95121-0
Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Chromogenic method
Active
3207-8 Coagulation factor VIII inhibitor [Presence] in Platelet poor plasma by Chromogenic method
Part Descriptions
LP29023-6 Coagulation factor VIII inhibitor
Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites PMID: 23610614.
Source: Regenstrief LOINC
LP14587-7 Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Coagulation factor VIII inhibitor
- Property
- PrThr
- Time
- Pt
- System
- PPP
- Scale
- Ord
- Method
- Chromo
Additional Names
- Short Name
- Fact VIII Inhib PPP Ql Chro
- Display Name
- Coagulation factor VIII inhibitor Chromogenic method Ql (PPP)
- Consumer Name Alpha Get Info
- Coagulation Factor VIII Inhibitor, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.67
- Change Reason
- Release 2.67: COMPONENT: Component changed from Ab to Inhibitor to reflect functional method.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
95121-0 | Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Chromogenic method |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Factor de coagulación VIII inhibido: |
es-AR | Spanish (Argentina) | [anticuerpo anti - ] factor de coagulación VIII: |
es-MX | Spanish (Mexico) | Inhibidor del factor VIII de la coagulación: |
et-EE | Estonian (Estonia) | VIII faktori inhibiitor: Synonyms: Järgarvuline Juhuslik Trombotsüütidevaene plasma |
fr-BE | French (Belgium) | Inhibiteur du facteur VIII: Synonyms: F VIII |
fr-FR | French (France) | Facteur VIII inhibiteur: |
fr-CA | French (Canada) | Inhibiteur du facteur VIII: |
it-IT | Italian (Italy) | Fattore di coagulazione VIII, inibitore: Synonyms: Cromogenico (Enzima) Inibitore del fattore di coagulazione VIII Plasma povero di piastrine Presenza o Soglia Punto nel tempo (episodio) Studio di coagulazione |
ko-KR | Korean (Korea, Republic Of) | 응고 인자 VIII 항체: |
nl-NL | Dutch (Netherlands) | stollingsfactor VIII remmer: Synonyms: coagulatiemethode |
pl-PL | Polish (Poland) | Inhibitor Czynnika krzepnięcia VIII: Synonyms: PPP |
pt-BR | Portuguese (Brazil) | Fator de coagulação VIII Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Коагуляции фактор VIII ингибитор: Synonyms: Обеднённая пластинками плазма; |
tr-TR | Turkish (Turkey) | Koagülasyon faktörü VIII inhibitörü: Synonyms: Mevcut |
zh-CN | Chinese (China) | 凝血因子 VIII 抑制剂: Synonyms: AHF; |
49865-9 Coagulation factor VIII activity actual/normal in Platelet poor plasma by Chromogenic method
Part Descriptions
LP14587-7 Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Coagulation factor VIII activity actual/Normal
- Property
- RelACnc
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
- Chromo
Additional Names
- Short Name
- Fact VIII Act/Nor PPP Chro
- Display Name
- Coagulation factor VIII activity actual/normal Chromogenic method (PPP) [Rel units/Vol]
- Consumer Name Alpha Get Info
- Coagulation Factor VIII Activity actual/normal, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5194
Member of these Panels
LOINC | Long Common Name |
---|---|
95121-0 | Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Chromogenic method |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Faktor VIII Akt. chr |
de-DE | German (Germany) | Gerinnungsfaktor VIII-Aktivität aktuell/normal: Synonyms: Faktor VIII |
es-ES | Spanish (Spain) | Actividad del factor VIII de coagulación actual/normal: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Actividad del factor VIII de coagulación real / normal: |
et-EE | Estonian (Estonia) | VIII faktori aktiivsus tegelik/normaalne: Synonyms: Juhuslik Kvantitatiivne Suhteline kokkuleppeline kontsentratsioon Trombotsüütidevaene plasma |
fr-BE | French (Belgium) | Facteur VIII Activité Mesuré/normal: Synonyms: F VIII F VIII.Activité Mesuré/normal |
fr-FR | French (France) | Facteur VIII activité Patient (%): |
fr-CA | French (Canada) | Facteur VIII Activité , Mesuré/normal: |
it-IT | Italian (Italy) | Fattore di coagulazione VIII, attività effettivo/normale: Synonyms: Attività del fattore di coagulazione VIII Concentrazine Arbitraria Relativa Cromogenico (Enzima) Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione |
nl-NL | Dutch (Netherlands) | stollingsfactor VIII activiteit gemeten/normaal: Synonyms: coagulatiemethode gemeten/normaal |
pl-PL | Polish (Poland) | Aktywność czynnika krzepnięcia VIII badane/prawidłowe: Synonyms: Aktywność czynnika VIII krzepnięcia oznaczona/prawidłowa PPP |
pt-BR | Portuguese (Brazil) | Fator de coagulação VIII atividade verdadeira/Normal: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Коагуляция фактор VIII активность актуальный/нормальный: Synonyms: Количественный Обеднённая пластинками плазма; |
tr-TR | Turkish (Turkey) | Koagülasyon faktörü VIII aktivitesi gerçek/normal: |
uk-UA | Ukrainian (Ukraine) | Коагуляційний фактор VIII активність фактична/Нормальна: Synonyms: Act/Nor; |
zh-CN | Chinese (China) | 凝血因子 VIII 活性 实际的/正常的: Synonyms: AHF; |
93450-5 Coagulation factor VIII inhibitor [Units/volume] in Platelet poor plasma by Chromogenic method
Term Description
This term is created for but not restricted in use to a Nijmegen modification of the classic Bethesda inhibitor titration assay using a chromogenic method. The use of a chromogenic method allows factor VIII inhibitor to be detected in patients receiving emicizumab / Hemlibra®, a therapeutic that interferes with standard clot-based methods PMID: 29446525.
Source: Regenstrief LOINC
Part Descriptions
LP29023-6 Coagulation factor VIII inhibitor
Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites PMID: 23610614.
Source: Regenstrief LOINC
LP14587-7 Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Coagulation factor VIII Inhibitor
- Property
- ACnc
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
- Chromo
Additional Names
- Short Name
- Fact VIII Inhib PPP Chro-aCnc
- Display Name
- Coagulation factor VIII inhibitor Chromogenic method Qn (PPP)
- Consumer Name Alpha Get Info
- Coagulation Factor VIII Inhibitor, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
95121-0 | Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Chromogenic method |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Gerinnungsfaktor VIII-Inhibitor: |
es-ES | Spanish (Spain) | Factor de coagulación VIII inhibido: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Inhibidor del factor VIII de la coagulación: |
et-EE | Estonian (Estonia) | VIII faktori inhibiitor: Synonyms: Juhuslik Kvantitatiivne Trombotsüütidevaene plasma |
fr-CA | French (Canada) | Inhibiteur du facteur VIII: |
fr-BE | French (Belgium) | Inhibiteur du facteur VIII: Synonyms: F VIII |
fr-FR | French (France) | Facteur VIII inhibiteur: |
it-IT | Italian (Italy) | Fattore di coagulazione VIII, inibitore: Synonyms: Concentrazione Arbitraria Cromogenico (Enzima) Inibitore del fattore di coagulazione VIII Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione |
nl-NL | Dutch (Netherlands) | stollingsfactor VIII remmer: Synonyms: coagulatiemethode |
pl-PL | Polish (Poland) | Inhibitor Czynnika krzepnięcia VIII: Synonyms: PPP |
ru-RU | Russian (Russian Federation) | Коагуляции фактор VIII ингибитор: Synonyms: Количественный Обеднённая пластинками плазма; |
tr-TR | Turkish (Turkey) | Koagülasyon faktörü VIII inhibitörü: |
zh-CN | Chinese (China) | 凝血因子 VIII 抑制剂: Synonyms: AHF; |
Example Units
Unit | Source |
---|---|
[beth'U]/mL | Example UCUM Units |
95122-8 Coagulation factor VIII inhibitor [Interpretation] in Platelet poor plasma by Chromogenic method
Part Descriptions
LP29023-6 Coagulation factor VIII inhibitor
Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites PMID: 23610614.
Source: Regenstrief LOINC
LP14587-7 Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Coagulation factor VIII inhibitor
- Property
- Imp
- Time
- Pt
- System
- PPP
- Scale
- Nom
- Method
- Chromo
Additional Names
- Short Name
- Fact VIII Inhib PPP Chro-Imp
- Display Name
- Coagulation factor VIII inhibitor Chromogenic method (PPP) [Interp]
- Consumer Name Alpha Get Info
- Coagulation Factor VIII Inhibitor, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
95121-0 | Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Chromogenic method |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-MX | Spanish (Mexico) | Inhibidor del factor VIII de la coagulación: |
es-ES | Spanish (Spain) | Factor de coagulación VIII inhibido: |
fr-BE | French (Belgium) | Inhibiteur du facteur VIII: Synonyms: F VIII |
fr-CA | French (Canada) | Inhibiteur du facteur VIII: |
fr-FR | French (France) | Facteur VIII inhibiteur: |
it-IT | Italian (Italy) | Fattore di coagulazione VIII, inibitore: Synonyms: Cromogenico (Enzima) Impressione/interpretazione di studio Inibitore del fattore di coagulazione VIII Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione |
nl-NL | Dutch (Netherlands) | stollingsfactor VIII remmer: Synonyms: coagulatiemethode |
ru-RU | Russian (Russian Federation) | Коагуляции фактор VIII ингибитор: Synonyms: Впечатление/интерпретация исследования Номинальный; |
tr-TR | Turkish (Turkey) | Koagülasyon faktörü VIII inhibitörü: |
zh-CN | Chinese (China) | 凝血因子 VIII 抑制剂: Synonyms: AHF; |