Version 2.78

86620-2 Methicillin resistance mecA+mecC genes [Presence] in Nose by NAA with probe detection

Term Description

Detection of the mecA or mecC gene in methicillin-resistant bacteria, specifically methicillin-resistant staphyloccus aureus (MRSA), in various clinical specimens. The result for this term detects the presence of mecA and mecC genes but does not differentiate between them. This term is based on, but not limited in use to, the submitter's Xpert® MRSA NxG assay.
Source: Regenstrief LOINC

Part Descriptions

LP249930-1   Bacterial methicillin resistance mecA+mecC genes
The mecA gene and its homologue, mecC, are found in bacterial cells and enable bacteria to be resistant to antibiotics such as penicillin, oxacillin and other penicillin-like antibiotics. These genes are carried on a mobile genetic element called the staphylococcal cassette chromosome mec (SCCmec), which integrates at an open reading frame (orfX) in the bacterial genome. The most commonly known carrier of the mecA gene is methicillin-resistant Staphylococcus aureus (MRSA). The prevalence of mecC MRSA is currently low but varies geographically where in some regions its presence is increasing. PMID: 24331435 Source: Regenstrief LOINC

LP265773-4   Bacterial ABXBACT probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial methicillin resistance mecA+mecC genes
Property
PrThr
Time
Pt
System
Nose
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
mecA+mecC Nose Ql NAA+probe
Display Name
Methicillin resistance mecA+mecC genes NAA+probe Ql (Nose)
Consumer Name Alpha Get Info
Methicillin resistance mecA+mecC genes, Nose

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.64
Change Reason
Updated Class from "MICRO" to "ABXBACT"
Order vs. Observation
Both

Example Answer List LL3713-6

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8
Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value) LA11885-3
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Member of these Panels

LOINC Long Common Name
104991-5 Bacterial resistance panel
86622-8 MRSA SCCmec and mecA+mecC genes panel - Nose

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bakterielle Methicillin-Resistenz mecA+mecC-Gene:Nachweis oder Schwellenwert:Zeitpunkt:Nase:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) genes bacterianos mecA+mecC meticilin resistentes:PrThr:Punto temporal:Nariz:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Resistencia a la meticilina bacteriana genes mecA + mecC:Presencia o umbral:Punto temporal:Nariz:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Résistance bactérienne à la méticilline mecA+mecC gènes:Présence/Seuil:Ponctuel:Nez:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Resistenza batterica alla meticillina, geni mecA+mecC:PrThr:Pt:Naso:Ord:Sonda.amp.tar
Synonyms: Geni mecA+mecC di resistenza batterica alla metici Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) bacteriële meticillineresistentie mecA + mecC-genen:aanwezigheid:moment:neus:ordinaal:probe-detectie
Synonyms: probe.amp.tar
zh-CN Chinese (China) 细菌甲氧西林耐药 mecA+mecC 基因:存在情况或阈值:时间点:鼻:序数型:探针法.基因扩增.靶向
Synonyms: 2,6-二甲氧基苯青霉素;二甲氧基苯青霉素;二甲氧苯青霉素;新青霉素;甲氧苯青霉素 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分子病理学 - 基因类 基因 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 扩增型 扩增性 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 电阻 细菌性 细菌甲氧西林(2,6-二甲氧基苯青霉素、二甲氧基苯青霉素、二甲氧苯青霉素、新青霉素、甲氧苯青霉素)耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) mecA+mecC 基因 细菌的 经过扩增的 耐性 脱氧核糖核酸探针 阻力 鼻部

77682-3 Staphylococcus aureus methicillin resistance SCCmec+orfX junction [Presence] in Nose by NAA with probe detection

Term Description

This assay is not intended to diagnose MRSA infections nor to guide or monitor treatment. This term was created for, but not limited in use to, the submitter's BD GeneOhm MRSA Assay test kit which directly detects, through the presence of SCCmec cassette at the orfX junction, nasal colonization by methicillin resistant S. aureus (MRSA) to aid in the prevention and control of infections in healthcare settings, for patients at risk.
Source: Regenstrief LOINC

Part Descriptions

LP190755-1   Staphylococcus aureus methicillin resistance SCCmec+orfX junction
Methicillin resistance in S. aureus is primarily mediated by the mecA gene which is carried on a mobile genetic element called the staphylococcal cassette chromosome mec (SCCmec), which integrates at an open reading frame in the S. aureus genome known as orfX. Source: Regenstrief LOINC

Fully-Specified Name

Component
Staphylococcus aureus methicillin resistance SCCmec+orfX junction
Property
PrThr
Time
Pt
System
Nose
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
MRSA SCCmec+orfX Nose Ql NAA+probe
Display Name
MRSA SCCmec+orfX junction NAA+probe Ql (Nose)
Consumer Name Alpha Get Info
MRSA SCCmec+orfX Junction, Nose

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses around SCCmec+orfX in Component based on our current LOINC model.
Order vs. Observation
Both
Common Test Rank Get Info
18681

Example Answer List LL744-4

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Member of these Panels

LOINC Long Common Name
86622-8 MRSA SCCmec and mecA+mecC genes panel - Nose
79448-7 Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus panel - Nose by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Staphylococcus aureus Methicillin-Resistenz SCCmec+orfX junction:Nachweis oder Schwellenwert:Zeitpunkt:Nase:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Staphylococcus aureus resistente a meticilina (SCCmec+orfX):PrThr:Punto temporal:Nariz:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Staphylococo aureus resistencia a la meticilina SCCmec + unión orfX:Presencia o umbral:Punto temporal:Nariz:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Staphylococcus aureus.résistant à la méthicilline SCCmec+orfX jonction:Présence-Seuil:Temps ponctuel:Nez:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Staphylococcus aureus résistance à la méticilline SCCmec+orfX jonction:Présence/Seuil:Ponctuel:Nez:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Staphylococcus aureus meticillino resistente, giunzione (SCCmec+orfX):PrThr:Pt:Naso:Ord:Sonda.amp.tar
Synonyms: Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) Staphylococcus aureus meticillineresistentie (SCCmec+offX) verbinding:aanwezigheid:moment:neus:ordinaal:probe-detectie
Synonyms: MRSA probe.amp.tar
tr-TR Turkish (Turkey) Staphylococcus aureus metisillin dirençli (SCCmec+orfX) birleşme yeri:MevcEşik:Zmlı:Burun:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 金黄色葡萄球菌甲氧西林耐药 SCCmec+orfX 连接部位:存在情况或阈值:时间点:鼻:序数型:探针法.基因扩增.靶向
Synonyms: 2,6-二甲氧基苯青霉素;二甲氧基苯青霉素;二甲氧苯青霉素;新青霉素;甲氧苯青霉素 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 扩增型 扩增性 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 电阻 经过扩增的 耐性 脱氧核糖核酸探针 葡萄状球菌 葡萄球菌属 金葡;金葡菌 金黄色葡萄球菌甲氧西林耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) SCCmec;葡萄球菌盒式染色体 SCCmec;葡萄球菌盒染色体 SCCmec;葡萄球菌染色体 mec 基因盒;SCCmec 基因;葡萄球菌染色体 mec 盒 金黄色葡萄球菌甲氧西林耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) SCCmec+orfX 连接部位 阻力 鼻部