Version 2.73

96516-0Toscana virus IgG Ab [Presence] in Specimen by ImmunoassayActive

Term Description

Source: Regenstrief LOINC

Part Descriptions

LP190786-6   Toscana virus
Toscana virus (TOSV) was identified in 1971 in central Italy from sandflies Phlebotomus perniciosus and Phlebotomus perfiliewi [PMID:24175218]. TOSV belongs to the family Phenuiviridae, genus Phlebovirus [NCBI Taxonomy:11590)]. TOSV is a serotype of the species Sandfly fever Naples virus [PMID:24175218]. TOSV is the only neurotropic sandfly phlebovirus typically causing meningitis and encephalitis. Additional neuroinvasive manifestations such as Guillain-Barré syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness, and facial paralysis, have been reported. Toscana virus broadly circulates in in European Mediterranean basin and Northern Africa [PMID:32878929]. Source: Regenstrief LOINC

LP190784-1   Toscana virus Ab.IgG
The Toscana virus (TOSV) belongs to the Phlebovirus genus of the Bunyaviridae family, and is an arthropod-borne virus transmitted to humans by Phlebotomus spp sandflies. The Toscana virus infection is characterized by fever, strong headache, and meningitis, or meningoencephalitis. TOSV is the major cause of aseptic meningitis (95%) and meningoencephalitis (4.5%) and influenza-like illness during the summer season. Some unusual clinical manifestations due to TOSV with severe sequelae, such as ischemic complications and hydrocephalus, have been reported. TOSV represents an important emerging pathogen and it is being investigated in several countries on the Mediterranean basin, including Italy, France, Spain, Portugal and Cyprus. Phylogenetic analysis has distinguished two genotypes of TOSV, A and B. The first is circulating mainly in Italy and the second in Spain, indicating a different geographic distribution possibly related to the vector. There is no treatment for TOSV infection except for supportive therapy.[PMID:20517492] Source: Regenstrief LOINC, PMID: 20517492

LP190786-6   Toscana virus
The Toscana virus (TOSV) belongs to the Bunyaviridae family whose genome is made of three negative single-stranded RNA segments. There are two genotypes of TOSV: A, found mainly in Italy, and B, occurring mainly in Spain. The distribution of the two genotypes may indicate the involvement of different vectors. Infection by TOSV is most prevalent in Italy and Spain in the summer months, though the geographical region where TOSV is expanding includes other countries in the Mediterranean basin. TOSV is transmitted to humans by the Phlebotomus species of sandflies. Though the animal reservoir has not been identified, TOSV has been isolated from the brain of a bat, which raises the question of it possibly being a host to the virus. TOSV causes aseptic meningitis in 95% of the people it infects, meningoencephalitis in 4.5% of those infected, and an influenza-like illness in the remaining .5% who are infected. Recently, unusual symptoms associated with TOSV have included ischemic complications and hydrocephalus. TOSV is emerging as an important pathogen as its distribution increases due to changes in the climate, globalization and habitat modification. Other than supportive therapy, there is no treatment for infection with TOSV.[PMID:20517492] Source: Regenstrief LOINC

Fully-Specified Name

Toscana virus Ab.IgG

Additional Names

Short Name
Display Name
Toscana virus IgG IA Ql (Specimen)
Consumer Name Alpha
Toscana virus IgG antibody, Specimen

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
托斯卡纳病毒 抗体.IgG:存在情况或阈值:时间点:XXX:序数型:免疫测定法
nl-NLDutch (Netherlands)
Toscana virus As.IgG:aanwezigheid:moment:XXX:ordinaal:immunoassay
fr-FRFrench (France)
Toscana virus Ac IgG:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Immunoanalyse
de-DEGerman (Germany)
Toskana-Virus Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Immunoassay
it-ITItalian (Italy)
Virus Toscana Ab.IgG:PrThr:Pt:XXX:Ord:IA
es-MXSpanish (Mexico)
Toscana virus Ab.IgG:Presencia o umbral:Punto temporal:XXX:Ordinal:Inmunoensayo
es-ESSpanish (Spain)
Virus Toscana IgG:PrThr:Punto temporal:XXX:Ord:IA
tr-TRTurkish (Turkey)
Toscana virüs Ab.IgG:MevcEşik:Zmlı:XXX:Srl:İA

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