97326-3
Staphylococcus aureus identification and resistance panel by Molecular genetics method
Active
75756-7 Bacteria identified in Isolate by MS.MALDI-TOF
Term Description
Bacterial identification by MALDI-TOF (matrix-assisted laser desorption ionization time of flight) is a diagnostic test for identifying the specific organism(s) responsible for a bacterial infection. MALDI-TOF is a form of mass spectrometry that analyzes the proteins contained in an isolated bacterial colony. The resulting mass spectrum is compared to a reference database of bacterial protein mass spectra in order to identify the organism(s) present in the test sample. This term was created for, but is not limited in use to, the Bruker Daltonics MALDI Biotyper CA System, which is indicated for use in diagnosing Gram-negative bacterial infections.
Source: Regenstrief LOINC
Part Descriptions
LP14082-9 Bacteria
One of the three domains of life (the others being Eukarya and Archaea), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls and multiply by cell division. They exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to oxygen (aerobic, anaerobic, or facultatively anaerobic) and by how they obtain their energy (chemotrophic, i.e. via a chemical reaction or phototrophic, via a light reaction). In addition, chemotrophs obtain their energy from chemicals, lithotrophic from inorganic compounds and organotrophic from organic compounds. Bacteria are also classified by the source carbon that they utilize: heterotrophic, from organic sources or autotrophic, from carbon dioxide. They can also be classified by whether or not they stain (based on the structure of their cell walls) with crystal violet dye: gram-negative or gram-positive.
Source: National Library of Medicine, MeSH 2006
LP186074-3 MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373
Source: Regenstrief LOINC, PMID: 23824373
Fully-Specified Name
- Component
- Bacteria
- Property
- Prid
- Time
- Pt
- System
- Isolate
- Scale
- Nom
- Method
- MS.MALDI-TOF
Additional Names
- Short Name
- Bacteria Islt MS.MALDI-TOF
- Display Name
- Bacteria identified MS.MALDI-TOF Nom (Isol)
- Consumer Name Alpha Get Info
- Bacterial test
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.78
- Change Reason
- Release 2.78: COMPONENT: Removed "Identified" from the component because it is implied by the Property "Prid";
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 13359
Example Answer List LL2991-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Escherichia coli Copyright http://snomed.info/sct ID:112283007 Escherichia coli (organism) | LA21335-7 | ||
| Klebsiella pneumoniae | LA21336-5 | ||
| Salmonella sp | LA21368-8 | ||
| Pseudomonas aeruginosa | LA19340-1 | ||
| Enterobacter cloacae | LA21369-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 97324-8 | Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method |
| 97326-3 | Staphylococcus aureus identification and resistance panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Bakterien identifiziert: Synonyms: Matrix-assisted laser desorption/ionization - Time-of-Flight-Massenspektrometrie |
| es-MX | Spanish (Mexico) | Bacterias identificadas: |
| es-ES | Spanish (Spain) | Bacteria: |
| fr-FR | French (France) | Bactérie identifiée: |
| it-IT | Italian (Italy) | Batteri: Synonyms: Microbiologia Presenza o Identità Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | bacteriën: Synonyms: bacterie massaspectometrie; |
| zh-CN | Chinese (China) | 细菌: Synonyms: 分离物; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
48816-3 Staphylococcus aureus Panton-Valentine leukocidin gene [Presence] in Isolate or Specimen by Molecular genetics method
Term Description
The test is for the detection of the 2 genes that cause S.aureus to produce the PVL cytotoxin.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Staphylococcus aureus Panton-Valentine leukocidin gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- S aureus PVL gene Islt/Spm Ql
- Display Name
- S. aureus Panton-Valentine leukocidin gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Staphylococcus aureus panton-Valentine leukocidin gene
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Change Reason
- Release 2.70: METHOD_TYP: Updated Method from Probe.amp.tar to allow use for other molecular methods and decrease redundancy; SYSTEM: Updated System from XXX for consistency with other bacterial resistance terms; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 15279
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 97326-3 | Staphylococcus aureus identification and resistance panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Staphylococcus aureus PVL-Gen ql. /SM PCR |
| de-DE | German (Germany) | Staphylococcus aureus Panton-Valentine-leukocidin-Gene: |
| es-MX | Spanish (Mexico) | Gen de la leucocidina de Staphylococo aureus Panton-Valentine: |
| es-ES | Spanish (Spain) | Gen Panton-Valentine leukocidina de Staphylococcus aureus: |
| fr-FR | French (France) | Staphylococcus aureus leucocidine de Panton-Valentine gène: |
| fr-CA | French (Canada) | Staphylococcus aureus porteur du gène leucocidine de Panton-Valentine: |
| it-IT | Italian (Italy) | Staphylococcus aureus, gene leucocidina Panton-Valentine: Synonyms: Gene di leucocidina Panton-Valentine di Staphyloco Genetica molecolare Isolato o Campione Microbiologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | Staphylococcus aureus Panton-Valentine-leukocidinegen: Synonyms: isolaat/specimen molgen |
| pt-BR | Portuguese (Brazil) | Staphylococcus aureus Panton-Valentine leukocidin gene: Synonyms: ; |
| zh-CN | Chinese (China) | 金黄色葡萄球菌 Panton-Valetine 杀白细胞素基因: Synonyms: Panton-Valentine 杀白细胞素（Panton-Valentine leukocidin， |
48813-0 Methicillin resistance mecA gene [Presence] by Molecular method
Fully-Specified Name
- Component
- Bacterial methicillin resistance mecA gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- mecA Islt/Spm Ql
- Display Name
- Methicillin resistance mecA gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Methicillin resistance mecA gene
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses around gene name in Component based on the current LOINC model.; ; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3578
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104991-5 | Bacterial resistance panel |
| 85762-3 | Blood pathogens panel by NAA with non-probe detection in Positive blood culture |
| 76586-7 | ENT microorganism gene identification panel by NAA with probe detection |
| 92789-7 | Gram positive blood culture panel by NAA with probe detection in Positive blood culture |
| 72892-3 | MRSA SCCmec and mecA genes panel - Nose by NAA with probe detection |
| 97326-3 | Staphylococcus aureus identification and resistance panel by Molecular genetics method |
| 99012-7 | Urinary tract pathogens panel - Urine by NAA with probe detection |
| 76585-9 | Wound microorganism gene identification panel by NAA with probe detection |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Methicillin Resistenz Gen (MecA) ql. |
| de-DE | German (Germany) | Bakterielle Methicillin-Resistenz mecA-Gen: |
| es-ES | Spanish (Spain) | Gen mecA bacterias meticilin resistente: |
| es-MX | Spanish (Mexico) | Gen mecA de resistencia a la meticilina bacteriana: |
| fr-CA | French (Canada) | Gène bactérien de résistance à la méthicilline mecA: |
| fr-FR | French (France) | Résistance bactérienne à la méticilline mecA gène: |
| it-IT | Italian (Italy) | Gene mecA di resistenza batterica a meticillina: Synonyms: Gene mecA Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | bacteriële meticillineresistentie mecA-gen: Synonyms: isolaat/specimen molgen |
| pt-BR | Portuguese (Brazil) | mecA gene: Synonyms: Methicillin resistance gene; |
| zh-CN | Chinese (China) | 细菌甲氧西林耐药 mecA 基因: Synonyms: 2,6-二甲氧基苯青霉素; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
86621-0 Methicillin resistance mecC gene [Presence] by Molecular method
Term Description
Detection of the mecC gene in methicillin-resistant bacteria, specifically methicillin-resistant staphyloccus aureus (MRSA), in various clinical specimens.
Source: Regenstrief LOINC
Part Descriptions
LP249928-5 Bacterial methicillin resistance mecC gene
The mecC gene, a homologue of mecA, is found in bacterial cells and enable bacteria to be resistant to antibiotics such as oxacillin. The gene is carried on a mobile genetic element called the staphylococcal cassette chromosome mec (SCCmec), which integrates at an open reading frame (orfX) in the bacterial genome. Detection of the gene in clinical specimens suggests the presence of methicillin-resistant bacteria, primarily Staphylococcus aureaus (MRSA). The prevalence of mecC MRSA is currently low but varies geographically where in some regions its presence is increasing. PMID: 24331435
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Bacterial methicillin resistance mecC gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- MRB mecC Islt/Spm Ql
- Display Name
- Methicillin resistance mecC gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Methicillin resistance mecC gene
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.65
- Change Reason
- Updated Class from "MICRO" to "ABXBACT"; Updated System from "XXX" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Both
Example Answer List LL956-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 | ||
| Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value) | LA11885-3 | ||
| Inconclusive Copyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104991-5 | Bacterial resistance panel |
| 92789-7 | Gram positive blood culture panel by NAA with probe detection in Positive blood culture |
| 97326-3 | Staphylococcus aureus identification and resistance panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Bakterielle Methicillin-Resistenz mecC-Gen: |
| de-AT | German (Austria) | Synonyms: Methicillin Resistenz Gen (MecC) ql. |
| es-MX | Spanish (Mexico) | Gen mecC de resistencia a la meticilina bacteriana: |
| es-ES | Spanish (Spain) | gen bacteriano mecC meticilin resistentes: |
| fr-FR | French (France) | Résistance bactérienne à la méticilline mecC gène: |
| it-IT | Italian (Italy) | Resistenza batterica alla meticillina, gene mecC: Synonyms: Gene mecC di resistenza batterica alla meticillina Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | bacteriële meticillineresistentie mecC-gen: Synonyms: isolaat/specimen molgen |
| zh-CN | Chinese (China) | 细菌甲氧西林耐药 mecC 基因: Synonyms: 2,6-二甲氧基苯青霉素; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
97325-5 Staphylococcus aureus VNTR pattern [Type] in Isolate or Specimen by Molecular genetics method
Part Descriptions
LP420888-2 Staphylococcus aureus VNTR pattern
Staphylococcus aureus (SA) multiple locus variable number tandem repeat analysis (VNTR) is a molecular typing method used to assign biologically meaningful genotypes and complexes to SA. Unlike other resource intensive typing methods, MLVA is a high throughput low cost method that aids in the study of the routes and rates of SA transmission. MLVA may play a future role in advancing hospital, national, and international epidemiology. PMID: 19343175
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Staphylococcus aureus VNTR pattern
- Property
- Type
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Nom
- Method
- Molgen
Additional Names
- Short Name
- SA VNTR patt Islt/Spm
- Display Name
- S. aureus VNTR pattern Molgen Nom (Islt/Spec)
- Consumer Name Alpha Get Info
- Staphylococcus aureus VNTR pattern
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.70
- Last Updated
- Version 2.70
- Order vs. Observation
- Observation
Example Answer List LL5863-7
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| 14-00-02-03-02-12-06-06 | LA31947-7 | ||
| 18-05-03-01-01-10-01-05 | LA31948-5 | ||
| 12-03-03-05-01-11-01-04 | LA31949-3 | ||
| 18-05-03-01-01-12-01-05 | LA31950-1 | ||
| 12-03-03-05-01-11-02-03 | LA31951-9 | ||
| 14-02-01-03-02-07-05-05 | LA31952-7 | ||
| 12-02-02-05-01-11-02-04 | LA31953-5 | ||
| 12-01-01-02-01-10-02-04 | LA31954-3 | ||
| 12-01-01-02-01-09-02-05 | LA31955-0 | ||
| 16-01-01-05-01-11-07-06 | LA31956-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 97326-3 | Staphylococcus aureus identification and resistance panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Patrón VNTR de Staphylococcus aureus: |
| es-ES | Spanish (Spain) | Patrón VNTR de Staphylococcus aureus: |
| fr-FR | French (France) | Staphylococcus aureus VNTR profil: |
| it-IT | Italian (Italy) | Staphylococcus aureus VNTR, profilo: Synonyms: Genetica molecolare Isolato o Campione Microbiologia Profilo di staphylococcus aureus VNTR Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | Staphylococcus aureus VNTR-patroon: Synonyms: isolaat/specimen molgen |
| zh-CN | Chinese (China) | 金黄色葡萄球菌 VNTR 模式: Synonyms: 供检查用的材料; |
94512-1 Staphylococcus aureus and Methicillin Resistant Staphylococcus aureus identified in Isolate or Specimen by Molecular genetics method
Term Description
Detection of Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA) DNA in isolates or clinical specimens by molecular methods. This term was created for, but not limited in use to, the Cephid Xpert MRSA/SA Skin and Soft Tissue Infection Assay (Xpert MRSA/SA SSTI Assay), which is indicated for use in conjunction with other laboratory tests to aid in the detection of MRSA/SA.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Staphylococcus aureus & Staphylococcus aureus.methicillin resistant identified
- Property
- Prid
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Nom
- Method
- Molgen
Additional Names
- Short Name
- SA + MRSA Islt/Spm
- Display Name
- Staphylococcus aureus and MRSA identified Molgen Nom (Islt/Spec)
- Consumer Name Alpha Get Info
- Staphylococcus aureus and MRSA test
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.70
- Change Reason
- Release 2.70: METHOD_TYP: Updated Method from "Probe.amp.tar" because other molecular methods can be used to report the same overall result.;
- Order vs. Observation
- Both
Example Answer List LL5519-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| MRSA positive, SA positive | LA30691-2 | ||
| MRSA negative, SA positive | LA30692-0 | ||
| MRSA negative, SA negative | LA30693-8 | ||
| Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) | LA15841-2 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 97326-3 | Staphylococcus aureus identification and resistance panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Staphylococo aureus y Staphylococo aureus resistente a meticilina identificados: |
| es-ES | Spanish (Spain) | Staphylococcus aureus y Staphylococcus aureus meticilín resistente identificado: |
| fr-FR | French (France) | Staphylococcus aureus et Staphylococcus aureus résistance identifiée à la méticilline: |
| it-IT | Italian (Italy) | Staphylococcus aureus & Staphylococcus aureus.meticillino resistente, identificato: Synonyms: Genetica molecolare Isolato o Campione Microbiologia Presenza o Identità Punto nel tempo (episodio) Staphylococcus aureus e Staphylococcus aureus, meticillino resistente Staphylococcus aureus resistente alla meticillina |
| nl-NL | Dutch (Netherlands) | Staphylococcus aureus & meticillineresistente Staphylococcus aureus (MRSA) geïdentificeerd: Synonyms: isolaat/specimen molgen MRSA |
| zh-CN | Chinese (China) | 金黄色葡萄球菌与金黄色葡萄球菌.甲氧西林耐药性 已鉴定的: Synonyms: 2,6-二甲氧基苯青霉素; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.