LOINC
Version 2.70

97980-7Hazelnut recombinant (rCor a) 14 IgG4 Ab [Mass/volume] in SerumActive

Part Descriptions

LP212203-6   Corylus avellana recombinant (rCor a) 14
Corylus avellana (Cor a) 14 is a seed storage protein of hazelnut that measures 13-14 kDa and is a 2S albumin. 2S albumins have a very stable intrinsic structure that is preserved even in harsh environments, such as the gastrointestinal tract where it is believed to initiate an immune response. [PMID: 18949071] The Cor a 14 protein affects 70% of children and 39% of adults sensitive to hazelnut proteins and is associated with severe allergic reactions in both demographic groups.(http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/food-of-plant-origin/allergen-components/rcor-a-14-hazelnut/) Cor a 14 sensitivity is predicitive of a severe allergic reaction when exposure to Cor a 14 occurs. [PMID: 23582909] Source: Regenstrief LOINC

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a “blocking” antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID: 26023323] . IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Corylus avellana recombinant (rCor a) 14 Ab.IgG4
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Hazelnut (rCor a) 14 IgG4-mCnc
Display Name
Hazelnut recombinant (rCor a) 14 IgG4 (S) [Mass/Vol]
Consumer Name Alpha
Hazelnut recombinant (rCor a) 14 IgG4 antibody

Basic Attributes

Class
ALLERGY
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
榛子 重组 (rCor a) 14 抗体.IgG4:质量浓度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
Corylus avellana (rCor a) recombinant 14 As.IgG4:massa/volume:moment:serum:kwantitatief:
it-ITItalian (Italy)
Corylus avellana ricombinante (rCor a) 14 , Ab.IgG4:MCnc:Pt:Siero:Qn:
es-ESSpanish (Spain)
Recombinante (rCor a) Corylus avellana IgG4:Concentración de masa:Punto temporal:Suero:Qn:

Example Units

Unit Source
mg/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97980-7