75635-3
Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA
Active
14049-1 Epidermal growth factor [Mass/volume] in Serum or Plasma
Part Descriptions
LP18547-7 Epidermal growth factor
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. EPIDERMAL GROWTH FACTOR exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and epithelial cells.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Epidermal growth factor
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- EGF SerPl-mCnc
- Display Name
- Epidermal growth factor [Mass/Vol]
- Consumer Name Alpha Get Info
- Epidermal growth factor, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7729
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: EGF |
es-AR | Spanish (Argentina) | factor de crecimiento epidérmico: |
es-ES | Spanish (Spain) | Factor de crecimiento epidérmico: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Factor de crecimiento epidérmico: |
et-EE | Estonian (Estonia) | Epidermaalne kasvufaktor: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Facteur de croissance épidermique: |
fr-FR | French (France) | Epidermal growth factor: |
fr-BE | French (Belgium) | Facteur de croissance épidermique: Synonyms: eGF |
it-IT | Italian (Italy) | Fattore di crescita epidermico: Synonyms: Chimica Concentrazione di Massa EGFR Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 표피 성장 인자: |
nl-NL | Dutch (Netherlands) | epidermale groeifactor: |
pt-BR | Portuguese (Brazil) | Fator de crescimento epidermico: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Эпидермальный роста фактор: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Epidermal büyüme faktörü: |
zh-CN | Chinese (China) | 表皮生长因子: Synonyms: EGF 化学; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
1988-5 C reactive protein [Mass/volume] in Serum or Plasma
Part Descriptions
LP15023-2 C reactive protein
C-reactive protein (CRP) is characterized by its precipitation by the C-fraction of pneumococci. This protein is an acute phase reactant and confers immunity against some bacterial infections. CRP is a sensitive and quantitative measurement of the body's acute-phase response. Elevated values are consistent with an acute inflammatory process such as a bacterial infection or rheumatic disease.
Source: Regenstrief Institute
Reference Information
Type | Source | Reference |
---|---|---|
Mapping Guidance | Regenstrief Help | Low sensitivity CRP is used to assess severity of inflammatory diseases such as rheumatoid arthritis. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | C-Reactive Protein (CRP) |
Fully-Specified Name
- Component
- C reactive protein
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- CRP SerPl-mCnc
- Display Name
- CRP [Mass/Vol]
- Consumer Name Alpha Get Info
- C Reactive Protein (CRP), Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 128
Member of these Panels
LOINC | Long Common Name |
---|---|
105456-8 | Anemia evaluation panel - Serum or Blood |
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG6212-7 | C reactive protein| |
LG48228-7 | C reactive protein| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: CRP |
de-DE | German (Germany) | C-reaktives Protein: |
el-GR | Greek (Greece) | C αντιδρώσα πρωτεΐνη: Synonyms: CRP |
es-AR | Spanish (Argentina) | proteína C reactiva: |
es-ES | Spanish (Spain) | Proteína C reactiva: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Proteína C-reactiva: |
et-EE | Estonian (Estonia) | C-reaktiivne valk: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Protéine C réactive: |
fr-FR | French (France) | C Réactive protéine: |
fr-BE | French (Belgium) | Protéine C réactive: Synonyms: CRP |
it-IT | Italian (Italy) | Proteina C reattiva: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | C 반응성 단백: |
nl-NL | Dutch (Netherlands) | C reactief proteïne: |
pt-BR | Portuguese (Brazil) | Proteína C Reativa: Synonyms: ; |
ru-RU | Russian (Russian Federation) | С реактивный протеин: Synonyms: Белок Количественный Массовая концентрация Плазма СРБ; |
tr-TR | Turkish (Turkey) | C reaktif protein: |
uk-UA | Ukrainian (Ukraine) | С-реактивний білок: Synonyms: Chemistry; |
zh-CN | Chinese (China) | C 反应蛋白: Synonyms: C 反应肽; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
mg/L | eCHN |
48498-0 Amyloid A [Mass/volume] in Serum or Plasma
Part Descriptions
LP63040-7 Amyloid A
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL). Different isoforms of SAA are expressed constitutively (constitutive SAAs) at different levels or in response to inflammatory stimuli (acute phase SAAs or A-SAAs). A-SAAs are secreted during the acute phase of inflammation and are implicated in several chronic inflammatory diseases, such as amyloidosis, atherosclerosis, and rheumatoid arthritis. PMID: 15944321 Amyloid A (AA) protein quantification in tissue specimens is a sensitive and specific method for detection of clinical AA amyloidosis. PMID: 17577686
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Amyloid A
Reference Information
Type | Source | Reference |
---|---|---|
Package Insert | Wilhelminenspital | Example package insert. This LOINC code is not constrained to this specific product. BioSource Human Serum Amyloid A (Hu SAA) ELISA |
Fully-Specified Name
- Component
- Amyloid A
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Amyloid A SerPl-mCnc
- Display Name
- Amyloid A [Mass/Vol]
- Consumer Name Alpha Get Info
- Amyloid A, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.70
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Serum - Amyloid A |
de-DE | German (Germany) | Amyloid A: |
es-ES | Spanish (Spain) | Amiloide A: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Amiloide A: |
et-EE | Estonian (Estonia) | Amüloid A: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Amyloïde A: |
fr-FR | French (France) | Protéine amyloïde A: |
fr-BE | French (Belgium) | Amyloïde A: |
it-IT | Italian (Italy) | Amiloide A: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | amyloïd A: Synonyms: amyloid A |
pt-BR | Portuguese (Brazil) | Amilóide A: Synonyms: Mass concentration; |
ru-RU | Russian (Russian Federation) | Амилоид A: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Amiloid A: |
zh-CN | Chinese (China) | 淀粉样蛋白 A: Synonyms: A 型 化学; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
75632-0 Resistin [Mass/volume] in Serum or Plasma
Part Descriptions
LP185757-4 Resistin
Resistin, also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1), is an adipose-derived peptide hormone encoded by the RETN gene. Resistin has been shown to cause high levels of low-density lipoprotein (LDL), increasing the risk of heart disease. It is also associated with inflammatory response.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Resistin
Fully-Specified Name
- Component
- Resistin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Resistin SerPl-mCnc
- Display Name
- Resistin [Mass/Vol]
- Consumer Name Alpha Get Info
- Resistin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.50
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Resistin |
es-ES | Spanish (Spain) | Resistina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Resistir: |
fr-FR | French (France) | Résistine: |
it-IT | Italian (Italy) | Resistina: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | resistine: |
tr-TR | Turkish (Turkey) | Rezistin: |
zh-CN | Chinese (China) | 抵抗素: Synonyms: 化学; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
21365-2 Leptin [Mass/volume] in Serum or Plasma
Part Descriptions
LP19488-3 Leptin
Human Leptin, the 167 amino acid protein hormone of the ob gene, is secreted by adipose tissue and its levels generally correlate with the basal mass index (BMI). As BMI increases so does leptin level. Leptin is used for body mass and energy expenditure, but is also involved as a regulatory molecule in lipid metabolism, hematopoiesis, insulin action, reproductive function, immune function, and angiogenesis. In approximately five percent of the population, the leptin level does not reflect the BMI.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Leptin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Leptin SerPl-mCnc
- Display Name
- Leptin [Mass/Vol]
- Consumer Name Alpha Get Info
- Leptin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3815
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Leptin |
de-DE | German (Germany) | Leptin: |
es-MX | Spanish (Mexico) | Leptina: |
es-AR | Spanish (Argentina) | leptina: |
es-ES | Spanish (Spain) | Leptina: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Leptiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Leptine: |
fr-FR | French (France) | Leptine: |
fr-BE | French (Belgium) | Leptine: |
it-IT | Italian (Italy) | Leptina: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 렙틴: |
nl-NL | Dutch (Netherlands) | leptine: |
pt-BR | Portuguese (Brazil) | Leptina: Synonyms: Mass concentration; |
ru-RU | Russian (Russian Federation) | Лептин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Leptin: |
uk-UA | Ukrainian (Ukraine) | Лептин: Synonyms: Chemistry; |
zh-CN | Chinese (China) | 瘦素: Synonyms: 化学; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
ug/L | eCHN |
48663-9 YKL-40 [Mass/volume] in Serum
Part Descriptions
LP62856-7 YKL-40
YKL-40 is an early diagnostic and prognostic biomarker for ovarian, colorectal and other cancers as well as rheumatoid arthritis and similar debilitating diseases.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- YKL-40
- Property
- MCnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- YKL-40 Ser-mCnc
- Display Name
- YKL-40 (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- YKL-40, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.70
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Proteína YKL-40: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | YKL-40: |
et-EE | Estonian (Estonia) | YKL-40: Synonyms: Juhuslik Kvantitatiivne Seerum |
fr-CA | French (Canada) | YKL-40: |
fr-FR | French (France) | YKL-40: |
fr-BE | French (Belgium) | YKL-40: |
it-IT | Italian (Italy) | YKL-40: Synonyms: Chimica Concentrazione di Massa Punto nel tempo (episodio) Siero |
nl-NL | Dutch (Netherlands) | YKL-40: |
pt-BR | Portuguese (Brazil) | YKL-40: Synonyms: Mass concentration; |
ru-RU | Russian (Russian Federation) | YKL-40: Synonyms: Количественный Массовая концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | YKL-40: |
zh-CN | Chinese (China) | YKL-40: Synonyms: 化学; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
26881-3 Interleukin 6 [Mass/volume] in Serum or Plasma
Part Descriptions
LP16474-6 Interleukin 6
Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene.
IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery. Additionally, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
LP16474-6 Interleukin 6
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 6 is a 25,000 molecular weight glycoprotein produced primarily in macrophages, T cells, fibroblasts and endothelial cells. Its primary target cells are T and B cells and neutrophils. Its main actions are involvement in terminal differentiation of B cells to antibody secreting plasma cells, activation of T cells and stimulation of hepatocyte production of acute phase proteins. Interleukin stimulates Prolactin, Growth Hormone, Luteinizing Hormone, Follicle Stimulating Hormone and ACTH. Release is stimulated by Interleukin 1a and b, Vasoactive Intestinal Polypeptide, and Prostaglandin E2. Release is not affected by aspirin or indomethacin. Levels are elevated in multiple myeloma, rheumatoid arthritis, systemic lupus erythematosus, meningococcus meningitis and infectious peritonitis.
Source: Inter Science Institute, Inter Science Institute
Fully-Specified Name
- Component
- Interleukin 6
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Il6 SerPl-mCnc
- Display Name
- Interleukin 6 [Mass/Vol]
- Consumer Name Alpha Get Info
- Interleukin 6, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1146
Member of these Panels
LOINC | Long Common Name |
---|---|
82335-1 | Cytokines panel - Serum or Plasma |
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Interleukin-6 |
de-DE | German (Germany) | Interleukin-6: Synonyms: IL-6 |
es-MX | Spanish (Mexico) | Interleucina 6: |
es-AR | Spanish (Argentina) | interleucina 6: |
es-ES | Spanish (Spain) | Interleukina 6: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Interleukiin 6: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Interleukine 6: |
fr-FR | French (France) | Interleukine-6: |
fr-BE | French (Belgium) | Interleukine 6: Synonyms: Il6 |
it-IT | Italian (Italy) | Interleuchina 6: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 인터루킨 6: |
nl-NL | Dutch (Netherlands) | interleukine 6: |
pt-BR | Portuguese (Brazil) | Interleucina 6: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Интерлейкин 6: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | İnterlökin 6: |
uk-UA | Ukrainian (Ukraine) | Інтерлейкін 6: Synonyms: B-Cell Differentiation Factor-2; |
zh-CN | Chinese (China) | 白细胞介素 6: Synonyms: B 细胞分化因子-2; |
Example Units
Unit | Source |
---|---|
pg/mL | Example UCUM Units |
pg/mL | REGENSTRIEF |
75628-8 Vascular endothelial growth factor A [Mass/volume] in Serum or Plasma
Part Descriptions
LP185747-5 Vascular endothelial growth factor A
Vascular endothelial growth factor A (VEGF-A) is a member of a sub-family of growth factors, specifically the platelet-derived growth factor family of cystine-knot growth factors. Other members are Placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D. They were discovered later than VEGF-A. Before their discovery, VEGF-A was called just VEGF. Elevated levels of VEGF-A is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in the VEGFA gene that encodes VEGF-A have been associated with proliferative and nonproliferative diabetic retinopathy.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Vascular endothelial growth factor A (VEGF-A)
Fully-Specified Name
- Component
- Vascular endothelial growth factor A
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- VEGF-A SerPl-mCnc
- Display Name
- Vascular endothelial growth factor A [Mass/Vol]
- Consumer Name Alpha Get Info
- Vascular Endothelial Growth Factor A, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.50
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Factor A de crecimiento endotelial vascular: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Factor de crecimiento endotelial vascular A: |
fr-FR | French (France) | VEGF-A: |
it-IT | Italian (Italy) | Fattore A di crescita vascolare endoteliale: Synonyms: Chimica Concentrazione di Massa Fattore A di crescita dellendotelio vascolare Fattore di crescita dell''endotelio vascolare Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | vasculaire endotheliale groeifactor A: |
tr-TR | Turkish (Turkey) | Vasküler endotlyal büyüme faktörü A: |
zh-CN | Chinese (China) | 血管内皮生长因子 A: Synonyms: A 型 VEGF; |
Example Units
Unit | Source |
---|---|
pg/mL | Example UCUM Units |
75627-0 Vascular adhesion protein 1 [Mass/volume] in Serum or Plasma
Part Descriptions
LP185746-7 Vascular adhesion protein 1
Vascular cell adhesion molecule 1 (VCAM-1) is a protein that in humans is encoded by the VCAM1 gene. The VCAM-1 protein mediates the adhesion of lymphocytes, monocytes, eosinophils, and basophils to vascular endothelium. It also functions in leukocyte-endothelial cell signal transduction, and it may play a role in the development of atherosclerosis and rheumatoid arthritis.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, VCAM-1
Fully-Specified Name
- Component
- Vascular adhesion protein 1
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- VAP-1 SerPl-mCnc
- Display Name
- Vascular adhesion protein 1 [Mass/Vol]
- Consumer Name Alpha Get Info
- Vascular adhesion protein 1, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73
- Change Reason
- Release 2.71: COMPONENT: Updated Component from "Vascular cell adhesion molecule 1" per current scientific nomenclature;
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6937
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Molécula 1 de adhesión celular vascular: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Molécula de adhesión de células vasculares 1: |
fr-FR | French (France) | VCAM-1: |
it-IT | Italian (Italy) | Proteina di adesione vascolare 1: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | VCAM-1-eiwit: |
tr-TR | Turkish (Turkey) | Vasküler hüce adezyon molekülü 1: |
zh-CN | Chinese (China) | 血管细胞粘附蛋白 1: Synonyms: Ⅰ I PR; |
Example Units
Unit | Source |
---|---|
ug/mL | Example UCUM Units |
75633-8 Rheumatoid arthritis disease activity score Calculated by VectraDA
Term Description
Rheumatoid arthritis disease activity score is based on the measurements of 12 serum proteins. An algorithm is applied to these concentrations to calculate a quantitative disease activity score ranging from 1 to 100. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with a standard clinical assessment. The test is not intended or validated to diagnose RA. This term is based on Crescendo BioScience's Vectra DA blood test for rheumatoid arthritis disease activity.
Source: Regenstrief LOINC
Part Descriptions
LP185753-3 Rheumatoid arthritis disease activity score
The RA disease activity score is determined by a multi-biomarker disease activity (MBDA) algorithm, which was developed in a series of studies and clinically validated using the DAS28-CRP as a standard. The MBDA algorithm is as follows:
PTJC = Prediction of Tender Joint Count = −26.72+3.243 × [YKL-40]1/10 − 11.97 × [EGF]1/10 + 15.72 × [IL-6]1/10 + 0.4594 × [Leptin]1/10 + 3.881 × [SAA]1/10 + 0.7388 × [TNF-RI]1/10 − 0.2557 × [VCAM-1]1/10 + 0.7003 × [VEGF-A]1/10
PSJC = Prediction of Swollen Joint Count = −26.63 + 3.232 × [YKL-40]1/10 − 11.93 × [EGF]1/10 + 15.67 × [IL-6]1/10 + 0.4578 × [Leptin]1/10 + 3.868 × [SAA]1/10 + 0.7363 × [TNF-RI]1/10 − 0.2548 × [VCAM-1]1/10 + 0.6979 × [VEGF-A]1/10
PPGS = Prediction of Patient Global Score = -13.489 + 5.474 × [IL-6]1/10 + 0.486 × [SAA]1/10 + 2.246 × [MMP-1]1/10 + 1.684 × [Leptin]1/10 + 4.14 × [TNF-RI]1/10 + 2.292 × [VEGF-A]1/10 − 1.898 × [EGF]1/10 + 0.028 × [MMP-3]1/10 − 2.892 × [VCAM-1]1/10 − 0.506 × [Resistin]1/10
MBDA score = round(max(min((0.56 × sqrt(max(PTJC,0)) + 0.28 × sqrt(max(PSJC,0)) + 0.14 × PPGS + 0.36 × log(CRP/106 + 1)) × 10.53 + 1, 100),1))
The biomarker concentrations in the above formulas are expressed in pg/mL. All concentration values (except CRP) are transformed to the power 1/10 prior to use in the algorithm. MBDA scores are integers from 1 to 100 where 1 to 29 are considered low disease activity, 30 to 44 are moderate disease activity, and 45 to 100 are high disease activity. PMID: 22749821
Source: NCBI PubMed, PMID: 22749821
Fully-Specified Name
- Component
- Rheumatoid arthritis disease activity score
- Property
- Score
- Time
- Pt
- System
- Ser/Plas
- Scale
- SemiQn
- Method
- Calculated.VectraDA
Additional Names
- Short Name
- RA DAS Score Calc VectraDA
- Display Name
- Rheumatoid arthritis disease activity score Calculated by VectraDA [Score]
- Consumer Name Alpha Get Info
- Rheumatoid arthritis disease activity score, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 8457
Formula (Readable)
MBDA Score = round (max (min ((0.56 * sqrt (PTJC) + 0.28 * sqrt (PSJC) + 0.14 * PGH + 0.36 * log (CRP/10^6 + 1)) * 10.53 + 1, 100), 1))
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Puntuación de actividad de la enfermedad artritis reumatoide: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Puntuación de actividad de la enfermedad de artritis reumatoide: |
fr-FR | French (France) | Score d'activité de la polyarthrite rhumatoïde: |
it-IT | Italian (Italy) | Artrite reumatoide, punteggio attività: Synonyms: Calcolato mediante VectraDA Chimica Plasma Punteggio attività dell''artrite reumatoide Punto nel tempo (episodio) Siero Siero o Plasma |
zh-CN | Chinese (China) | 类风湿性关节炎疾病活动度评分: Synonyms: Crescendo BioScience Vectra DA 类风湿性关节炎病情活动血液检验项目; |
Example Units
Unit | Source |
---|---|
{score} | Example UCUM Units |
75634-6 Rheumatoid arthritis disease activity score level Qualitative by VectraDA
Term Description
Rheumatoid arthritis disease activity score level is defined as low, moderate or high where scores 1 to 29 are "low" activity level, 30-44 are "moderate" activity level, and 45-100 are "high" activity level. The activity level is based on analysis of multiple biomarkers associated with rheumatoid arthritis. This term was created for Crescendo BioScience's Vectra DA blood test for rheumatoid arthritis disease activity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rheumatoid arthritis disease activity score level
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- VectraDA
Additional Names
- Short Name
- RA DAS level Ql VectraDA
- Display Name
- Rheumatoid arthritis disease activity score level VectraDA Ql [Interp]
- Consumer Name Alpha Get Info
- Rheumatoid arthritis disease activity score level, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.52
- Order vs. Observation
- Observation
Normative Answer List LL2998-4
Answer | Code | Score | Answer ID |
---|---|---|---|
Low | LA9194-7 | ||
Moderate | LA6751-7 | ||
High | LA9193-9 |
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Nivel de puntuación de la actividad de la enfermedad artritis reumatoide: |
es-MX | Spanish (Mexico) | Nivel de puntuación de actividad de la enfermedad de artritis reumatoide: |
fr-FR | French (France) | Score d'activité de la polyarthrite rhumatoïde seuil: |
it-IT | Italian (Italy) | Artrite reumatoide, livello punteggio attività: Synonyms: Chimica Impressione/interpretazione di studio Livello punteggio attività dell''artrite reumatoid Plasma Punteggio attività dell''artrite reumatoide Punto nel tempo (episodio) Siero Siero o Plasma |
zh-CN | Chinese (China) | 类风湿性关节炎疾病活动度评分级别: Synonyms: Crescendo BioScience Vectra DA 类风湿性关节炎病情活动血液检验项目; |
76064-5 Rheumatoid arthritis disease activity score confidence interval by VectraDA
Term Description
The disease activity score (DAS) confidence interval range (e.g. 44.5 - 49.5) reflects the precision of a patient's DAS score (e.g. 47) based on repeat measurements. This term was created for Crescendo BioScience's Vectra DA blood test for rheumatoid arthritis disease activity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rheumatoid arthritis disease activity score confidence interval
- Property
- ScoreRange
- Time
- Pt
- System
- Ser/Plas
- Scale
- SemiQn
- Method
- VectraDA
Additional Names
- Short Name
- RA DAS CI VectraDA
- Display Name
- Rheumatoid arthritis disease activity score confidence interval VectraDA [Score range]
- Consumer Name Alpha Get Info
- Rheumatoid arthritis disease activity score confidence interval, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 9340
Member of these Panels
LOINC | Long Common Name |
---|---|
75635-3 | Rheumatoid arthritis disease activity panel - Serum or Plasma by VectraDA |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Puntuación Intervalo de confianzade la actividad de la enfermedad artritis reumatoide: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Intervalo de confianza de la puntuación de actividad de la enfermedad de artritis reumatoide: |
fr-FR | French (France) | Score d'activité de la polyarthrite rhumatoïde intervalle de confiance: |
it-IT | Italian (Italy) | Artrite reumatoide, intervallo di confidenza punteggio attività: Synonyms: Chimica Gamma di punteggio Intervallo di confidenza punteggio attività dell'' Plasma Punteggio attività dell''artrite reumatoide Punto nel tempo (episodio) Siero Siero o Plasma |
zh-CN | Chinese (China) | 类风湿性关节炎疾病活动度评分可信区间: Synonyms: Crescendo BioScience Vectra DA 类风湿性关节炎病情活动血液检验项目; |