Version 2.77

Part Description

LP207328-8   Bedaquiline
Bedaquiline (trade name Sirturo) is a diarylquinoline anti-tuberculosis drug. When it was approved by the U.S. FDA in 2012, it was the first time in 40 years that a drug with a different mechanism of action compared to the existing TB treatments had been approved, and it is specifically approved to treat adults with pulmonary multi-drug resistant tuberculosis (MDR TB) and extensively drug resistant tuberculosis (XDR TB). Badaquiline should only be used when an effective treatment regimen cannot otherwise be provided. The most common side effects of bedaquiline in studies were nausea, joint and chest pain, and headache, however the drug also has a black-box warning for life-threatening arrhythmias, as it may induce long QT syndrome by blocking the hERG channel. PMID: 23776831 Source: Regenstrief LOINC

Fully-Specified Name

Component
Bedaquiline
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Bedaquiline Islt Genotyp
Display Name
Bedaquiline Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Bedaquiline

Example Answer List: LL3666-6

Source: North Carolina State Laboratory of Public Health
Answer Code Score Answer ID
Resistant LA6676-6
Susceptible LA24225-7

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
89486-5 Mycobacterial susceptibility panel Qualitative by Genotype method
94053-6 Mycobacterium tuberculosis complex resistance panel by Molecular genetics method

Member of these Groups Get Info

LOINC Group Group Name
LG41784-6 BedaquilineSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bedaquilin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal:Genotypisierung
es-ES Spanish (Spain) Bedaquilina:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Bedaquilina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Bédaquiline:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Bedaquilina:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) bedaquiline:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 贝达喹啉:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 6-溴-ALPHA-[2-(二甲基氨基)乙基]-2-甲氧基-ALPHA-1-萘基-BETA-苯基-3-喹啉乙醇;CAS 843663-66-1 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96107-8