Version 2.70

97987-2Honey bee recombinant (rApi m) 10 IgG4 Ab [Mass/volume] in SerumActive

Part Descriptions

LP220397-6   Apis mellifera recombinant (rApi m) 10
Apis mellifera (Honey Bee) was native to Africa, Europe and the Middle East but is now found worldwide. Sensitivity to honey bee venom is estimated to be 15-25% of the population and higher for people living in rural areas.(http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/venoms/allergens/honey-bee/) Since exposure to honey bee venom can be life threatening to sensitized individuals determining the various allergens in honey bee venom can add immunotherapeutic treatment options. Fifty percent of individuals allergic to honey bee venom have been found to react to Api m 10 (also known as Icarapin variant 2, carbohydrate-rich protein). Testing for Api m 10 could be important in accurately diagnosing and treating a significant portion of the population allergic to honey bee venom. [PMID: 21658068] Source: Regenstrief LOINC

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a “blocking” antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID: 26023323] . IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Apis mellifera recombinant (rApi m) 10 Ab.IgG4

Additional Names

Short Name
Honey bee (rApi m) 10 IgG4-mCnc
Display Name
Honey bee recombinant (rApi m) 10 IgG4 (S) [Mass/Vol]
Consumer Name Alpha
Honey bee recombinant (rApi m) 10 IgG4 antibody

Basic Attributes

First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
意大利蜜蜂 重组 (rApi m) 10 抗体.IgG4:质量浓度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
Apis mellifera (honingbij) recombinant (rApi m) 10 As.IgG4:massa/volume:moment:serum:kwantitatief:
it-ITItalian (Italy)
Apis mellifera, ricombinante (rApi m) 10 , Ab.IgG4:MCnc:Pt:Siero:Qn:
es-ESSpanish (Spain)
Recombinate rApi m 10. Honey bee (Apis mellifera) IgG4:Concentración de masa:Punto temporal:Suero:Qn:

Example Units

Unit Source
mg/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info