21440-3 Human papilloma virus 16+18+31+33+35+45+51+52+56 DNA [Presence] in Cervix by Probe

Term Description

HPV 6 11 42 43 & 44=Low Risk; HPV 16 18 31 33 35 45 51 52 & 56= Intermediate/High Risk
Source: Regenstrief LOINC

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Human papilloma virus 16+18+31+33+35+45+51+52+56 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe

Additional Names

Short Name

HPV I/H Risk DNA Cvx Ql Probe

Display Name

HPV 16+18+31+33+35+45+51+52+56 DNA Probe Ql (Cvx)

Consumer Name Alpha Get Info

HPV 16+18+31+33+35+45+51+52+56, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 1.0m

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list

Order vs. Observation

Both

Common Test Rank Get Info

4162

Example Answer List LL360-9

Member of these Panels

Language Variants Get Info

Related Names

• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV I/H Risk
• HPV16
• HPV16 and 18
• HPV16+18
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Papilloma virus intermediate/high risk
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• UniversalLabOrders

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

30167-1 Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA [Presence] in Cervix by Probe with signal amplification

Part Descriptions

LP28886-7   Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68
The human papilloma viruses (HPVs) belong to the family Papillomaviridae, which are small, nonenveloped deoxyribonucleic acid (DNA) viruses. The HPV genome includes DNA sequences for six early (E1, E2, E4, E5, E6, and E7) and two late (L1 and L2) proteins. There are more than 100 types of HPV. The viruses can be classified into high and low risk types based on their ability to cause cancer. HPV is most often transmitted sexually but has been know to spread during nonsexual encounters and even rarely through fomites. At least 40 HPV types can infect the genital area. Most sexually active persons become infected with HPV at least once. HPV types 16 and 18 are oncogenic, high risk and cause most cervical, penile, vulvar, vaginal, anal and oropharyngeal cancers and precancers. Non oncogenic, low-risk HPV types (e.g., 6, 11) cause genital warts and recurrent respiratory papillomatosis. Since subclinical genital HPV infection generally clears spontaneously, treatment is only directed to the macroscopic (e.g., genital warts) or pathologic HPV-caused precancerous lesions. Cervical cancer is the only HPV-associated cancer for which routine screening is recommended. Vaccines are available to protect against oncogenic as well as common nononcogenic types. PMID: 27127735 [CDC:std/tg2015/hpv] [CDC:std/tg2015/hpv-cancer] Source: Regenstrief LOINC

Fully-Specified Name

Component

Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.sig

Additional Names

Short Name

HPV I/H Risk 1 DNA Cvx Ql Probe+sig amp

Display Name

HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA Probe+sig amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 16+18+31+33+35+39+45+51+52+56+58+59+68, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.04

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

740

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• bDNA
• Bdn-A
• Branched Chain DNA
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HC
• HPA
• HPV
• HPV I/H Risk 1
• HPV IHR
• HPV16
• HPV16 and 18
• HPV16+18
• Human papillomavirus
• Hybidization Protection Assay
• Hybrid Capture
• Hybrid Capture nucleic acid hybridization
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Papilloma virus intermediate/high risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• Probe with signal amplification
• Probe+sig amp
• Ql
• Qual
• Qualitative
• Random
• Screen
• UniversalLabOrders

38372-9 Human papilloma virus 6+11+16+18+31+33+35+39+42+43+44+45+51+52+56+58+59+68 DNA [Presence] in Cervix by Probe with signal amplification

Fully-Specified Name

Component

Human papilloma virus 6+11+16+18+31+33+35+39+42+43+44+45+51+52+56+58+59+68 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.sig

Additional Names

Short Name

HPV DNA Cvx Ql Probe+sig amp

Display Name

HPV 6+11+16+18+31+33+35+39+42+43+44+45+51+52+56+58+59+68 DNA Probe+sig amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 6+11+16+18+31+33+35+39+42+43+44+45+51+52+56+58+59+68, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.14

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

10051

Example Answer List LL360-9

Member of these Panels

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• bDNA
• Bdn-A
• Branched Chain DNA
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HC
• HPA
• HPV
• HPV6
• HPV6+11
• Human papillomavirus
• Hybidization Protection Assay
• Hybrid Capture
• Hybrid Capture nucleic acid hybridization
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus low risk
• Papilloma virus low/intermediate/high risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• Probe with signal amplification
• Probe+sig amp
• Ql
• Qual
• Qualitative
• Random
• Screen

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

42481-2 Human papilloma virus 6+11+42+43+44 DNA [Presence] in Cervix by Probe with signal amplification

Part Descriptions

LP19517-9   Human papilloma virus 6+11+42+43+44
The human papilloma viruses (HPVs) belong to the family Papillomaviridae, which are small, nonenveloped deoxyribonucleic acid (DNA) viruses. The HPV genome includes DNA sequences for six early (E1, E2, E4, E5, E6, and E7) and two late (L1 and L2) proteins. There are more than 100 types of HPV. The viruses can be classified into high and low risk types based on their ability to cause cancer. HPV is most often transmitted sexually but has been know to spread during nonsexual encounters and even rarely through fomites. At least 40 HPV types can infect the genital area. Most sexually active persons become infected with HPV at least once. HPV types 16 and 18 are oncogenic, high risk and cause most cervical, penile, vulvar, vaginal, anal and oropharyngeal cancers and precancers. Non oncogenic, low-risk HPV types (e.g., 6, 11) cause genital warts and recurrent respiratory papillomatosis. Since subclinical genital HPV infection generally clears spontaneously, treatment is only directed to the macroscopic (e.g., genital warts) or pathologic HPV-caused precancerous lesions. Cervical cancer is the only HPV-associated cancer for which routine screening is recommended. Vaccines are available to protect against oncogenic as well as common nononcogenic types. PMID: 27127735 [CDC:std/tg2015/hpv] [CDC:std/tg2015/hpv-cancer] Source: Regenstrief LOINC

Fully-Specified Name

Component

Human papilloma virus 6+11+42+43+44 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.sig

Additional Names

Short Name

HPV Low Risk DNA Cvx Ql Probe+sig amp

Display Name

HPV 6+11+42+43+44 DNA Probe+sig amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 6+11+42+43+44, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.16

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list

Order vs. Observation

Both

Common Test Rank Get Info

3157

Example Answer List LL360-9

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• bDNA
• Bdn-A
• Branched Chain DNA
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HC
• HPA
• HPV
• HPV Low Risk
• HPV6
• HPV6+11
• Human papillomavirus
• Hybidization Protection Assay
• Hybrid Capture
• Hybrid Capture nucleic acid hybridization
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus low risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• Probe with signal amplification
• Probe+sig amp
• Ql
• Qual
• Qualitative
• Random
• Screen
• UniversalLabOrders

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

49896-4 Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA [Presence] in Specimen by NAA with probe detection

Part Descriptions

LP28886-7   Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68
The human papilloma viruses (HPVs) belong to the family Papillomaviridae, which are small, nonenveloped deoxyribonucleic acid (DNA) viruses. The HPV genome includes DNA sequences for six early (E1, E2, E4, E5, E6, and E7) and two late (L1 and L2) proteins. There are more than 100 types of HPV. The viruses can be classified into high and low risk types based on their ability to cause cancer. HPV is most often transmitted sexually but has been know to spread during nonsexual encounters and even rarely through fomites. At least 40 HPV types can infect the genital area. Most sexually active persons become infected with HPV at least once. HPV types 16 and 18 are oncogenic, high risk and cause most cervical, penile, vulvar, vaginal, anal and oropharyngeal cancers and precancers. Non oncogenic, low-risk HPV types (e.g., 6, 11) cause genital warts and recurrent respiratory papillomatosis. Since subclinical genital HPV infection generally clears spontaneously, treatment is only directed to the macroscopic (e.g., genital warts) or pathologic HPV-caused precancerous lesions. Cervical cancer is the only HPV-associated cancer for which routine screening is recommended. Vaccines are available to protect against oncogenic as well as common nononcogenic types. PMID: 27127735 [CDC:std/tg2015/hpv] [CDC:std/tg2015/hpv-cancer] Source: Regenstrief LOINC

Fully-Specified Name

Component

Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA

Property

PrThr

Time

Pt

System

XXX

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

HPV I/H Risk 1 DNA Spec Ql NAA+probe

Display Name

HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA NAA+probe Ql (Specimen)

Consumer Name Alpha Get Info

HPV 16+18+31+33+35+39+45+51+52+56+58+59+68, Specimen

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.22

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

3359

Example Answer List LL360-9

Member of these Panels

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital warts
• HPV
• HPV I/H Risk 1
• HPV IHR
• HPV16
• HPV16 and 18
• HPV16+18
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• Misc
• Miscellaneous
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• Other
• Papilloma virus high risk
• Papilloma virus intermediate/high risk
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• To be specified in another part of the message
• Transcription mediated amplification
• Unspecified

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

59263-4 Human papilloma virus 16 DNA [Presence] in Cervix by Probe with signal amplification

Part Descriptions

LP18037-9   Human papilloma virus 16
HPV type 16 has been associated with low grade cervical abnormalities, cancer precursors, and anogenital cancers. Type 16 is the cause of approximately 50% of cervical cancers worldwide, HPV types 16 and 18 together account for about 70% of cervical cancers. Source: Centers for Disease Control and Prevention, Human papilloma virus 16

Fully-Specified Name

Component

Human papilloma virus 16 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.sig

Additional Names

Short Name

HPV16 DNA Cvx Ql Probe+sig amp

Display Name

HPV 16 DNA Probe+sig amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 16, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.32

Last Updated

Version 2.73

Change Reason

Property changed from ACnc to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

3434

Example Answer List LL360-9

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• bDNA
• Bdn-A
• Branched Chain DNA
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HC
• HPA
• HPV
• HPV16
• Human papillomavirus
• Hybidization Protection Assay
• Hybrid Capture
• Hybrid Capture nucleic acid hybridization
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• Probe with signal amplification
• Probe+sig amp
• Ql
• Qual
• Qualitative
• Random
• Screen

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

59264-2 Human papilloma virus 18 DNA [Presence] in Cervix by Probe with signal amplification

Part Descriptions

LP19179-8   Human papilloma virus 18
HPV type 18 has been associated with low grade cervical abnormalities, cancer precursors, and anogenital cancers. HPV types 16 and 18 together account for about 70% of cervical cancers. Source: Centers for Disease Control and Prevention, Human papilloma virus 18

Fully-Specified Name

Component

Human papilloma virus 18 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.sig

Additional Names

Short Name

HPV18 DNA Cvx Ql Probe+sig amp

Display Name

HPV 18 DNA Probe+sig amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 18, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.32

Last Updated

Version 2.73

Change Reason

Property changed from ACnc to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

5200

Example Answer List LL360-9

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• bDNA
• Bdn-A
• Branched Chain DNA
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HC
• HPA
• HPV
• HPV18
• Human papillomavirus
• Hybidization Protection Assay
• Hybrid Capture
• Hybrid Capture nucleic acid hybridization
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• Probe with signal amplification
• Probe+sig amp
• Ql
• Qual
• Qualitative
• Random
• Screen

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

59420-0 Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+66+68 DNA [Presence] in Cervix by Probe with signal amplification

Fully-Specified Name

Component

Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+66+68 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.sig

Additional Names

Short Name

HPV I/H Risk 4 DNA Cvx Ql Probe+sig amp

Display Name

HPV 16+18+31+33+35+39+45+51+52+56+58+59+66+68 DNA Probe+sig amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 16+18+31+33+35+39+45+51+52+56+58+59+66+68, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.32

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

520

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• bDNA
• Bdn-A
• Branched Chain DNA
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HC
• HPA
• HPV
• HPV I/H Risk 4
• HPV16
• HPV16 and 18
• HPV16+18
• HPV16+18+H Risk 12
• HPV16+18+HRisk12DNA
• Human papillomavirus
• Hybidization Protection Assay
• Hybrid Capture
• Hybrid Capture nucleic acid hybridization
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• Probe with signal amplification
• Probe+sig amp
• Ql
• Qual
• Qualitative
• Random
• Screen

69002-4 Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

Term Description

This term was created for (but not limited to) Gen-Probe's Aptima HPV assay (Cat No. 302610) that detects the E6 and E7 polycistronic mRNA from 14 high-risk HPV genotypes (16,18,31,33,35,39,45,51,52,56,58,59,66,and 68) that can lead to cervical cancer. E6/E7 genes in high-risk HPV genotypes are known as oncogenes because of their continuous expression, which leads to disruption of cell-cycle check points and cell genome instability through alteration of cellular p53 and retinoblastoma protein functions. This test is similar to LOINC 69358-0, which measures cells containing E6+E7 mRNA via flow cytometry.
Source: Regenstrief LOINC

Part Descriptions

LP135722-9   Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+66+68 E6+E7 mRNA
Most human papilloma virus (HPV) genomes encode for eight major proteins, six "early" (E1, E2, E3, E4, E6, and E7) and two "late" (L1 and L2). The "early" are regulatory in function. E6 and E7 genes in high-risk HPV genotypes are known as oncogenes because of their continuous expression, which leads to disruption of cell-cycle check points and cell genome instability through alteration of cellular p53 and retinoblastoma protein functions. Source: Regenstrief LOINC

Fully-Specified Name

Component

Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+66+68 E6+E7 mRNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

HPV E6+E7 mRNA Cvx Ql NAA+probe

Display Name

HPV E6+E7 mRNA NAA+probe Ql (Cvx)

Consumer Name Alpha Get Info

HPV E6+E7 MRNA, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.38

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

1194

Example Answer List LL360-9

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Cervix
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV E6+E7
• HPV E6+E7 mRNA
• HPV I/H Risk 4
• HPV16
• HPV16 and 18
• HPV16+18
• HPV16+18+H Risk 12
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

71431-1 Human papilloma virus 31+33+35+39+45+51+52+56+58+59+66+68 DNA [Presence] in Cervix by NAA with probe detection

Term Description

Of more than 100 types of human papilloma virus, 14 that are considered high-risk for causing cervical cancer are 16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68. HPV 16 and 18 are often reported distinctly, while this test reports the presence of the remaining 12 as a single ordinal.
Source: Regenstrief LOINC

Part Descriptions

LP149287-7   Human papilloma virus 31+33+35+39+45+51+52+56+58+59+66+68 DNA
Oncogenic (high risk) human papillomavirus types behave as carcinogens in the development of cervicalcancer and other anogenital cancers. High risk types (which include types16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 69, 73, 82) can cause low-grade cervical cell abnormalities, high-grade cervical cell abnormalities that are predecessors to cancer, and anogenital cancers. High-risk HPV types are identified in 99% of cervical cancers. Source: Regenstrief LOINC, CDC Pink Book

Fully-Specified Name

Component

Human papilloma virus 31+33+35+39+45+51+52+56+58+59+66+68 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

HPV HR 12 DNA Cvx Ql NAA+probe

Display Name

HPV 31+33+35+39+45+51+52+56+58+59+66+68 DNA NAA+probe Ql (Cvx)

Consumer Name Alpha Get Info

HPV 31+33+35+39+45+51+52+56+58+59+66+68, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.40

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

1668

Example Answer List LL1311-1

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV H Risk 12 DNA
• HPV HR 12
• HPV31
• HPV31+33
• HPV31+33+35
• Human papilloma virus
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Papilloma virus intermediate/high risk
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification
• UniversalLabOrders

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

75406-9 Deprecated Human papilloma virus 16 and 18+45 E6+E7 mRNA [Presence] in Cervix by Probe with amplification

Term Description

Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16, 18, and 45 in cervical specimens from women with positive HPV assay results. For women 21-years and older with atypical squamous cells of undetermined significance (ASC-US) cervical cytology results, and HPV positive assay results, this assay can be used to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. For women 30-years and older, the HPV 16, 18, and/or 45 genotype assay can be used to test samples from women with HPV assay positive results, along with cervical cytology results. This assay has not been evaluated for HPV vaccinated patients or in cases of suspected abuse. It differentiates HPV 16 from HPV 18 and/or HPV 45, but does not differentiate HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated amplification and detection of the amplification products by hybridization protection.
Source: Regenstrief LOINC

Part Descriptions

LP184364-0   Human papilloma virus 16 & 18+45 E6+E7 mRNA
A group of about 30 HPVs, typically transmitted through sexual contact. Genital HPV infection is very common, with estimates suggesting that up to 75% of women will become infected with one or more of the sexually transmitted HPV types at some point during adulthood (Baseman and Koutsky, 2005). Some sexually transmitted HPVs, such as types 6 and 11, can cause genital warts. However, most HPV types that infect the genitals tend not to cause noticeable symptoms. Persistent infection with a subset of about a dozen so-called high-risk sexually transmitted HPVs, including types 16,18,31, and 33, can lead to the development of anogenital cancers, including cervical, penile and anal. HPV infection is a necessary factor in the development of nearly all cases of cervical cancer (Walboomers 1999). Cervical Pap smear testing is used to detect HPV-induced cellular abnormalities. This allows targeted surgical removal of pre-cancerous lesions prior to the development of invasive cervical cancer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Human papilloma virus (Wikipedia)

Fully-Specified Name

Component

Human papilloma virus 16 & 18+45 E6+E7 mRNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp

Additional Names

Short Name

Deprecated HPV16+18+45 E6+E7mRNA Cervix

Display Name

HPV 16 and 18+45 E6+E7 mRNA Probe amp Ql (Cvx)

Consumer Name Alpha Get Info

HPV 16 and 18+45 E6+E7 MRNA, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.50

Last Updated

Version 2.58

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Example Answer List LL2997-6

Member of these Panels

Language Variants Get Info

Related Names

• Amplif
• Amplification
• Amplified
• Cervix
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV 16 & 18+45
• HPV16
• HPV16 and 18
• HPV16+18
• HPV16+18+45 E6+E7mRNA
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• Point in time
• PR
• Probe amp
• Probe with ampification
• QL
• Qual
• Qualitative
• Random
• Screen

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

77379-6 Human papilloma virus 16 and 18 and 31+33+35+39+45+51+52+56+58+59+66+68 DNA [Interpretation] in Cervix

Part Descriptions

LP149290-1   Human papilloma virus 16 & 18 & 31+33+35+39+45+51+52+56+58+59+66+68
Test is for the qualitative detection of 14 high risk Human Papillomavirus (HPV) types primarily in cervical or endocervical swab specimens by amplification of target DNA and nucleic acid hybridization. Submitter's test, the cobas® HPV Test, specifically identifies types HPV16 and HPV18 while concurrently detecting 12 other high risk types (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68). The test is based on two major processes: (1) automated specimen preparation to simultaneously extract HPV and cellular DNA; (2) PCR amplification of target DNA sequences using both HPV and β-globin specific complementary primer pairs and real-time detection of cleaved fluorescent-labeled HPV and β-globin specific oligonucleotide detection probes. Primers used define a sequence of approximately 200 nucleotides within the polymorphic L1 region of the HPV genome. Source: Regenstrief LOINC

Fully-Specified Name

Component

Human papilloma virus 16 & 18 & 31+33+35+39+45+51+52+56+58+59+66+68 DNA

Property

Imp

Time

Pt

System

Cvx

Scale

Nom

Method

Additional Names

Short Name

HPV16+18+H Risk 12 DNA Cvx-Imp

Display Name

HPV 16 and 18 and 31+33+35+39+45+51+52+56+58+59+66+68 DNA (Cvx) [Interp]

Consumer Name Alpha Get Info

HPV 16 and 18 and 31+33+35+39+45+51+52+56+58+59+66+68, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.52

Last Updated

Version 2.73

Change Reason

Changed 'papiloma' to 'papilloma' to correct the spelling.

Order vs. Observation

Observation

Common Test Rank Get Info

9212

Example Answer List LL3274-9

Member of these Panels

Language Variants Get Info

Related Names

• Cervix
• Deoxyribonucleic acid
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV I/H Risk 4
• HPV16
• HPV16 and 18
• HPV16+18
• HPV16+18+H Risk 12
• HPV16+18+HRisk12DNA
• Human papillomavirus
• ID
• Impression
• Impression/interpretation of study
• Impressions
• Infectious Disease
• InfectiousDisease
• Interp
• Interpretation
• Microbiology
• Nominal
• OB
• ObGyn
• Obstetrics
• Papilloma virus high risk
• Point in time
• Random

77399-4 Human papilloma virus 16 DNA [Presence] in Cervix by NAA with probe detection

Part Descriptions

LP18037-9   Human papilloma virus 16
HPV type 16 has been associated with low grade cervical abnormalities, cancer precursors, and anogenital cancers. Type 16 is the cause of approximately 50% of cervical cancers worldwide, HPV types 16 and 18 together account for about 70% of cervical cancers. Source: Centers for Disease Control and Prevention, Human papilloma virus 16

Fully-Specified Name

Component

Human papilloma virus 16 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

HPV16 DNA Cvx Ql NAA+probe

Display Name

HPV 16 DNA NAA+probe Ql (Cvx)

Consumer Name Alpha Get Info

HPV 16, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.52

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

5271

Example Answer List LL2978-6

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV16
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

77400-0 Human papilloma virus 18 DNA [Presence] in Cervix by NAA with probe detection

Part Descriptions

LP19179-8   Human papilloma virus 18
HPV type 18 has been associated with low grade cervical abnormalities, cancer precursors, and anogenital cancers. HPV types 16 and 18 together account for about 70% of cervical cancers. Source: Centers for Disease Control and Prevention, Human papilloma virus 18

Fully-Specified Name

Component

Human papilloma virus 18 DNA

Property

PrThr

Time

Pt

System

Cvx

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

HPV18 DNA Cvx Ql NAA+probe

Display Name

HPV 18 DNA NAA+probe Ql (Cvx)

Consumer Name Alpha Get Info

HPV 18, Cervix

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.52

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

6619

Example Answer List LL2978-6

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Cervix
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Genital tract
• Genital warts
• Gyn
• Gynecology
• HPV
• HPV18
• Human papillomavirus
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• OB
• ObGyn
• Obstetrics
• Ordinal
• Papilloma virus high risk
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification