104537-6
Creatine, guanidinoacetate and creatinine panel - Serum or Plasma
Active
33244-5 Guanidinoacetate [Moles/volume] in Serum or Plasma
Term Description
Used to assess abnormalities in the synthesis of creatine.
Source: Regenstrief LOINC
Part Descriptions
LP30825-1 Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Guanidinoacetate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Guanidinoacetate SerPl-sCnc
- Display Name
- Guanidinoacetate [Moles/Vol]
- Consumer Name Alpha Get Info
- Guanidinoacetate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.73
- Change Reason
- Changed Plas to Ser/Plas based on documentation that ARUP can use either serum or plasma.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 12429
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79289-5 | Creatine and guanidinoacetate panel - Serum or Plasma |
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Guanidinoacetat: |
| es-MX | Spanish (Mexico) | Guanidinoacetato: |
| es-AR | Spanish (Argentina) | guanidinoacetato: |
| es-ES | Spanish (Spain) | Guanidinoacetato: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Guanidinoatsetaat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Guanidinoacétate: |
| fr-FR | French (France) | Guanidinoacétate: |
| fr-CA | French (Canada) | Guanidinoacétate: |
| it-IT | Italian (Italy) | Guanidinoacetato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | Guanidinoacetate: |
| nl-NL | Dutch (Netherlands) | guanidinoacetaat: |
| pt-BR | Portuguese (Brazil) | Guanidinoacetato: Synonyms: glycocyamine; |
| ru-RU | Russian (Russian Federation) | Гуанидинацетат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Guanidinoasetat: |
| zh-CN | Chinese (China) | 胍基乙酸: Synonyms: GAA; |
Example Units
| Unit | Source |
|---|---|
| mmol/mL | Example UCUM Units |
14682-9 Creatinine [Moles/volume] in Serum or Plasma
Part Descriptions
LP14355-9 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Creatinine |
Fully-Specified Name
- Component
- Creatinine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Creat SerPl-sCnc
- Display Name
- Creatinine [Moles/Vol]
- Consumer Name Alpha Get Info
- Creatinine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2641
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 75868-0 | HEDIS 2015 Value Sets |
| 79544-3 | HEDIS 2016 Value Sets |
| 82955-6 | HEDIS 2017 Value Sets |
| 87625-0 | HEDIS 2018 Value Sets |
| 90766-7 | HEDIS 2019 Value Sets |
| 96789-3 | Sequential Organ Failure Assessment SOFA |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG50024-5 | Creatinine| |
| LG2923-3 | Creatinine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Creatinin: |
| el-GR | Greek (Greece) | Κρεατινίνη: |
| es-AR | Spanish (Argentina) | creatinina: |
| es-ES | Spanish (Spain) | Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Creatinina: |
| et-EE | Estonian (Estonia) | Kreatiniin: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Créatinine: |
| fr-FR | French (France) | Créatinine: |
| fr-CA | French (Canada) | Créatinine: |
| it-IT | Italian (Italy) | Creatinina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 크레아티닌: |
| nl-NL | Dutch (Netherlands) | creatinine: Synonyms: kreatinine |
| pl-PL | Polish (Poland) | Kreatynina: |
| pt-BR | Portuguese (Brazil) | Creatinina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Креатинин: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Kreatinin: |
| uk-UA | Ukrainian (Ukraine) | Креатинін: Synonyms: Chemistry; |
| zh-CN | Chinese (China) | 肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
| umol/L | eCHN |
15045-8 Creatine [Moles/volume] in Serum or Plasma
Part Descriptions
LP15509-0 Creatine
Creatine is a nitrogenous organic acid that naturally occurs in vertebrates and helps to supply energy to muscle cells. In solution, creatine is in equilibrium with creatinine.
Creatine is naturally produced in the human body from amino acids primarily in the kidney and liver. It is transported in the blood for use by muscles. Approximately 95% of the human body's total creatine is located in skeletal muscle. Genetic deficiencies in the creatine biosynthetic pathway lead to various severe neurological defects.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Creatine (Wikipedia)
Fully-Specified Name
- Component
- Creatine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Creatine SerPl-sCnc
- Display Name
- Creatine [Moles/Vol]
- Consumer Name Alpha Get Info
- Creatine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7627
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79289-5 | Creatine and guanidinoacetate panel - Serum or Plasma |
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG45731-3 | Creatine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Creatin: |
| es-MX | Spanish (Mexico) | Creatina: |
| es-AR | Spanish (Argentina) | creatina: |
| es-ES | Spanish (Spain) | Creatina: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Kreatiin: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Créatine: |
| fr-FR | French (France) | Créatine: |
| fr-CA | French (Canada) | Créatine: |
| it-IT | Italian (Italy) | Creatina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 크레아틴: |
| nl-NL | Dutch (Netherlands) | creatine: |
| pl-PL | Polish (Poland) | Kreatynina: |
| pt-BR | Portuguese (Brazil) | Creatina: Synonyms: Substance concentration; |
| ru-RU | Russian (Russian Federation) | Креатинин: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Kreatin: |
| uk-UA | Ukrainian (Ukraine) | Креатин: Synonyms: Chemistry; |
| zh-CN | Chinese (China) | 肌酸: Synonyms: Cr; |
Example Units
| Unit | Source |
|---|---|
| mmol/L | Example UCUM Units |
| mmol/L | eCHN |
104540-0 Guanidinoacetate/Creatinine [Molar ratio] in Serum or Plasma
Part Descriptions
LP30825-1 Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Guanidinoacetate/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Guanidinoacetate/Creat SerPl-sRto
- Display Name
- Guanidinoacetate/Creatinine [Molar ratio]
- Consumer Name Alpha Get Info
- Guanidinoacetate/Creatinine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Guanidinoacetato/Creatinina: Synonyms: Cuantitativo |
| fr-CA | French (Canada) | Guanidinoacétate/Créatinine: |
| fr-BE | French (Belgium) | Guanidinoacétate/Créatinine: |
| it-IT | Italian (Italy) | Guanidinoacetato/Creatinina: Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di sostanza Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | guanidinoacetaat/creatinine: Synonyms: kreatinine |
| ru-RU | Russian (Russian Federation) | Гуанидинацетат/Креатинин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | Guanidinoasetat/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 胍基乙酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| umol/mmol{creat} | Example UCUM Units |
105124-2 Guanidinoacetate/Creatine [Molar ratio] in Serum or Plasma
Part Descriptions
LP30825-1 Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378
Source: Regenstrief LOINC
LP32032-2 Creatine
An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Guanidinoacetate/Creatine
- Property
- SRto
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Guanidinoacetate/Creatine SerPl-sRto
- Display Name
- Guanidinoacetate/Creatine [Molar ratio]
- Consumer Name Alpha Get Info
- Guanidinoacetate/Creatine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Guanidinoacetato/Creatina: Synonyms: Cuantitativo |
| it-IT | Italian (Italy) | Guanidinoacetato/Creatina: Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di sostanza Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | guanidinoacetaat/creatine: |
| ru-RU | Russian (Russian Federation) | Гуанидинацетат/Креатин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | Guanidinoasetat/Kreatin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 胍基乙酸/肌酸: Synonyms: Cr; |
Example Units
| Unit | Source |
|---|---|
| umol/mmol | Example UCUM Units |
104539-2 Creatine/Creatinine [Molar ratio] in Serum or Plasma
Part Descriptions
LP15509-0 Creatine
Creatine is a nitrogenous organic acid that naturally occurs in vertebrates and helps to supply energy to muscle cells. In solution, creatine is in equilibrium with creatinine.
Creatine is naturally produced in the human body from amino acids primarily in the kidney and liver. It is transported in the blood for use by muscles. Approximately 95% of the human body's total creatine is located in skeletal muscle. Genetic deficiencies in the creatine biosynthetic pathway lead to various severe neurological defects.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Creatine (Wikipedia)
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Creatine/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Creatine/Creat SerPl-sRto
- Display Name
- Creatine/Creatinine [Molar ratio]
- Consumer Name Alpha Get Info
- Creatine/Creatinine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Creatina/Creatinina: Synonyms: Cuantitativo |
| fr-BE | French (Belgium) | Créatine/Créatinine: |
| fr-CA | French (Canada) | Créatine/Créatinine: |
| it-IT | Italian (Italy) | Creatina/Creatinina: Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di sostanza Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | creatine/creatinine: Synonyms: kreatinine |
| pl-PL | Polish (Poland) | Kreatynina/kreatynina: |
| ru-RU | Russian (Russian Federation) | Креатинин/Креатинин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | Kreatin/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 肌酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mmol/mol{creat} | Example UCUM Units |
104538-4 Creatine, guanidinoacetate and creatinine pattern [Interpretation] in Serum or Plasma Narrative
Fully-Specified Name
- Component
- Creatine, guanidinoacetate & creatinine pattern
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Additional Names
- Short Name
- Cr, GAA and Creat pattern SerPl-Imp
- Display Name
- Creatine, guanidinoacetate and creatinine pattern Nar [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Creatine, guanidinoacetate and Creatinine pattern test result, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Patrón de creatina, guanidinoacetato y creatinina: |
| it-IT | Italian (Italy) | Creatina, guanidinoacetato & creatinina, profilo: Synonyms: Chimica Impressione/interpretazione di studio Plasma Profilo creatina, guanidinoacetato e creatinina Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | creatine, guanidinoacetaat & creatinine pattern: Synonyms: kreatinine |
| tr-TR | Turkish (Turkey) | Kreatin, guanidinoasetat ve kreatinin örüntüsü: Synonyms: Kreatin, guanidinoasetat ve kreatinin apterni |
| zh-CN | Chinese (China) | 肌酸、 Synonyms: CR; |