96309-0 Methicillin resistance mecA+mecC genes+SCCmec+OrfX junction [Presence] by Molecular method

Term Description

This assay detects the presence of nucleic acids within the mecA/mecC genes and SCCmec+OrfX junction (MREJ) found in methicillin-resistance bacteria. This assay detects but does not differentiate between mecA/C and MREJ.

Fully-Specified Name

Component

Bacterial methicillin resistance mecA+mecC genes+SCCmec+OrfX junction

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.69

Last Updated

Version 2.69 (ADD)

Order vs. Observation

Observation

Example Answer List LL744-4

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Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• Celbenin
• Dimethoxypenicillin
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• mecA+mecC+MREJ
• Metacillin
• Metin
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec
• Staficyn
• Staphicillin

85501-5 Carbapenem resistance blaVIM gene [Presence] by Molecular method

Term Description

This term is used to report the carbapenemase resistance bla(VIM) gene, detected in various specimens, including rectal swabs and isolates. It was created for, but is not limited in use to, the GeneXpert Carba-R test kit.

Part Descriptions

LP248277-8   Bacterial carbapenem resistance blaVIM gene
Verona integron-encoded metallo-β-lactamase (VIM) is part of a growing family of carbapenemases and includes at least 10 members. VIMs are one of the most common types of carbapenemases, with many variants in at least 23 species of Gram-negative bacilli from more than 40 regions of the world. PMID: 21449842 Studies have shown that a high percentage of patients with immunodeficiency and drug resistant nosocomial infections are infected with a VIM or IMP producing organism, particularly when the organism identified is Pseudomonas aeruginosa. PMID: 27563634 The two genes are often present together although they can also be present individually. Identifying the presence of these genes is important in monitoring drug resistance and determining the best antibiotic therapy methods. PMID: 28085553 Source: Regenstrief LOINC

Fully-Specified Name

Component

Bacterial carbapenem resistance blaVIM gene

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.61

Last Updated

Version 2.73 (MIN)

Change Reason

Updated System from "Anorectal/Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].

Order vs. Observation

Observation

Common Test Rank Get Info

4996

Example Answer List LL956-4

Member of these Panels

Language Variants Get Info

Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• CPR
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.

85827-4 Carbapenem resistance bla OXA-48-like gene [Presence] by Molecular method

Term Description

This test reports the presence of the OXA-48-like bacterial carbapenemase resistance type gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.

Part Descriptions

LP248274-5   Bacterial carbapenem resistance blaOXA-48-like gene
The existence of OXA-48 like class D beta-lactamases has been increasing in enterobacter species organisms. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. PMID: 24696435. The OXA-48 like class D beta-lactamase enzymes are highly resistant to penicillins and beta lactamase inhibitors and show a low resistance to carbapenems. These varied OXA-48-like beta-lactamases have been identified worldwide, including OXA-48-like producing Klebsiella pneumoniae with resistance to multiple drugs that emerged in Jordanian hospitals. Reports have shown that organisms producing OXA-48 like enzymes are either not resistant to broad-spectrum cephalosporins or show a decreased susceptibility to carbapenemase drugs. Identifying them can be a challenge. Screening and detection is required to prevent and control dissemination. PMID: 22499996 PMID: 26993738 Source: Regenstrief LOINC

Fully-Specified Name

Component

Bacterial carbapenem resistance blaOXA-48-like gene

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.61

Last Updated

Version 2.67 (MIN)

Change Reason

Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].

Order vs. Observation

Observation

Example Answer List LL360-9

Member of these Panels

Language Variants Get Info

Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• CPR
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.

73982-1 Carbapenem resistance blaNDM gene [Presence] by Molecular method

Term Description

Detection of bla(NDM) genotypes by molecular-based assays in isolates positive for gram-negative bacilli. Test is performed to determine resistance to carbapenems due to NDM (New Dehli metallo-β-lactamase) enzyme production.

Part Descriptions

LP173523-4   Bacterial carbapenem resistance blaNDM gene
New Delhi Metallo-beta-lactamase (NDM) is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics, including those in the carbapenem family. NDM-1 presents as the most dominant type. The NDM gene encodes beta-lactamase enzymes called carbapenemases. The most common bacteria that make the NDM enzyme are Gram-negative such as Escherichia coli and Klebsiella pneumoniae, but the gene for NDM can spread from one strain of bacteria to another by horizontal gene transfer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, NDM beta lactamases

Fully-Specified Name

Component

Bacterial carbapenem resistance blaNDM gene

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.46

Last Updated

Version 2.73 (MIN)

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].

Order vs. Observation

Both

Common Test Rank Get Info

4995

Example Answer List LL360-9

Member of these Panels

Language Variants Get Info

Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• CPR
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.

49617-4 Carbapenem resistance blaKPC gene [Presence] by Molecular method

Part Descriptions

LP64707-0   Bacterial carbapenem resistance blaKPC gene
Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance. Source: Regenstrief LOINC

Fully-Specified Name

Component

Bacterial carbapenem resistance blaKPC gene

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.22

Last Updated

Version 2.73 (MIN)

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].

Order vs. Observation

Both

Common Test Rank Get Info

1861

Example Answer List LL360-9

Member of these Panels

Language Variants Get Info

Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• Carbapenem resistance gene
• CPR
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.

85498-4 Carbapenem resistance blaIMP gene [Presence] by Molecular method

Term Description

This term is used to report the carbapenemase resistance bla(IMP) gene, detected in various specimens, including rectal swabs and isolates. It was created for, but is not limited in use to, the GeneXpert Carba-R test kit.

Part Descriptions

LP248294-3   Bacterial carbapenem resistance blaIMP gene
Plasmid-mediated IMP-type carbapenemases are currently known to have 17 varieties. Studies have revealed its establishment in Japan in the 1990s in enteric Gram-negative organisms, Pseudomonas species and Acinetobacter species. IMP genes usually co-exist with other resistance genes resulting in multi-drug resistance.
Studies have shown that a high percentage of patients with immunodeficiency and drug resistant nosocomial infections are infected with a VIM or IMP producing organism, particularly when the organism identified is pseudomonas aeruginosa. The two genes are often present together although they can also be present individually. Identifying the presence of these genes is important in monitoring drug resistance and determining the best antibiotic therapy methods.
PMID: 27563634 PMID: 28085553 Source: Regenstrief LOINC

Fully-Specified Name

Component

Bacterial carbapenem resistance blaIMP gene

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.61

Last Updated

Version 2.73 (MIN)

Change Reason

Updated System from "Anorectal/Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].

Order vs. Observation

Observation

Common Test Rank Get Info

4988

Example Answer List LL956-4

Member of these Panels

Language Variants Get Info

Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• CPR
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.

88250-6 Cephalosporin resistance blaCTX-M gene [Presence] by Molecular method

Part Descriptions

LP185698-0   Bacterial cephalosporin resistance blaCTX-M gene
The bacterial (CTX-M) gene is targeted to detect CTX-M type beta lactamases, a group of class A extended-spectrum beta-lactamases (ESBLs) that are a common cause of community-acquired infections. They exhibit powerful activity against cefotaxime and ceftriaxoane. CTX-M type ESBLs are rapidly spreading among Enterobacteriaceae worldwide and replacing TEM-type and SHV-type beta lactamases as the predominant ESBLs in many countries. They originate from Kluyvera species and can be separated into 5 different groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. CTX-M2, CTX-M3, and CTX-M14 are the most prevelant. More than 80 CTX-M allotypes are currently known (2014). Source: Regenstrief LOINC, PMID:18154526

Fully-Specified Name

Component

Bacterial cephalosporin resistance blaCTX-M gene

Property

PrThr

Time

Pt

System

Isolate/Specimen

Scale

Ord

Method

Molgen

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 2.63

Last Updated

Version 2.73 (MIN)

Change Reason

Removed parentheses from gene name, updated System from "Bld.pos growth" and Method from "Probe" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].

Order vs. Observation

Both

Common Test Rank Get Info

4969

Example Answer List LL744-4

Member of these Panels

Language Variants Get Info

Related Names

• ANTIBIOTIC SUSCEPTIBILITIES
• Bact
• c201
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Islt/Spm
• Isol
• Molecular genetics
• Ordinal
• PCR
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Resist
• Resistanc
• Resistant
• Resistent
• Screen
• Spec

92957-0 Respiratory syncytial virus RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP14244-5   Respiratory syncytial virus
Human respiratory syncytial virus (RSV), a negative-sense, single-stranded RNA virus of the family Paramyxoviridae, causes upper respiratory tract infections and bronchiolitis, an infection of the small airways that can cause wheezing and respiratory distress. Infants, especially those that were born prematurely, are particularly susceptible, and RSV bronchiolitis is a common cause of hospitalization for infants during the winter months. Certain groups of high-risk infants may be given palivizumab, a recombinant monoclonal antibody to RSV, as prophylaxis against RSV infection. Source: Regenstrief LOINC

LP39551-4   Respiratory syncytial virus RNA
The respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family and is an enveloped pleomorphic virus. RSV is spread through contact with respiratory droplets, contact with the patient and contact with contaminated surfaces. The rate of transmission is affected by outside temperature, humidity and precipitation. RSV infection spreads faster when the temperature is low and the humidity is high in temperate zones and when rainfall levels are high in tropical climates. RSV causes severe lower respiratory infections in infants and young children. Infants born prematurely are particularly susceptible. Symptoms of RSV infection include cough, low-grade fever and rhinorrhea. High risk adult populations including patients in residential facilities, those with heart and lung diseases and immunocompromised patients are susceptible to severe RSV infection and significant morbidity.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component

Respiratory syncytial virus RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

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Member of these Groups Get Info

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Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• DNA NUCLEIC ACID PROBE
• DNA probe
• HRSV
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• RSV
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92963-8 Parainfluenza virus RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP18337-3   Parainfluenza virus
Parainfluenza virus is from the family Paramyxoviridae and the genera Paramyxovirus which includes the parainfluenza viruses and the mumps virus. Paramyxoviruses are particles up to 300 nm in diameter. They are spiral, tube-like symmetrical nucleocapsids which contain a monopartite, single-stranded, negative-sense RNA genome and an RNA-directed RNA polymerase. There is a matrix protein at the base of a double-layered lipid envelope which contains spikes with two glycoproteins, a viral attachment protein and a fusion protein. The viral protein spikes in parainfluenza viruses have hemagglutinating and neuraminidase activities. As all paramyxoviruses are labile, they are quickly inactivated (e.g., by heat, detergents, ultraviolet light). Primary infections occur in young children and cause mild or severe upper and lower respiratory tract infections. Reinfection is common and results in milder manifestation. Transmission is by direct contact or by droplets. Parainfluenza virus diseases are usually endemic although they can be epidemic. [NCBI Books:NBK8461] Source: Regenstrief LOINC

Fully-Specified Name

Component

Parainfluenza virus RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• DNA NUCLEIC ACID PROBE
• DNA probe
• HPIV
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• Para
• Parainflu
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92967-9 Middle East respiratory syndrome coronavirus (MERS-CoV) RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP173753-7   Middle East respiratory syndrome coronavirus
Middle East Respiratory Syndrome (MERS) is an illness caused by the virus Middle East Respiratory Syndrome Coronovirus (MERS-CoV). The illness was first reported in Saudi Arabia in 2012, but was later found to have originated in Jordan in 2012. MERS has been found in camels leading to speculation that they may be the initial reservoir for the virus. The largest outbreak of MERS that has occurred outside of the Arabian Peninsula was in the Republic of Korea in 2015 and was linked to an individual who had been traveling in the Arabian Peninsula. The virus is probably spread through respiratory secretions from infected individuals though the exact mode of transmission is under investigation. Infection with MERS begins with an incubation period of 5-6 days followed by a severe acute illness that involves fever, shortness of breath and for patients with comorbidities or reduced immunity can lead to pneumonia and kidney failure. The mortality rate of MERS is 3-4 out of 10 people who are infected, though most of the people who die have underlying conditions. In addition, some people experience only cold-like symptoms and others have no symptoms at all. In the United States, most state laboratories are approved to test for MERS-CoV using the real-time reverse transcription-PCR assay developed by the CDC. The assay can be run on respiratory, serum and stool specimens.[CDC: coronavirus/mers] Source: Regenstrief LOINC

Fully-Specified Name

Component

Middle East respiratory syndrome coronavirus RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• Camel flu
• Corona virus
• DNA NUCLEIC ACID PROBE
• DNA probe
• HCoV-EMC/2012
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• MERS-CoV
• MERS-CoV RNA
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92976-0 Influenza virus B RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP14240-3   Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

Fully-Specified Name

Component

Influenza virus B RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• DNA NUCLEIC ACID PROBE
• DNA probe
• FLUB
• FLUBV
• FLUV
• Influ
• Influenza B
• Influenza B virus
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92977-8 Influenza virus A RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component

Influenza virus A RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Avian influenza
• Bird flu
• Breathing
• DNA NUCLEIC ACID PROBE
• DNA probe
• FLUA
• FLUAV
• FLUV
• Fowl plague
• Influ
• Influenza A
• Influenza A virus
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92956-2 Rhinovirus+Enterovirus RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP35705-0   Rhinovirus+Enterovirus
Human rhinoviruses (HRVs) can be categorized into three genetically distinct HRV groups, designated groups A, B, and C, within the genus Enterovirus and the family Picornaviridae. HRVs are positive-sense, single-stranded-RNA (ssRNA) viruses of approximately 7,200 bp. HRVs, which are the cause of more than one-half of cold like illnesses, are commonly associated with upper respiratory tract infection, otitis media, and sinusitis. PCR testing for respiratory virus detection has led to the recognition of HRV as a lower respiratory tract pathogen as well, especially in patients with asthma, infants, elderly patients, and immunocompromised individuals. At this time there are no approved antiviral therapies, and treatment is primarily supportive. Source: Regenstrief LOINC, PMCID: PMC3553670

LP35705-0   Rhinovirus+Enterovirus
Enteroviruses are small, non-enveloped, single stranded RNA viruses in the picornavirus family and include coxsackievirus, rhinovirus, echovirus, and poliovirus species. They are the most common viral pathogen worldwide, and clinical manifestations range from mild, cold-like symptoms to severe infections, including encephalitis, aseptic (viral) meningitis, and myocarditis. Enterovirus infection has also been associated with the onset of type I diabetes mellitus. PMID: 23764548 Source: Regenstrief LOINC, PMID: 23764548

Fully-Specified Name

Component

Rhinovirus+Enterovirus RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• DNA NUCLEIC ACID PROBE
• DNA probe
• Entero virus
• EV
• EV-PCR
• HRV
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Rhino virus
• RHV
• Ribonucleic acid
• RS
• RV+EV
• RV+EV RNA
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92978-6 Human metapneumovirus RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP34982-6   Human metapneumovirus
Human metapneumovirus (hMPV) is a Paramyxoviridae family virus that causes upper and lower respiratory tract infections in the very young, elderly and those with compromised immune systems. hMPV can vary in its size, shape and staining properties, and shares similar structure with avian pneumovirus (aMPV) and human respiratory syncytial virus (hRSV). Typically, molecular testing methods, like reverse transcriptase PCR (RT-PCR), are used to detect hMPV. hMPV is thought to be responsible for about 5% to 10% of pediatric hospitalizations of those suffering from acute respiratory tract infection. PMID: 24841931 Source: Regenstrief LOINC

Fully-Specified Name

Component

Human Metapneumovirus RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• DNA NUCLEIC ACID PROBE
• DNA probe
• hMPV
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92979-4 Human coronavirus RNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP35707-6   Human coronavirus
Coronaviruses (CoVs) are enveloped, non-segmented positive-sense RNA viruses that cause a range of respiratory infections in humans from mild respiratory symptoms to Severe Acute Respiratory Syndrome (SARS-CoV). Typically the virus is allowed to run its course and explicit identification of the virus is not needed. When identifying the virus is necessary for specific clinical cases or epidemiological studies, reverse transcription polymerase chain reaction (RT-PCR) is used, though serologic assays may be needed in cases where RNA is hard to isolate, no longer present, and for epidemiological studies. Treatment is primarily supportive. PMID: 25720466 Source: Regenstrief LOINC

Fully-Specified Name

Component

Human Coronavirus RNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• Corona virus
• DNA NUCLEIC ACID PROBE
• DNA probe
• HCoV
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92987-7 Adenovirus DNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP14061-3   Adenovirus
Adenoviruses, medium-sized (90-100 nm), non-enveloped icosohedral viruses with double-stranded DNA, have over 50 immunologically distinct types that cause infections in humans. Adenoviruses usually cause respiratory illness with symptoms ranging from the common cold to pneumonia, croup, and bronchitis. Adenoviruses can cause other illnesses such as gastroenteritis, conjunctivitis, cystitis, and less commonly, neurological disease. Infants and individuals with weakened immune systems are at high risk for severe complications of adenovirus infection and adenoviruses commonly cause acute respiratory illness in military recruits. Some asymptomatic people infected with adenoviruses have ongoing infections in their tonsils, adenoids, and intestines and can shed the virus for months or years. The virus can persist outside the body for long periods. Adenovirus infections can be detected using antigen detection, polymerase chain reaction assay, virus isolation, and serology. Typing is usually done by hemagglutination-inhibition and/or neutralization with type-specific antisera or by molecular methods. As of October 2014 there is no adenovirus vaccine for the general public, however an oral vaccine against types 4 and 7 was approved by the U.S. Food and Drug Administration in March 2011 for U.S. military personnel. The vaccine is recommended by the U.S. Department of Defense for military recruits entering basic training in order to prevent acute respiratory disease. Most adenovirus infections are mild and typically require only treatment of symptoms. Source: Centers for Disease Control and Prevention, CDC: Adenovirus

Fully-Specified Name

Component

Adenovirus DNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Adeno virus
• Amplif
• Amplification
• Amplified
• Breathing
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• HAdV
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92964-6 Mycoplasma pneumoniae DNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP14249-4   Mycoplasma pneumoniae
Mycoplasma pneumoniae is a filamentous cell without a cell well. It has an attachment organelle at its tip with protein adhesions which attach to sialoglycoproteins or sialoglycolipid receptors on the tracheal epithelium. Pneumonia is induced by local immunologic and phagocytic responses.
Mycoplasmas generally are the smallest self-replicating organisms possessing the smallest genomes (500 to 1000 genes). Mycoplasmas have several surface antigens; antibodies to these surface antigens inhibit their growth. While various serological tests have been developed and are useful in classification, the infections are persistent, frequently difficult to detect and difficult to cure. Mycoplasma pneumonaie infection affects the upper and lower respiratory tracts. Symptoms including cough, fever and headache may persist for several weeks. Infection occurs worldwide and affects mainly children five to nine years old. [NCBI Books:NBK7637] Source: Regenstrief LOINC

Fully-Specified Name

Component

Mycoplasma pneumoniae DNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• Enzootic pneumonia
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• M pneumo
• M pneumonia
• M pneumoniae
• Microbiology
• Myco
• Myco pneu
• Mycoplas
• Mycoplasm
• Mycoplasmoides pneumoniae
• Mycoplasmosis
• Mycoplsm
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Pneu
• pneum
• Pneumo
• Pneumon
• Pneumonia
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92969-5 Legionella pneumophila DNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP16720-2   Legionella pneumophila
Legionella pneumophila, a gram-negative bacillus, most commonly causes acute pneumonia (legionellosis). Transmission to humans is usually through aerosols of infected water sources such as fountains, misting systems, and drinking water. Severity of infections due to L. pneumophila range from mild (walking pneumonia) to fatal (multilobar pneumonia). Antimicrobial therapy usually includes erythromycin, with the addition of rifampin in severe cases. Initial response to therapy is usually rapid, but full recovery can take weeks to months. PMID: 21413250 Source: Regenstrief LOINC

Fully-Specified Name

Component

Legionella pneumophila DNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• L pneumo
• L pneumonphila
• LAT
• LCR
• Legion
• Legionela
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Pneu
• pneum
• Pneumophilia
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

92986-9 Chlamydophila pneumoniae DNA [Presence] in Lower respiratory specimen by NAA with non-probe detection

Part Descriptions

LP14396-3   Chlamydophila pneumoniae
Chlamydophila pneumoniae belongs to the Chlamydiaceae bacterial family. C pneumoniae is a frequent cause of acute respiratory infection, such as, pharyngitis, bronchitis, sinusitis, and community-acquired pneumonia (CAP). It is typically spread by coughing or sneezing, and initial infection usually occurs in school-age children. Most infections are self-limited, but outbreaks can occur in group settings such as schools and barracks. IgG antibodies to C. pneumonia can persist for years after infection. PMID: 22514397 Source: Regenstrief LOINC

Fully-Specified Name

Component

Chlamydophila pneumoniae DNA

Property

PrThr

Time

Pt

System

Respiratory system specimen.lower

Scale

Ord

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.82 (MIN)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• C pneum
• C pneumo
• C pneumoniae
• Chlamydia
• Chlamydia pneumoniae
• CPN
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Low
• Lower resp
• Lungs
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Pneu
• pneum
• Pneumo
• Pneumon
• Pneumonia
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification
• Twar agent

92947-1 Streptococcus pyogenes DNA [NCncRange] in Bronchoalveolar lavage by NAA with non-probe detection

Part Descriptions

LP15188-3   Streptococcus pyogenes
Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a species of gram-positive, coccoid, beta-hemolytic bacteria. It is responsible for a wide variety of both invasive and non-invasive diseases including scarlet fever, pharyngitis, impetigo, cellulitis, necrotizing fasciitis and toxic shock syndrome, as well as the sequelae of rheumatic fever and acute poststreptococcal glomerulonephritis. Invasive GAS infections can be associated with very high mortality rates. PMID: 26866208 Source: Regenstrief LOINC

Fully-Specified Name

Component

Streptococcus pyogenes DNA

Property

NCncRange

Time

Pt

System

BAL

Scale

SemiQn

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.75 (MAJ)

Order vs. Observation

Both

Example Answer List LL5239-0

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Bronchial alveolar lavage
• Bronchoalveolar lavage
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• GAS
• Group A Strep
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• NCncRng
• Nucleic acid sequence based analysis
• PCR
• Point in time
• Polymerase chain reaction
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• Random
• S pyogenes
• SDA
• SmQn
• Steptococcus Group A
• Strand Displacement Amplification
• Strep
• Strept
• Streptococci group A
• Streptococcus group A
• TMA
• Transcription mediated amplification

92946-3 Streptococcus pyogenes DNA [NCncRange] in Sputum by NAA with non-probe detection

Part Descriptions

LP15188-3   Streptococcus pyogenes
Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a species of gram-positive, coccoid, beta-hemolytic bacteria. It is responsible for a wide variety of both invasive and non-invasive diseases including scarlet fever, pharyngitis, impetigo, cellulitis, necrotizing fasciitis and toxic shock syndrome, as well as the sequelae of rheumatic fever and acute poststreptococcal glomerulonephritis. Invasive GAS infections can be associated with very high mortality rates. PMID: 26866208 Source: Regenstrief LOINC

Fully-Specified Name

Component

Streptococcus pyogenes DNA

Property

NCncRange

Time

Pt

System

Sputum

Scale

SemiQn

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.75 (MAJ)

Order vs. Observation

Both

Example Answer List LL5239-0

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• GAS
• Group A Strep
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Lower respiratory
• Microbiology
• NAA+n-prb
• NAA+probe
• NAAT
• NASBA
• NCncRng
• Nucleic acid sequence based analysis
• PCR
• Point in time
• Polymerase chain reaction
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• Random
• S pyogenes
• SDA
• SmQn
• Spt
• Sputum
• Steptococcus Group A
• Strand Displacement Amplification
• Strep
• Strept
• Streptococci group A
• Streptococcus group A
• TMA
• Transcription mediated amplification

92949-7 Streptococcus pneumoniae DNA [NCncRange] in Bronchoalveolar lavage by NAA with non-probe detection

Part Descriptions

LP14410-2   Streptococcus pneumoniae
Streptococcus pneumoniae are gram-positive cocci that are nonmotile and nonsporulating and usually require complex culture media. Older streptococcal cultures, beyond the most active growth period (the logarithmic phase), sometimes lose their gram-positive staining characteristics. S. pneumoniae are part of the normal respiratory tract flora. Disease usually results due to the acquisition of a new strain following a change in the normal flora, often due to a preceding virus. S. pneumonaie causes otitis media, sinusitis and pneumonia in the middle ear, sinuses or lungs, respectively. Meningitis can occur by bloodstream invasion from the lungs or by extension of otitis media or sinusitis to the meninges. Bacteremia can result in osteomyelitis (infection of bones) or arthritis (of joints). Most bacterial pneumonia occurring after the neonatal period is caused by S. pneumoniae. Pneumococcal pneumonia is seen most commonly in elderly or immunosuppressed individuals. In the United States, it is most prevalent in winter. Diagnosis is usually based on a sputum Gram stain and culture although blood or cerebrospinal fluid may be cultured. While penicillin has been the standard treatment, some strains have proven resistant to penicillin and multiple antibiotics. A vaccine exists. [NCBI Books:NBK7611] Source: Regenstrief LOINC

Fully-Specified Name

Component

Streptococcus pneumoniae DNA

Property

NCncRange

Time

Pt

System

BAL

Scale

SemiQn

Method

Non-probe.amp.tar

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.66

Last Updated

Version 2.75 (MAJ)

Order vs. Observation

Both

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