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Part Description

LP212220-0   Microsatellite markers exhibiting instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Microsatellite markers exhibiting instability:Num:Pt:Cancer specimen:Qn:
Long Common Name
Microsatellite markers exhibiting instability [#] in Cancer specimen
Short Name
MSI mark found Ca spec
Display Name
Microsatellite markers exhibiting instability (Cancer specimen) [#]
Consumer Name Alpha Get Info
Microsatellite markers exhibiting instability, Cancer specimen

Part Model Get Info

  • Component
    Microsatellite markers exhibiting instability
    LP212220-0
    • Analyte
      Microsatellite markers exhibiting instability
      LP212220-0
      • Component Numerator
        Microsatellite markers exhibiting instability
        LP212220-0
        • Component Numerator Core
          Microsatellite markers exhibiting instability
          LP212220-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Num
    LP6841-3
  • Time
    Pt
    LP6960-1
  • System
    Cancer specimen
    LP247830-5
    • System Core
      Cancer specimen
      LP247830-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.61 (MAJ)
Change Reason
Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
85905-8Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Markery mikrosatelitů signalizující nestabilitu:Počet:Časový bod:Vzorek karcinomu:Kvantitativní:
el-GRGreek (Greece)Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια:Αρ.:Pt:Δείγμα καρκίνου:Qn:
Synonyms: PATH Pt Qn Αρ. Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια
es-ESSpanish (Spain)Marcadores de inestabilidad de microsatelites:Número (recuento):Punto temporal:Muestra de cancer:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Marcadores de microsatélites que presentan inestabilidad:Número (recuento):Punto temporal:Espécimen de cáncer:Cuantitativo:
it-ITItalian (Italy)Marcatori di microsatelliti che dimostrano instabilità:Num:Pt:Campione tumore:Qn:
Synonyms: Campione di tumore Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio)
zh-CNChinese (China)表现不稳定性的微卫星标记:数量(计数):时间点:癌标本:定量型:
Synonyms: 个数;数量;数量或计数（非负整数）;计数 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 样品 样本 癌 癌（癌症、癌变）标本（样本、样品、试样） 表现（展现、体现、显现、显示、存在）不稳定性的微卫星标记 试样

Example Units

UnitSource
{#}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81709-8