46437-0
Rheumatoid Factor and Cyclic Citrullinated Peptide IgG panel [Units/volume] - Serum
Active
11572-5 Rheumatoid factor [Units/volume] in Serum or Plasma
Part Descriptions
LP16738-4 Rheumatoid factor
Rheumatoid factor (RF or RhF) is a blood test performed in patients with suspected rheumatoid arthritis (RA). It is an auto-antibody directed against the Fc portion of IgG, which is itself an antibody. RF and IgG form immune complexes, which are part of the disease process (serum sickness) of various rheumatological diseases. Storage/Transport Temperature: 1 mL plasma or serum, 2-8°C. (Min: 0.2 mL) Submit specimen in an ARUP Amber Transport Tube. Rheumatoid factor can also be a cryoglobulin (antibody that precipitates on cooling of a blood sample); it can be either type 2 (monoclonal IgM to polyclonal IgG) or 3 (polyclonal IgM to polyclonal IgG) cryoglobulin.
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Source: Wikipedia, Rheumatoid factor (Wikipedia)
LP16738-4 Rheumatoid factor
Antibodies found in adult rheumatoid arthritis patients that are directed against gamma-chain immunoglobulins.
Source: National Library of Medicine, MeSH 2006
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Rheumatoid factor
- Property
- ACnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Rheumatoid fact SerPl-aCnc
- Display Name
- Rheumatoid factor Qn
- Consumer Name Alpha Get Info
- Rheumatoid factor, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0j-a
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 497
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 46437-0 | Rheumatoid Factor and Cyclic Citrullinated Peptide IgG panel [Units/volume] - Serum |
| 103139-2 | Systemic lupus Ab panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG357-0 | Rheumatoid factor| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Rheumafaktor: |
| de-AT | German (Austria) | Synonyms: Rheumafaktor |
| el-GR | Greek (Greece) | Ρευματοειδής παράγοντας: Synonyms: RF |
| es-MX | Spanish (Mexico) | Factor reumatoide: |
| es-ES | Spanish (Spain) | Factor Reumatoide: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | factor reumatoideo: |
| et-EE | Estonian (Estonia) | Reumatoidfaktor: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Facteur rhumatoïde: |
| fr-BE | French (Belgium) | Facteur rhumatoïde: Synonyms: RF |
| fr-FR | French (France) | Facteurs rhumatoïdes: |
| it-IT | Italian (Italy) | Fattore reumatoide: Synonyms: Concentrazione Arbitraria FR Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| ko-KR | Korean (Korea, Republic Of) | 류마티스 인자: |
| nl-NL | Dutch (Netherlands) | reumafactor: |
| pl-PL | Polish (Poland) | Czynnik reumatoidalny: |
| pt-BR | Portuguese (Brazil) | Fator reumatóide: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Ревматоидный фактор: Synonyms: Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Romatoid faktör: |
| uk-UA | Ukrainian (Ukraine) | Ревматоїдний фактор: Synonyms: Arbitrary concentration; |
| zh-CN | Chinese (China) | 类风湿因子: Synonyms: RF; |
Example Units
| Unit | Source |
|---|---|
| [IU]/mL | Example UCUM Units |
| units/mL | REGENSTRIEF |
33935-8 Cyclic citrullinated peptide IgG Ab [Units/volume] in Serum or Plasma
Part Descriptions
LP29176-2 Cyclic citrullinated peptide
Citrullinated peptide (CCP) is a naturally occurring protein that is produced during the metabolism of ornithine to arginine. CCP proteins are found in synovial tissue of patients with rheumatoid arthritis (RA). High levels of antibodies to CCP have a strong association with RA and are predictive of an aggressive and destructive disease outcome. CCP antibody tests can help diagnose RA when the rheumatoid factor (RF) is negative or below 50 IU/mL.(Pagana, Kathleen Deska, and Timothy James Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. St. Louis, MO: Mosby/Elsevier, 2014. Print.) .) IgA to CCP is more elevated in patients with RA than levels found in healthy individuals or those with other rheumatic diseases. PMID: 18565246
Source: Regenstrief LOINC
LP37860-1 Cyclic citrullinated peptide Ab.IgG
Citrulline is a non-standard amino acid that can be incorporated into proteins only by modification of arginine during a variety of biologic processes including inflammation. Several citrullinated proteins have been demonstrated in the RA synovium. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 0.3 to 1% worldwide and leads to progressive joint erosion and disability if not treated early. Identifying citrullinated epitopes targets led to first and then second generation anti-cyclic citrullinated peptide (anti-CCP) antibody assays. These anti-CCP antibodies are important diagnostic and prognostic markers for rheumatoid arthritis (RA) as they: 1) may be more sensitive than RF (rheumatoid factor) in early and established disease, 2) may be a marker of erosive disease, and 3) may be found in healthy patients years prior to clinical onset, and 4) may predict development of undifferentiated arthritis into RA. PMID: 19427413 PMID: 17558653
Source: Regenstrief LOINC, PMID: 19427413
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Cyclic citrullinated peptide Ab.IgG
- Property
- ACnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- cCP IgG SerPl-aCnc
- Display Name
- Cyclic citrullinated peptide IgG Qn
- Consumer Name Alpha Get Info
- Cyclic citrullinated peptide IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.73
- Change Reason
- Changing system from ser to reflect updates to procedure.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 713
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 46437-0 | Rheumatoid Factor and Cyclic Citrullinated Peptide IgG panel [Units/volume] - Serum |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51009-5 | Cyclic citrullinated peptide Ab.IgG| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Κυκλικό κιτρουλλινιωμένο πεπτίδιο IgG ανοσοσφαιρίνη: Synonyms: Ab IgG |
| es-AR | Spanish (Argentina) | anticuerpo contra péptido cíclico con citrulina.inmunoglobulina G: |
| es-ES | Spanish (Spain) | Peptido cíclico citrulinado IgG: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Péptido cíclico citrulinado Ab.IgG: |
| et-EE | Estonian (Estonia) | Tsükliline tsitrulleeritud peptiid antikehad.IgG: Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Peptide citrulliné cyclique Anticorps. IgG: Synonyms: Anticorps CCP |
| fr-FR | French (France) | Peptide cyclique citrulliné anticorps IgG: |
| fr-CA | French (Canada) | Peptide citrulliné cyclique, IgG: |
| it-IT | Italian (Italy) | Peptide ciclico citrullinato Ab.IgG: Synonyms: anticorpi IgG anticorpo CCP Concentrazione Arbitraria Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| ko-KR | Korean (Korea, Republic Of) | Cyclic citrullinated peptide Antibody.immunoglobulin G: |
| nl-NL | Dutch (Netherlands) | cyclisch citrulline-peptide As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Peptídeo Cíclico Citrulinado Ac.IgG: Synonyms: Immune globulin G; |
| ru-RU | Russian (Russian Federation) | Циклический цитруллинизированный пептид Ат.IgG: Synonyms: Антитело Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Siklik sitrülline peptid Ab.IgG: Synonyms: Ak Ak.IgG |
| uk-UA | Ukrainian (Ukraine) | Циклічний цитруліновий пептид, Антитіла.IgG: Synonyms: ABS; |
| zh-CN | Chinese (China) | 环瓜氨酸肽 抗体.IgG: Synonyms: Ab.IgG; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
| units/mL | REGENSTRIEF |
46435-4 Rheumatoid factor and Cyclic citrullinated peptide IgG Ab [Interpretation] in Serum
Observation Required in Panel
Optional
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Rheumatoid factor & Cyclic citrullinated peptide Ab.IgG
- Property
- Imp
- Time
- Pt
- System
- Ser
- Scale
- Nom
- Method
Additional Names
- Short Name
- RF+cCP IgG Ser-Imp
- Display Name
- Rheumatoid factor and Cyclic citrullinated peptide IgG (S) [Interp]
- Consumer Name Alpha Get Info
- Rheumatoid factor and Cyclic Citrullinated peptide IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.38
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 46437-0 | Rheumatoid Factor and Cyclic Citrullinated Peptide IgG panel [Units/volume] - Serum |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Factor reumatoide+péptido cíclico citrulinado IgG: |
| es-MX | Spanish (Mexico) | Factor reumatoide y péptido cíclico citrulinado Ab.IgG: |
| fr-CA | French (Canada) | Facteur rhumatoïde & peptide citrulliné cyclique, IgG: |
| fr-FR | French (France) | Facteurs rhumatoïdes et peptide cyclique citrulliné anticorps IgG: |
| fr-BE | French (Belgium) | Facteur rhumatoïde & Ac antipeptides cycliques citrullinés Anticorps. IgG: Synonyms: Anticorps CCP RF |
| it-IT | Italian (Italy) | Fattore reumatoide & Peptide ciclico citrullinato Ab.IgG: Synonyms: anticorpi IgG anticorpo CCP FR FR & |
| nl-NL | Dutch (Netherlands) | reumafactor & cyclisch citrullinepeptide As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Fator Reumatóide & Peptídeo Cíclico Citrulinado Ac.IgG: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Ревматоидный фактор & Циклический цитруллинизированный пептид Ат.IgG Ат.IgG: Synonyms: Антитело Впечатление/интерпретация исследования Номинальный; |
| tr-TR | Turkish (Turkey) | Romatoid faktör ve siklik sitrülline peptid Ab.IgG: Synonyms: Ak Ak.IgG |
| zh-CN | Chinese (China) | 类风湿因子与环瓜氨酸肽 抗体.IgG: Synonyms: Ab.IgG; |