный Тетрагидродезоксикортизол
tr-TR	Turkish (Turkey)	Tetrahidrodeoksikortizol:Zskoru:24Sa:İdrar:Kant:
zh-CN	Chinese (China)	四氢脱氧皮质醇:Z评分:24小时:尿液:定量型: Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 TH-DC;四氢-11-脱氧皮质醇;四氢脱氧皮质甾醇;四氢脱氧皮醇 Z分;Z分值;Z分数;Z得分;Z-评分;Z评分（分值、得分、分数）化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉

Example Units

Unit	Source
{Zscore}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.