55443-6
Deprecated Cardiolipin Ab in Serum
Deprecated
Status Information
- Status
- DEPRECATED
- Comment
- Based on extensive review of mappings and usage across Canada, Canada Health Infoway found that the limited use LABORDER codes are not being used. CHI and the Laboratory LOINC Committee agreed that these codes should be deprecated in order to minimize inadvertent mapping of observations to these terms (as has been reported).
| Map-To | Long Common Name | Mapping Guidance |
|---|---|---|
| 29860-4 | Cardiolipin Ab [Presence] in Serum | |
| 46125-1 | Cardiolipin Ab [Presence] in Serum by Immunoassay | |
| 8062-2 | Cardiolipin Ab [Units/volume] in Serum | |
| 3180-7 | Cardiolipin Ab [Units/volume] in Serum by Immunoassay |
Term Description
Created ONLY for ORDERING in response to request from Canada Health Infoway- a national standardization effort. The dashes in this case mean that the ordering provider does not care what property or scale is used in the observation performed in response to this order. LOINC is still pondering details about how this kind of item should be represented. So the representation might change in the future, but the term will still have the same usage and meaning.
Part Descriptions
LP14126-4 Cardiolipin
Cardiolipin (bisphosphatidyl glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid. It is typically present in metabolically active cells of the heart and skeletal muscle. It has also been observed in certain bacterial membranes. It serves as an insulator and stabilizes the activity of protein complexes important to the electron transport chain. Cardiolipin is a double phospholipid because it has four fatty acid tails, instead of the usual two. Barth syndrome, a rare genetic disorder, is a mutation in the gene coding for tafazzin, an enzyme involved in the biosynthesis of cardiolipin. Females heterozygous for the trait are not affected. Individuals with this condition have abnormal mitochondria and they cannot sustain adequate production of ATP. Cardiomyopathy and general weakness are common to these patients.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Cardiolipin (Wikipedia)
LP21333-7 Cardiolipin Ab
Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases including syphilis, antiphospholipid syndrome, livedoid vasculitis, vertebrobasilar insufficiency, Behçet's syndrome, idiopathic spontaneous abortion, and systemic lupus erythematosus(SLE). They are a form of anti-mitochondrial antibody. In SLE, The anti-DNA antibodies and anti-cardiolipin act independently. In rheumatoid arthritis with systemic sclerosis (scleroderma) these antibodies may tie two conditions together.
Anti-cardiolipin antibodies can be classified in two ways:
As IgM, IgG or IgA
As β2-glycoprotein dependent or independent
In autoimmune disease ACA are beta-2 glycoprotein dependent
syphilis ACA are beta-2 glycoprotein independent and can be assayed using the VDRL test
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Wikipedia
LOINC Names Get Info
- Fully-Specified Name
- Cardiolipin Ab:
-: Pt: Ser: -: - Long Common Name
- Deprecated Cardiolipin Ab in Serum
- Short Name
- Deprecated Cardiolipin Ab Ser
- Display Name
- Cardiolipin Ab (S)
- Consumer Name Alpha Get Info
- Cardiolipin antibody, Blood
Part Model Get Info
Basic Attributes
- Class
- LABORDERS
- Type
- Laboratory
- First Released
- Version 2.27
- Last Updated
- Version 2.66 (DEL)
- Order vs. Observation
- Order
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Kardiolipin Ab: |
| el-GR | Greek (Greece) | Καρδιολιπίνη Αντίσωμα: Synonyms: - LABORDERS Pt Αντίσωμα Καρδιολιπίνη Ορός |
| es-ES | Spanish (Spain) | Cardiolipinas Anticuerpos: |
| es-MX | Spanish (Mexico) | Cardiolipin Ab: |
| et-EE | Estonian (Estonia) | Kardiolipiin antikehad: Synonyms: Juhuslik Seerum |
| fr-CA | French (Canada) | Cardiolipine, Ac: |
| fr-FR | French (France) | Cardiolipine Ac: |
| fr-BE | French (Belgium) | Cardiolipine Ac: Synonyms: Anticorps Demande de laboratoire, prescription analyses labo |
| it-IT | Italian (Italy) | Cardiolipina Ab: Synonyms: anticorpo Codici richieste di laboratorio Punto nel tempo (episodio) Siero |
| nl-NL | Dutch (Netherlands) | cardiolipine As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Kardiolipina Ab: |
| pt-BR | Portuguese (Brazil) | Cardiolipina Ac: Synonyms: ACA; |
| ru-RU | Russian (Russian Federation) | Кардиолипин Ат: Synonyms: Антитело Сыворотка Точка во времени; |
| zh-CN | Chinese (China) | 心磷脂 抗体: Synonyms: Ab; |
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LOINC Copyright
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