LOINC
Version 2.70

97959-1Silver Birch recombinant (rBet v) 1 IgG4 Ab [Mass/volume] in SerumActive

Part Descriptions

LP28707-5   Betula verrucosa recombinant (rBet v) 1
Bet v 1 from a family of proteins related to plant defense is related to similar compounds from many fruits (apple, cherry apricot etc.) as well as celery and carrots. In patients with birch allergies this antigen may the root cause of allergies from many foods. Recombinant Bet V 1 (rBet V1) is used for birch allergy testing and is being used in trials of desensitization. Source: Regenstrief Institute

LP28707-5   Betula verrucosa recombinant (rBet v) 1
Recombinant non-glycosylated protein produced in an E. coli strain carrying a cloned cDNA encoding Betula verrucosa allergen Bet v 1

The major allergen of birch tree pollen is Bet v 1. Recombinant Bet v 1 was among the first allergen-encoding cDNAs isolated and has significant sequence homology to a group of pathogenesis-related plant proteins and has been classified as a PR-10 protein. Copyright Copyright © 2006 Phadia AB. Source: ImmunoCap, ImmunoCap

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a “blocking” antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID: 26023323] . IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Betula verrucosa recombinant (rBet v) 1 Ab.IgG4
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Silver Birch (rBet v) 1 IgG4-mCnc
Display Name
Silver Birch recombinant (rBet v) 1 IgG4 (S) [Mass/Vol]
Consumer Name Alpha
Silver birch recombinant (rBet v) 1 IgG4 antibody

Basic Attributes

Class
ALLERGY
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
白桦树 重组 (rBet v) 1 抗体.IgG4:质量浓度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
Betula verrucosa recombinant (rBet v) 1 As.IgG4:massa/volume:moment:serum:kwantitatief:
fr-BEFrench (Belgium)
Allergène recombinant rBet v 1 de Betula verrucosa Anticorps. IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-CAFrench (Canada)
Allergène recombinant (rBet v) 1 de Betula verrucosa , IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
it-ITItalian (Italy)
Betula verrucosa, ricombinante rBet v1 , Ab.IgG4:MCnc:Pt:Siero:Qn:
ru-RURussian (Russian Federation)
Betula verrucosa рекомбинантный (rBet v) 1 Ат.IgG4:МассКонц:ТчкВрм:Сыв:Колич:
es-ESSpanish (Spain)
Abedul de plata (Betula verrucosa) rBet v1 IgG4:Concentración de masa:Punto temporal:Suero:Qn:
tr-TRTurkish (Turkey)
Betula verrucosa rekombinant (rBet v) 1 Ab.IgG4:KütlKons:Zmlı:Ser:Kant:

Example Units

Unit Source
mg/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97959-1