Version 2.70

97980-7Hazelnut recombinant (rCor a) 14 IgG4 Ab [Mass/volume] in SerumActive

Part Descriptions

LP212203-6   Corylus avellana recombinant (rCor a) 14
Corylus avellana (Cor a) 14 is a seed storage protein of hazelnut that measures 13-14 kDa and is a 2S albumin. 2S albumins have a very stable intrinsic structure that is preserved even in harsh environments, such as the gastrointestinal tract where it is believed to initiate an immune response. [PMID: 18949071] The Cor a 14 protein affects 70% of children and 39% of adults sensitive to hazelnut proteins and is associated with severe allergic reactions in both demographic groups.(http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/food-of-plant-origin/allergen-components/rcor-a-14-hazelnut/) Cor a 14 sensitivity is predicitive of a severe allergic reaction when exposure to Cor a 14 occurs. [PMID: 23582909] Source: Regenstrief LOINC

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a “blocking” antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID: 26023323] . IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Corylus avellana recombinant (rCor a) 14 Ab.IgG4

Additional Names

Short Name
Hazelnut (rCor a) 14 IgG4-mCnc
Display Name
Hazelnut recombinant (rCor a) 14 IgG4 (S) [Mass/Vol]
Consumer Name Alpha
Hazelnut recombinant (rCor a) 14 IgG4 antibody

Basic Attributes

First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
榛子 重组 (rCor a) 14 抗体.IgG4:质量浓度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
Corylus avellana (rCor a) recombinant 14 As.IgG4:massa/volume:moment:serum:kwantitatief:
it-ITItalian (Italy)
Corylus avellana ricombinante (rCor a) 14 , Ab.IgG4:MCnc:Pt:Siero:Qn:
es-ESSpanish (Spain)
Recombinante (rCor a) Corylus avellana IgG4:Concentración de masa:Punto temporal:Suero:Qn:

Example Units

Unit Source
mg/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info