96418-9

Cells.CD3-CD14-CD45+CD56+DOCK8+/100 Cells.CD3-CD14-CD45+CD56+ in Blood by Flow cytometry (FC)

Active

Term Description

This term represents the percentage of NK cells (Cells.CD3-CD14-CD45+CD56+) that express the DOCK8 protein.
Source: Regenstrief LOINC

Part Descriptions

LP420089-7 Cells.CD3-CD14-CD45+CD56+DOCK8+
Dedicator of cytokinesis 8 (DOCK8) protein plays a role in regulating the cellular cytoskeleton, particularly microfilaments. DOCK8 is important in immunity by contributing to cellular migration, cytotoxicity, antibody production, and immunological memory. Deficiency of DOCK8 causes an immunodeficiency that presents in childhood with features including recurrent sinopulmonary infections, cutaneous viral infection, Staphylococcus aureus skin infections, cancer, and atopic disease (due to hyperimmunoglobulin E). NK cells (CD45+CD14-CD3-CD56+), T cells (CD3+CD14-CD45+), B cells (CD3-CD14-CD19+CD45+), and monocytes (CD45+CD14+) are all expected to express the DOCK8 protein. Therefore, assessment of DOCK8 expression on immune cells facilitates the diagnosis of DOCK8 deficiency. PMID: 28625885 Source: Regenstrief LOINC

LP17733-4 CD14
Found on Monocytes
Associated with some AML Source: Regenstrief LOINC

Fully-Specified Name

Component: Cells.CD3-CD14-CD45+CD56+DOCK8+/100 Cells.CD3-CD14-CD45+CD56+
Property: NFr
Time: Pt
System: Bld
Scale: Qn
Method: Flow cytometry

Additional Names

Short Name: NK Cells DOCK8+/NK Cells NFr Bld FC
Display Name: Cells.CD3-CD14-CD45+CD56+DOCK8+/100 Cells.CD3-CD14-CD45+CD56+ FC (Bld)
Consumer Name Alpha Get Info: Cells.CD3-CD14-CD45+CD56+DOCK8+ 100 Cells.CD3-CD14-CD45+CD56+, Blood

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.69
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96415-5	DOCK8 expression panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Células CD3-CD14-CD45+CD56+DOCK8+/100 células CD3-CD14-CD45+CD56+:Fracción numérica:Punto temporal:Sangre:Qn:Citometria de flujo (FC) Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cells.CD3-CD14-CD45 + CD56 + DOCK8 + / 100 Cells.CD3-CD14-CD45 + CD56 +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Citometría de flujo (FC)
fr-FR	French (France)	CD3-CD14-CD45+CD56+DOCK8+/100 cellules CD3-CD14-CD45+CD56+:Fraction de nombres:Ponctuel:Sang:Numérique:Cytométrie de flux
it-IT	Italian (Italy)	Cellule.CD3-CD14-CD45+CD56+DOCK8+/100 cellule.CD3-CD14-CD45+CD56+:NFr:Pt:Sangue:Qn:Citometria a flusso Synonyms: Cellule CD3 Citometria a flusso (FC) Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NL	Dutch (Netherlands)	cellen.CD3-CD14-CD45+CD56+DOCK8+/100 cellen.CD3-CD14-CD45+CD56+:getalsfractie:moment:bloed:kwantitatief:flowcytometrie
zh-CN	Chinese (China)	细胞.CD3-CD14-CD45+CD56+DOCK8+/100 个细胞.CD3-CD14-CD45+CD56+:计数型分数:时间点:全血:定量型:流式细胞测量术 Synonyms: B220;CD45R;CD45RA;CD45RB;CD45RC;CD45RO;LCA;Ly5;T200;白细胞共同 Ag;白细胞共同分化 Ag;白细胞共同分化抗原;白细胞共同抗原 CD3细胞 Leu19;Leu-19;NCAM;NKH1;神经细胞粘附分子;神经细胞粘附分子（Neural cell adhesion molecule，NCAM）;神经细胞黏附分子 Leu4;Leu-4;T3 LeuM3 Leu-M3 LPS-R Mo2 Mo-2 My4 My-4 动态发现于单核细胞之上，与某些急性髓系白血病（AML）相关。可用数量表示的;定量性;数值型;数量型;连续数值型标尺数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间流流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计细胞含量;细胞性;细胞性质;细胞构成;细胞类细胞标志物脂多糖受体（LPS receptor，LPS-R）血;血液

Example Units

Unit	Source
%	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96418-9

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.